Patents by Inventor Mike Tu

Mike Tu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted imidazoles useful for treating type II diabetes
    Patent number: 8329920
    Abstract: The present invention provides Formula (1A) compounds that act as glucokinase activators; pharmaceutical compositions thereof; and methods of treating diseases, disorders, or conditions mediated by glucokinase. X, Y, Z, R1, R2, R3, and R4 are as described herein.
    Type: Grant
    Filed: May 26, 2011
    Date of Patent: December 11, 2012
    Assignee: Pfizer Inc.
    Inventors: John William Benbow, Jihong Lou, Jeffrey Allen Pfefferkorn, Meihua Mike Tu
  • Substituted Heteroaryls
    Publication number: 20120225910
    Abstract: The present invention provides Formula (1A) compounds that act as glucokinase activators; pharmaceutical compositions thereof; and methods of treating diseases, disorders, or conditions mediated by glucokinase. X, Y, Z, R1, R2, R3, and R4 areas described herein.
    Type: Application
    Filed: April 23, 2012
    Publication date: September 6, 2012
    Applicant: PFIZER INC.
    Inventors: Jeffrey Allen Pfefferkorn, Meihua Mike Tu
  • GLUCAGON RECEPTOR MODULATORS
    Publication number: 20120202834
    Abstract: The present invention provides a compound of Formula (I) or a pharmaceutically acceptable salt thereof wherein R1, R2, R3, A1, A2, A3, A4, L, B1, B2, B3 and B4 are as defined herein. The compounds of Formula I have been found to act as glucagon antagonists or inverse agonists. Consequently, the compounds of Formula I and the pharmaceutical compositions thereof are useful for the treatment of diseases, disorders, or conditions mediated by glucagon.
    Type: Application
    Filed: February 7, 2012
    Publication date: August 9, 2012
    Applicant: PFIZER INC.
    Inventors: Gary Erik Aspnes, Mary Theresa Didiuk, Kevin James Filipski, Angel Guzman-Perez, Esther Cheng Yin Lee, Jeffrey Allen Pfefferkorn, Benjamin Dawson Stevens, Meihua Mike Tu
  • Glucagon Receptor Modulators
    Publication number: 20120165343
    Abstract: The present invention provides a compound of Formula (I) or a pharmaceutically acceptable salt thereof wherein R1, R2, R3, A1, A2, A3, A4, L, B1, B2, B3 and B4 are as defined herein. The compounds of Formula I have been found to act as glucagon antagonists or inverse agonists. Consequently, the compounds of Formula I and the pharmaceutical compositions thereof are useful for the treatment of diseases, disorders, or conditions mediated by glucagon.
    Type: Application
    Filed: December 22, 2011
    Publication date: June 28, 2012
    Applicant: Pfizer Inc.
    Inventors: Gary Erik Aspnes, Mary Theresa Didiuk, Kevin James Filipski, Angel Guzman-Perez, Jeffrey Allen Pfefferkorn, Benjamin Dawson Stevens, Meihua Mike Tu
  • Substituted Heteroaryls
    Publication number: 20110230445
    Abstract: The present invention provides Formula (1A) compounds that act as glucokinase activators; pharmaceutical compositions thereof; and methods of treating diseases, disorders, or conditions mediated by glucokinase. X, Y, Z, R1, R2, R3, and R4 are as described herein.
    Type: Application
    Filed: May 26, 2011
    Publication date: September 22, 2011
    Inventors: John William Benbow, Jihong Lou, Jeffrey Allen Pfefferkorn, Meihua Mike Tu
  • Substituted imidazole propanamide glucokinase activators
    Patent number: 7977367
    Abstract: The present invention provides Formula (1A) compounds that act as glucokinase activators; pharmaceutical compositions thereof; and methods of treating diseases, disorders, or conditions mediated by glucokinase. X, Y, Z, R1, R2, R3, and R4 are as described herein.
    Type: Grant
    Filed: September 9, 2009
    Date of Patent: July 12, 2011
    Assignee: Pfizer Inc
    Inventors: John William Benbow, Jihong Lou, Jeffrey Allen Pfefferkorn, Meihua Mike Tu
  • Systems and methods for resolving signal-to-noise ratio margin difference in dual latency discrete multi-tone-based xDSL systems under colored noise conditions
    Patent number: 7907658
    Abstract: Systems and methods for resolving signal-to-noise ratio margin difference n dual latency discrete multi-tone (DMT)-based xDSL systems under colored noise conditions. Rather than assuming a constant power spectral density (PSD) for noise over fast and interleaved data paths of a dual latency system, band edges vulnerable to colored noise are determined and data on the fast data path is allocated away from these band edges. Also, receive windowing may be used to further enhance performance.
    Type: Grant
    Filed: August 31, 2006
    Date of Patent: March 15, 2011
    Assignee: Ikanos Communications, Inc.
    Inventors: Tai-Lai Tung, Mike Tu
  • Substituted Heteroaryls
    Publication number: 20100063063
    Abstract: The present invention provides Formula (1A) compounds that act as glucokinase activators; pharmaceutical compositions thereof; and methods of treating diseases, disorders, or conditions mediated by glucokinase. X, Y, Z, R1, R2, R3, and R4 are as described herein.
    Type: Application
    Filed: September 9, 2009
    Publication date: March 11, 2010
    Inventors: John William Benbow, Jihong Lou, Jeffrey Allen Pfefferkorn, Meihua Mike Tu
  • Reduced complexity time-frequency trained equalizer for discrete multi-tone based DSL systems
    Patent number: 7212595
    Abstract: The present invention provides a system and method for implementing a new TEQ training approach that trains TEQ coefficients by exploiting both time-domain and frequency-domain information. An advantage of this technique is that it reduces memory usage due to the training process. In addition, the complexity of the training process is simplified, and the associated computational work is reduced. The reduction of memory usage and computational work in turn may lead to cost savings, power consumption savings and other advantages.
    Type: Grant
    Filed: April 8, 2003
    Date of Patent: May 1, 2007
    Assignee: Conexant, Inc.
    Inventors: Tai-Lai Tung, Mike Tu
  • Systems and methods for resolving signal-to-noise ratio margin difference in dual latency discrete multi-tone-based xDSL systems under colored noise conditions
    Publication number: 20070047633
    Abstract: Systems and methods for resolving signal-to-noise ratio margin difference n dual latency discrete multi-tone (DMT)-based xDSL systems under colored noise conditions. Rather than assuming a constant power spectral density (PSD) for noise over fast and interleaved data paths of a dual latency system, band edges vulnerable to colored noise are determined and data on the fast data path is allocated away from these band edges. Also, receive windowing may be used to further enhance performance.
    Type: Application
    Filed: August 31, 2006
    Publication date: March 1, 2007
    Applicant: Conexant Systems, Inc.
    Inventors: Tai-Lai Tung, Mike Tu
  • Reduced complexity time-frequency trained equalizer for discrete multi-tone based DSL systems
    Publication number: 20040202260
    Abstract: The present invention provides a system and method for implementing a new TEQ training approach that trains TEQ coefficients by exploiting both time-domain and frequency-domain information. An advantage of this technique is that it reduces memory usage due to the training process. In addition, the complexity of the training process is simplified, and the associated computational work is reduced. The reduction of memory usage and computational work in turn may lead to cost savings, power consumption savings and other advantages.
    Type: Application
    Filed: April 8, 2003
    Publication date: October 14, 2004
    Inventors: Tai-Lai Tung, Mike Tu