Patents by Inventor Mikael Ulf Johan Dahlstrom

Mikael Ulf Johan Dahlstrom has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Benzothiazepine derivatives
    Patent number: 8067584
    Abstract: Compounds of formula: (1) pharmaceutically acceptable salts, solvates, solvates of such salts and prodrugs thereof and their use as ileal bile acid transport (IBAT) inhibitors for the treatment of hyperlipidaemia are described. Processes for their manufacture and pharmaceutical compositions containing them are also described.
    Type: Grant
    Filed: February 23, 2004
    Date of Patent: November 29, 2011
    Assignee: Albireo AB
    Inventors: Ingemar Starke, Suzanne Alenfalk, Mats Peter Nordberg, Mikael Ulf Johan Dahlstrom, Stig Jonas Bostrom, Malin Anita Lemurell, Andreas Christer Wallberg
  • Diphenylazetidinone derivatives for treating disorders of the lipid metabolism
    Patent number: 7470678
    Abstract: Compounds of formula (I): (wherein variable groups are as defined within) pharmaceutically acceptable salts, solvates, solvates of such salts and prodrugs thereof and their use as cholesterol absorption inhibitors for the treatment of hyperlipidaemia are described.
    Type: Grant
    Filed: July 1, 2003
    Date of Patent: December 30, 2008
    Assignee: AstraZeneca AB
    Inventors: Ingemar Starke, Mikael Ulf Johan Dahlstrom, Ann-Margret Lindqvist, Mats Peter Nordberg, Tore Skjaret, Malin Anita Lemurell
  • Therapeutic agents
    Patent number: 7462644
    Abstract: The present invention provides the S enantiomer of a compound of formula I wherein R1 represents chloro, trifluoromethyl or trifluoromethoxy, R2 represents H or fluoro and R3 represents a C2-4alkyl group as well as pharmaceutically acceptable salts, solvates and prodrugs thereof, to processes for preparing such compounds, to their the utility in treating clinical conditions including lipid disorders (dyslipidemias) whether or not associated with insulin resistance, to methods for their therapeutic use and to pharmaceutical compositions containing them.
    Type: Grant
    Filed: December 19, 2003
    Date of Patent: December 9, 2008
    Assignee: AstraZeneca AB
    Inventors: Eva-Lotte Lindstedt Alstermark, Anna Christina Olsson, Lanna Li, Carl-Johan Aurell, Anna Minidis, Esmail Yousefi-Salakdeh, Mikael Ulf Johan Dahlström
  • Benzothiadiazepine derivatives, processes for their preparation and pharmaceutical compositions containing them
    Patent number: 7238684
    Abstract: The present invention relates to compounds of formula (I): wherein Rv, R1, R2, Rx, Ry, R3, R4, R5, R6, Rz and v are as defined within; pharmaceutically acceptable salts, solvates, solvates or such salts and prodrugs thereof and their use as ileal bile acid transport (IBAT) inhibitors for the treatment of hyperlipidaemia. Processes for their manufacture and pharmaceutical compositions containing them are also described.
    Type: Grant
    Filed: April 23, 2003
    Date of Patent: July 3, 2007
    Assignee: AstraZeneca AB
    Inventors: Ingemar Starke, Mikael Ulf Johan Dahlstrom, Mats Peter Nordberg, Suzanne Alenfalk, Andreas Christer Wallberg, Stig Jonas Bostrom
  • Benzothiepine ileal bile acid transport inhibitors
    Patent number: 7226943
    Abstract: The present invention relates to compounds of formula (I) wherein variable groups are as defined within; pharmaceutically acceptable salts, solvates, solvates of such salts and prodrugs thereof and their use as ileal bile acid transport (IBAT) inhibitors for the treatment of hyperlipidaemia.
    Type: Grant
    Filed: September 5, 2002
    Date of Patent: June 5, 2007
    Assignee: AstraZeneca AB
    Inventors: Ingemar Starke, Mikael Ulf Johan Dahlstrom, David Blomberg
  • Benzothiazepine derivatives
    Patent number: 7192946
    Abstract: The present invention relates to compounds of formula (I), wherein variable groups are as defined within; pharmaceutically acceptable salts, solvates, solvates of such salts and prodrugs thereof and their use as ileal bile acid transport (IBAT) inhibitors for the treatment of hyperlipidaemia.
