Patents by Inventor Mike Cable

Mike Cable has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method and apparatus for selective removal of cells from a cell suspension by mechanical lysis
    Patent number: 12072333
    Abstract: In some embodiments, the present disclosure provides an apparatus and methods for selectively lysing cells from a cell suspension including disassociating a population of cells from a tissue sample, the population of cells including a population of one or more viable cells and a population of one or more dead and dying cells, exposing the population of cells to at least one pulse of fluid shear stress having a force along a conduit wall of from about 500 dyn/cm2 to about 2500 dyn/cm2 to substantially lyse the population of one or more dead or dying cells, leaving the population of one or more viable cells substantially intact, and collecting the population of one or more viable cells.
    Type: Grant
    Filed: November 2, 2017
    Date of Patent: August 27, 2024
    Assignees: University of Iowa Research Foundation, SynderBio, Inc.
    Inventors: Michael D. Henry, Benjamin Krog, Sarah Vigmostad, Mike Cable
  • METHOD AND APPARATUS FOR SELECTIVE REMOVAL OF CELLS FROM A CELL SUSPENSION BY MECHANICAL LYSIS
    Publication number: 20190265239
    Abstract: In some embodiments, the present disclosure provides an apparatus and methods for selectively lysing cells from a cell suspension including disassociating a population of cells from a tissue sample, the population of cells including a population of one or more viable cells and a population of one or more dead and dying cells, exposing the population of cells to at least one pulse of fluid shear stress having a force along a conduit wall of from about 500 dyn/cm2 to about 2500 dyn/cm2 to substantially lyse the population of one or more dead or dying cells, leaving the population of one or more viable cells substantially intact, and collecting the population of one or more viable cells.
    Type: Application
    Filed: November 2, 2017
    Publication date: August 29, 2019
    Applicants: UNIVERSITY OF IOWA RESEARCH FOUNDATION, SYNDERBIO, INC.
    Inventors: Michael D. Henry, Benjamin Krog, Sarah Vigmostad, Mike Cable