Patents by Inventor Mike Gravett

Mike Gravett has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Diagnosis of intra-uterine infection by proteomic analysis of cervical-vaginal fluids
    Patent number: 8068990
    Abstract: The invention concerns the identification of proteomes of biological fluids and their use in determining the state of maternal/fetal conditions, including maternal conditions of fetal origin, chromosomal aneuploidies, and fetal diseases associated with fetal growth and maturation. In particular, the invention concerns a comprehensive proteomic analysis of human amniotic fluid (AF) and cervical vaginal fluid (CVF), and the correlation of characteristic changes in the normal proteome with various pathologic maternal/fetal conditions, such as intra-amniotic infection, pre-term labor, and/or chromosomal defects. The invention further concerns the identification of biomarkers and groups of biomarkers that can be used for non-invasive diagnosis of various pregnancy-related disorders, and diagnostic assays using such biomarkers.
    Type: Grant
    Filed: November 9, 2006
    Date of Patent: November 29, 2011
    Assignee: Hologic, Inc.
    Inventors: Ron Rosenfeld, Srinivasa Nagalla, Mike Gravett
  • Proteomic analysis of biological fluids
    Publication number: 20090055099
    Abstract: The invention concerns the identification of proteomes of biological fluids and their use in determining the state of maternal/fetal conditions, including maternal conditions of fetal origin, chromosomal aneuploidies, and fetal diseases associated with fetal growth and maturation. In particular, the invention concerns the identification of the proteome of amniotic fluid (multiple proteins representing the composition of amniotic fluid) and the correlation of characteristic changes in the normal proteome with various pathologic maternal/fetal conditions, such as intra-amniotic infection, or chromosomal defects.
    Type: Application
    Filed: June 22, 2006
    Publication date: February 26, 2009
    Inventors: Ron Rosenfeld, Sri Nagalla, Mike Gravett
  • Proteomic analysis of biological fluids
    Publication number: 20080299594
    Abstract: The invention concerns the identification of proteomes of biological fluids and their use in determining the state of maternal/fetal conditions, including maternal conditions of fetal origin, chromosomal aneuploidies, and fetal diseases associated with fetal growth and maturation. In particular, the invention concerns the identification of the proteome of amniotic fluid (multiple proteins representing the composition of amniotic fluid) and the correlation of characteristic changes in the normal proteome with various pathologic maternal/fetal conditions, such as intra-amniotic infection, or chromosomal defects.
    Type: Application
    Filed: July 8, 2008
    Publication date: December 4, 2008
    Inventors: Ron Rosenfeld, Sri Nagalla, Mike Gravett
  • Proteomic analysis of biological fluids
    Publication number: 20070161125
    Abstract: The invention concerns the identification of proteomes of biological fluids and their use in determining the state of maternal/fetal conditions, including maternal conditions of fetal origin, chromosomal aneuploidies, and fetal diseases associated with fetal growth and maturation. In particular, the invention concerns a comprehensive proteomic analysis of human amniotic fluid (AF) and cervical vaginal fluid (CVF), and the correlation of characteristic changes in the normal proteome with various pathologic maternal/fetal conditions, such as intra-amniotic infection, pre-term labor, and/or chromosomal defects. The invention further concerns the identification of biomarkers and groups of biomarkers that can be used for non-invasive diagnosis of various pregnancy-related disorders, and diagnostic assays using such biomarkers.
    Type: Application
    Filed: November 9, 2006
    Publication date: July 12, 2007
    Inventors: Ron Rosenfeld, Srinivasa Nagalla, Mike Gravett
  • Proteomic analysis of biological fluids
    Patent number: 7191068
    Abstract: The invention concerns the identification of proteomes of biological fluids and their use in determining the state of maternal/fetal conditions, including maternal conditions of fetal origin, chromosomal aneuploidies, and fetal diseases associated with fetal growth and maturation. In particular, the invention concerns the identification of the proteome of amniotic fluid (multiple proteins representing the composition of amniotic fluid) and the correlation of characteristic changes in the normal proteome with various pathologic maternal/fetal conditions, such as intra-amniotic infection, or chromosomal defects.
    Type: Grant
    Filed: March 25, 2003
    Date of Patent: March 13, 2007
    Assignee: Proteogenix, Inc.
    Inventors: Ron Rosenfeld, Sri Nagalla, Mike Gravett
  • Proteomic analysis of biological fluids
    Publication number: 20040197930
    Abstract: The invention concerns the identification of proteomes of biological fluids and their use in determining the state of maternal/fetal conditions, including maternal conditions of fetal origin, chromosomal aneuploidies, and fetal diseases associated with fetal growth and maturation. In particular, the invention concerns the identification of the proteome of amniotic fluid (multiple proteins representing the composition of amniotic fluid) and the correlation of characteristic changes in the normal proteome with various pathologic maternal/fetal conditions, such as intra-amniotic infection, or chromosomal defects.
    Type: Application
    Filed: March 25, 2003
    Publication date: October 7, 2004
    Inventors: Ron Rosenfeld, Sri Nagalla, Mike Gravett