    Type: Grant
    Filed: August 30, 2002
    Date of Patent: March 20, 2007
    Assignee: AstraZeneca AB
    Inventors: Ingemar Starke, Mikael Ulf Johan Dahlstrom, David Blomberg, Suzanne Alenfalk, Peter Nordberg, Andreas Christer Wallberg, Stig Jonas Bostrom
  • Peptides derivatives comprising thiazepine group for the treatment of hyperlipidemic conditions
    Patent number: 7192947
    Abstract: The present invention relates to compounds of formula (I): (wherein variable groups are as defined within) pharmaceutically acceptable salts, solvates, solvates of such salts and prodrugs thereof and their use as ileal bile acid transport (IBAT) inhibitors for the treatment of hyperlipidaemia.
    Type: Grant
    Filed: June 10, 2003
    Date of Patent: March 20, 2007
    Assignee: AstraZeneca AB
    Inventors: Ingemar Starke, Mikael Ulf Johan Dahlstrom, Suzanne Alenfalk, Tore Skjaret, Malin Lemurell
  • Benzothiazepine and benzothiazepine derivatives with ileal bile acid transport (IBAT) inhibotory activity for the treatment hyperlipidaemia
    Patent number: 7132416
    Abstract: The present invention relates to compounds of formula (I) wherein Rv, R1, R2, Rx, Ry, M, Rz, v, R3, R4, R5 and R6 are as defined within; pharmaceutically acceptable salts, solvates, solvates of such salts and prodrugs thereof and their use as ileal bile acid transport (IBAT) inhibitors for the treatment of hyperlipidaemia. Processes for their manufacture and pharmaceutical compositions containing them are also described.
    Type: Grant
    Filed: September 5, 2002
    Date of Patent: November 7, 2006
    Assignee: AstraZeneca AB
    Inventors: Ingemar Starke, Mikael Ulf Johan Dahlstrom, David Blomberg, Suzanne Alenfalk, Tore Skjaret, Malin Lemurell
  • Benzothiazepine derivatives for the treatment of hyperlipidemia
    Patent number: 7125864
    Abstract: The present invention relates to compounds of formula (I): wherein variable groups are as defined within; pharmaceutically acceptable salts, solvates, solvates of such salts and prodrugs thereof and their use as ileal bile acid transport (IBAT) inhibitors for the treatment of hyperlipidemia.
    Type: Grant
    Filed: September 5, 2002
    Date of Patent: October 24, 2006
    Assignee: AstraZeneca AB
    Inventors: Ingemar Starke, Mikael Ulf Johan Dahlstrom, David Blomberg
  • Chemical compounds
    Publication number: 20050143368
    Abstract: The present invention relates to compounds of formula (1): wherein Rv, R1, R2, Rx, Ry, R3, R4, R5, R6, Rz and v are as defined within; pharmaceutically acceptable salts, solvates, solvates or such salts and prodrugs thereof and their use as ileal bile acid transport (IBAT) inhibitors for the treatment of hyperlipidaemia. Processes for their manufacture and pharmaceutical compositions containing them are also described.
    Type: Application
    Filed: April 23, 2003
    Publication date: June 30, 2005
    Inventors: Ingemar Starke, Mikael, Ulf, Johan Dahlstrom, Mats, Peter Nordberg, Suzanne Alenfalk, Andreas, Christer Wallberg, Stig, Jonas Bostrom
  • Therapeutic agents
    Publication number: 20050131068
    Abstract: The present invention provides the S enantiomer of a compound of formula I wherein R1 represents chloro, trifluoromethyl or trifluoromethoxy, R2 represents H or fluoro and R3 represents a C2-4alkyl group as well as pharmaceutically acceptable salts, solvates and prodrugs thereof, to processes for preparing such compounds, to their the utility in treating clinical conditions including lipid disorders (dyslipidemias) whether or not associated with insulin resistance, to methods for their therapeutic use and to pharmaceutical compositions containing them.
    Type: Application
    Filed: December 19, 2003
    Publication date: June 16, 2005
    Inventors: Eva-Lotte Alstermark, Anna, Cristina Olsson, Lanna Li, Carl-Johan Aurell, Anna Minidis, Esmail Yousefi-Salakdeh, Mikael, Ulf, Johan Dahlstrom
  • Benzothiazepine derivatives
    Publication number: 20040254160
    Abstract: The present invention relates to compounds of formula (I), wherein variable groups are as defined within; pharmaceutically acceptable salts, solvates, solvates of such salts and prodrugs thereof and their use as ileal bile acid transport (IBAT) inhibitors for the treatment of hyperlipidaemia. Processes for their manufacture and pharmaceutical compositions containing them are also described.
    Type: Application
    Filed: July 23, 2004
    Publication date: December 16, 2004
    Inventors: Ingemar Starke, Mikael ulf Johan Dahlstrom, David Blomberg, Suzanne Alenfalk, Peter Nordberg, Andreas Christer Wallberg, Stig Jonas Bostrom