Patents by Inventor Mikael Trollsas

Mikael Trollsas has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COATINGS WITH TUNABLE MOLECULAR ARCHITECTURE FOR DRUG-COATED BALLOON
    Publication number: 20150196690
    Abstract: A drug delivery balloon is provided, the a balloon having an outer surface, and a tunable coating disposed on at least a length of the balloon surface. The tunable coating includes a first therapeutic agent and a first excipient, wherein the cytostatic therapeutic agent and the at least one excipient have a weight ratio of about 20:1 to about 1:20, and further wherein the coating provides increased efficiency of therapeutic transfer to a body lumen.
    Type: Application
    Filed: January 16, 2015
    Publication date: July 16, 2015
    Applicant: ABBOTT CARDIOVASCULAR SYSTEMS INC.
    Inventors: John Stankus, Mikael Trollsas, Syed Hossainy, Stephen Pacetti, Michael Ngo
  • METHOD OF TREATMENT WITH A BIOABSORBABLE STENT WITH TIME DEPENDENT STRUCTURE AND PROPERTIES AND REGIO-SELECTIVE DEGRADATION
    Publication number: 20150182360
    Abstract: A bioabsorbable polymeric stent with time dependent structure and properties and methods of treating a diseased blood vessel with the bioabsorable polymeric stent are disclosed. The structure and properties of the stent change with time and allow the vessel to be restored to a natural unstented state. The bioabsorbable stent loses mechanical integrity in a controlled manner due to modification of selected structural elements.
    Type: Application
    Filed: March 12, 2015
    Publication date: July 2, 2015
    Inventors: Mikael Trollsas, Dariush Davalian, Michael Huy Ngo, Hao-Ming Hsiao, Boris Anukhin, Syed Hossainy, David Gale
  • Tailored aliphatic polyesters for stent coatings
    Patent number: 9067002
    Abstract: An aliphatic polyester polymer for stent coating is described.
    Type: Grant
    Filed: February 20, 2014
    Date of Patent: June 30, 2015
    Assignee: Abbott Cardiovascular Systems Inc.
    Inventors: O. Mikael Trollsas, Lothar W. Kleiner, Syed F. A. Hossainy
  • Polymers for implantable devices exhibiting shape-memory effects
    Patent number: 9066992
    Abstract: The present invention is directed to polymeric compositions comprising a biodegradable copolymer that possesses shape-memory properties and implantable devices (e.g., drug-delivery stents) formed of materials (e.g., a coating) containing such compositions. The polymeric compositions can also contain at least one non-fouling moiety, at least additional biocompatible polymer, at least one biobeneficial material, at least one bioactive agent, or a combination thereof. The polymeric compositions are formulated to possess good mechanical, physical and biological properties. Moreover, implantable devices formed of materials comprising such compositions can be delivered to the treatment site in a conveniently compressed size and then can expand to dimensions appropriate for their medical functions.
    Type: Grant
    Filed: May 28, 2013
    Date of Patent: June 30, 2015
    Assignee: Abbott Cardiovascular Systems Inc.
    Inventors: John J. Stankus, O. Mikael Trollsas, Michael H. Ngo
  • Biodegradable Poly(Ester-Amide) And Poly(Amide) Coatings For Implantable Medical Devices With Enhanced Bioabsorption Times
    Publication number: 20150174299
    Abstract: This invention is generally related to coating layers for implantable medical devices, such as drug delivery vascular stents, and methods of fabricating coated implantable medical devices. Specifically various embodiments of the present invention include methods of fabricating and modulating of coating layers to enhance bioabsorption. The coating layers include poly(ester-amide) and/or poly(amide) polymers.
    Type: Application
    Filed: December 15, 2014
    Publication date: June 25, 2015
    Inventors: MICHAEL HUY NGO, Syed Faiyaz Ahmed Hossainy, Florencia Lim, O. Mikael Trollsas
  • Block Copolymer Comprising at least one Polyester Block and at least one Poly(ethylene glycol) Block
    Publication number: 20150174300
    Abstract: The present invention provides a block copolymer for a coating on an implantable device for controlling release of drug and methods of making and using the same.
