Patents by Inventor Mike Rigby

Mike Rigby has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Bicyclic peptide ligands specific for TREM2
    Patent number: 11904020
    Abstract: The present invention relates to polypeptides which are covalently bound to molecular scaffolds such that two or more peptide loops are subtended between attachment points to the scaffold. In particular, the invention describes peptides which bind to TREM2. The invention also relates to multimeric binding complexes which comprise at least two of said bicyclic peptide ligands. The invention also includes pharmaceutical compositions comprising said peptide ligands and multimeric binding complexes and the use of said peptide ligands, multimeric binding complexes and pharmaceutical compositions in preventing, suppressing or treating a disease or disorder mediated by TREM2.
    Type: Grant
    Filed: March 18, 2022
    Date of Patent: February 20, 2024
    Assignee: BicycleTx Limited
    Inventors: Paul Brennan, Amy Brown, Liuhong Chen, John Davis, Yuliya Demydchuk, Donatella Di Rienzo, Ellen Gowans, Rama McCrory, Emma Mead, Emma Murphy, Mike Rigby, Michael Skynner, Tom Smith, Steven Stanway
  • MONEY ITEM HANDLING SYSTEM AND METHOD
    Publication number: 20220398889
    Abstract: A money item handling system, comprising a mixed denomination money item storage region comprising at least one money item outlet routing; at least one money item collection zone arranged to receive mixed denomination money items outlet through the at least one money item outlet routing; at least one money item conveyor arranged to collect money items from the at least one money item collection zone and to convey money items collected from the at least one money item collection zone around a path of the at least one money item conveyor; at least one money item flow control apparatus; and at least one actuator configured to controllably actuate the at least one money item flow control apparatus to selectively control movement of money items from the mixed denomination money item storage region to the at least one money item collection zone.
    Type: Application
    Filed: October 26, 2020
    Publication date: December 15, 2022
    Inventors: Mike RIGBY, Kevin MULVEY, Ian PEERS
  • BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR TREM2
    Publication number: 20220296726
    Abstract: The present invention relates to polypeptides which are covalently bound to molecular scaffolds such that two or more peptide loops are subtended between attachment points to the scaffold. In particular, the invention describes peptides which bind to TREM2. The invention also relates to multimeric binding complexes which comprise at least two of said bicyclic peptide ligands. The invention also includes pharmaceutical compositions comprising said peptide ligands and multimeric binding complexes and the use of said peptide ligands, multimeric binding complexes and pharmaceutical compositions in preventing, suppressing or treating a disease or disorder mediated by TREM2.
    Type: Application
    Filed: March 18, 2022
    Publication date: September 22, 2022
    Applicant: BicycleTx Limited
    Inventors: Paul Brennan, Amy Brown, Liuhong Chen, John Davis, Yuliya Demydchuk, Donatella Di Rienzo, Ellen Gowans, Rama McCrory, Emma Mead, Emma Murphy, Mike Rigby, Michael Skynner, Tom Smith, Steven Stanway