Patents by Inventor Mikari Watanabe

Mikari Watanabe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 1-(2-deoxy-2-fluoro-4-thio-beta-D-arabinofuranosyl)cytosine
    Patent number: 6147058
    Abstract: The present invention relates to 1-(2-deoxy-2-fluoro-4-thio-beta-D-arabinofuranosyl)cytosines having excellent antitumor activity, represented by formula [I]: ##STR1## wherein R represents a hydrogen atom or a phosphoric acid residue, and to a process for the production and use thereof.
    Type: Grant
    Filed: June 29, 1998
    Date of Patent: November 14, 2000
    Assignee: Yamasa Corporation
    Inventors: Yuichi Yoshimura, Kenji Kitano, Shinji Miura, Haruhiko Machida, Mikari Watanabe
  • 9-(2-deoxy-2-fluoro-4-thio-beta-D-arabinofuranosyl)purine derivatives
    Patent number: 6103707
    Abstract: The present invention relates to 9-(2-deoxy-2-fluoro-4-thio-beta-D-arabinofuranosyl)purine derivatives having antiviral activity, represented by formula [I]: ##STR1## wherein B represents a base selected from the group consisting of purine, azapurine and deazapurine, which may be substituted with halogen, alkyl, haloalkyl, alkenyl, haloalkenyl, alkynyl, amino, alkylamino, hydroxyl, hydroxyamino, aminoxy, alkoxy, mercapto, alkylmercapto, aryl, aryloxy or cyano; and R represents a hydrogen atom or a phosphoric acid residue, and to a process for the production and use thereof.
    Type: Grant
    Filed: June 29, 1998
    Date of Patent: August 15, 2000
    Assignee: Yamasa Corporation
    Inventors: Kohei Yamada, Yuichi Yoshimura, Haruhiko Machida, Mikari Watanabe
  • Purine 4'-thioarabinonucleosides
    Patent number: 5817639
    Abstract: The present invention provides a novel purine 4'-thioarabinonucleoside represented by the following formula ?1!: ##STR1## wherein B represents a purine base other than adenine. Also disclosed are a method for preparing the purine 4'-thioarabinonucleoside and pharmaceutical compositions containing the purine 4'-thioarabinonucleoside.
    Type: Grant
    Filed: July 12, 1996
    Date of Patent: October 6, 1998
    Assignee: Yamasa Corporation
    Inventors: Mikari Watanabe, Yuichi Yoshimura, Shinji Sakata, Noriyuki Ashida, Haruhiko Machida