    Type: Application
    Filed: December 22, 2014
    Publication date: June 25, 2015
    Inventors: O. Mikael Trollsas, Michael H. Ngo, Syed F. A. Hossainy, David J. Sherman
  • Soluble Coating Comprising Polyelectrolyte With Hydrophobic Counterions
    Publication number: 20150157771
    Abstract: The present invention provides an implantable device having a biosoluble coating comprising a polyelectrolyte and a counterion and the methods of making and using the same.
    Type: Application
    Filed: February 17, 2015
    Publication date: June 11, 2015
    Inventors: Syed F.A. Hossainy, O. Mikael Trollsas, Lothar W. Kleiner
  • BIOABSORBABLE COATING WITH TUNABLE HYDROPHOBICITY
    Publication number: 20150151030
    Abstract: The present invention relates to implantable medical devices coated with polymer having tunable hydrophobicity and their use in the treatment of vascular diseases.
    Type: Application
    Filed: January 26, 2015
    Publication date: June 4, 2015
    Inventors: Lothar W. Kleiner, John Stankus, Nam D. Pham, Michael H. Ngo, Bozena Zofia Maslanka, Syed Faiyaz Ahmed Hossainy, Mikael Trollsas, Yiwen Tang
  • IMPLANTABLE DEVICE HAVING A SLOW DISSOLVING POLYMER
    Publication number: 20150147402
    Abstract: The present invention provides an implantable device having a coating including a slow dissolving polymer or material and the methods of making and using the same.
    Type: Application
    Filed: November 17, 2014
    Publication date: May 28, 2015
    Inventors: O. Mikael Trollsas, Michael H. Ngo, David J. Sherman, Syed F.A. Hossainy
  • SHAPE MEMORY BIORESORBABLE POLYMER PERIPHERAL SCAFFOLDS
    Publication number: 20150142099
    Abstract: Bioabsorbable scaffolds having high crush recoverability, high fracture resistance, and reduced or no recoil due to self expanding properties at physiological conditions are disclosed. The scaffolds are made from a random copolymer of PLLA and a rubbery polymer such as polycaprolactone.
    Type: Application
    Filed: January 22, 2015
    Publication date: May 21, 2015
    Inventors: John S. Stankus, Hugh Zhao, Mikael Trollsas, Syed Faiyaz Ahmed Hossainy, Michael H. Ngo, Yunbing Wang, Benny Serna
  • Shape memory bioresorbable polymer peripheral scaffolds
    Patent number: 8968387
    Abstract: Bioabsorbable scaffolds having high crush recoverability, high fracture resistance, and reduced or no recoil due to self expanding properties at physiological conditions are disclosed. The scaffolds are made from a random copolymer of PLLA and a rubbery polymer such as polycaprolactone.
    Type: Grant
    Filed: July 23, 2012
    Date of Patent: March 3, 2015
    Assignee: Abbott Cardiovascular Systems Inc.
    Inventors: John S. Stankus, Hugh Zhao, Mikael Trollsas, Syed Faiyaz Ahmed Hossainy, Michael H. Ngo, Yunbing Wang, Benny Serna
  • Bioabsorbable coating with tunable hydrophobicity
    Patent number: 8961589
    Abstract: The present invention relates to implantable medical devices coated with polymer having tunable hydrophobicity and their use in the treatment of vascular diseases.
    Type: Grant
    Filed: August 1, 2007
    Date of Patent: February 24, 2015
    Assignee: Abbott Cardiovascular Systems Inc.
    Inventors: Lothar W. Kleiner, John Stankus, Nam D. Pham, Michael H. Ngo, Bozena Zofia Maslanka, Syed Faiyaz Ahmed Hossainy, Mikael Trollsas, Yiwen Tang
  • Coatings with tunable molecular architecture for drug-coated balloon
    Patent number: 8951595
    Abstract: A drug delivery balloon is provided, the a balloon having an outer surface, and a tunable coating disposed on at least a length of the balloon surface. The tunable coating includes a first therapeutic agent and a first excipient, and can include a second therapeutic agent and a second excipient. The first and second therapeutic agents have different dissolution rates during balloon inflation and therefore provide a coating that is tunable.
    Type: Grant
    Filed: December 11, 2009
    Date of Patent: February 10, 2015
    Assignee: Abbott Cardiovascular Systems Inc.
    Inventors: John Stankus, Mikael Trollsas, Syed Hossainy, Stephen Pacetti, Michael Ngo
  • PROHEALING PIEZOELECTRIC COATINGS
    Publication number: 20140370072
    Abstract: Provided herein is a prohealing piezoelectric coating and the method of making and using the same.
    Type: Application
    Filed: September 3, 2014
    Publication date: December 18, 2014
    Inventors: Syed Faiyaz Ahmed Hossainy, Mikael Trollsas, Lothar Walter Kleiner
  • ELASTIN-BASED COPOLYMERS
    Publication number: 20140363563
    Abstract: A copolymer comprising a block of an elastin pentapeptide and method of making and using the copolymer are provided.
    Type: Application
    Filed: June 18, 2014
    Publication date: December 11, 2014
    Inventors: Syed F.A. Hossainy, Mikael Trollsas, Thierry Glauser, Yiwen Tang
  • COUPLED SCAFFOLD SEGMENTS
    Publication number: 20140364935
    Abstract: A scaffold is formed by several segments joined or connected to each other by only at least one coupling. The coupling decouples the segments in the axial direction over a finite distance of axial displacement. The scaffold when implanted in a peripheral vessel reduces loading on rings of a segment due to the decoupling of the segments in the axial direction over the finite distance.
    Type: Application
    Filed: June 5, 2013
    Publication date: December 11, 2014
    Inventors: Erik David Eli, Syed Hossainy, Mikael Trollsas, Michael H. Ngo, Stephen Pacetti, Michael Green, John Papp
  • ELASTIN-BASED COPOLYMERS AND METHOD OF USING
    Publication number: 20140356519
    Abstract: A copolymer comprising a block of an elastin pentapeptide and method of making and using the copolymer are provided.
    Type: Application
    Filed: June 18, 2014
    Publication date: December 4, 2014
    Inventors: Syed F.A. Hossainy, Mikael Trollsas, Thierry Glauser, Yiwen Tang
  • Amorphous or semi-crystalline poly(ester amide) polymer with a high glass transition temperature
    Patent number: 8889172
    Abstract: The present invention provides an implantable device formed from an amorphous or semi-crystalline PEA polymer with a high Tg and methods of making and using the same.
    Type: Grant
    Filed: April 30, 2008
    Date of Patent: November 18, 2014
    Assignee: Abbott Cardiovascular Systems Inc.
    Inventors: Mikael Trollsas, Florencia Lim, Thierry Glauser, Chris Feezor
  • Implantable device having a coating with a triblock copolymer
    Patent number: 8889170
    Abstract: The present invention provides an implantable device having a coating including a slow dissolving polymer or material and the methods of making and using the same.
    Type: Grant
    Filed: January 10, 2014
    Date of Patent: November 18, 2014
    Assignee: Abbott Cardiovascular Systems Inc.
    Inventors: O. Mikael Trollsas, Michael Huy Ngo, David J. Sherman, Syed Faiyaz Ahmed Hossainy
  • Polymer Blends For Drug Delivery Stent Matrix With Improved Thermal Stability
    Publication number: 20140335143
    Abstract: Various embodiments of the present invention generally relate to a polymer blend composition used for coating a medical device that exhibits improved thermal stability. The invention also encompasses implantable medical devices coated the aforementioned coating.
    Type: Application
    Filed: May 15, 2014
    Publication date: November 13, 2014
    Applicant: Abbott Cardiovascular Systems Inc.
    Inventors: Florencia Lim, Bozena Z. Maslanka, Yiwen Tang, O. Mikael Trollsas