Patents by Inventor Mike Whitney

Mike Whitney has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240124523
    Abstract: The present invention provides methods for guiding preservation of human neurons or human nerves during surgery by administering a fluorescently-labeled peptide that specifically binds to the human neurons or human nerves. The invention further provides human neuron or nerve targeting molecules comprising fluorescently-labeled peptides that specifically bind to human neurons or human nerves and compositions thereof.
    Type: Application
    Filed: August 30, 2023
    Publication date: April 18, 2024
    Inventors: Quyen T. Nguyen, Mike Whitney, Dina Hingorani, Roger Y. Tsien, Stephen Adams
  • Patent number: 11802138
    Abstract: The present invention provides methods for guiding preservation of human neurons or human nerves during surgery by administering a fluorescently-labeled peptide that specifically binds to the human neurons or human nerves. The invention further provides human neuron or nerve targeting molecules comprising fluorescently-labeled peptides that specifically bind to human neurons or human nerves and compositions thereof.
    Type: Grant
    Filed: May 21, 2021
    Date of Patent: October 31, 2023
    Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Quyen T. Nguyen, Mike Whitney, Dina Hingorani, Roger Y. Tsien, Stephen Adams
  • Patent number: 11299515
    Abstract: The present invention provides methods for guiding preservation of human neurons or human nerves during surgery by administering a fluorescently-labeled peptide that specifically binds to the human neurons or human nerves. The invention further provides human neuron or nerve targeting molecules comprising fluorescently-labeled peptides that specifically bind to human neurons or human nerves and compositions thereof.
    Type: Grant
    Filed: August 2, 2018
    Date of Patent: April 12, 2022
    Assignee: The Regents of the University of California
    Inventors: Quyen T. Nguyen, Mike Whitney, Dina Hingorani, Roger Y. Tsien, Stephen Adams
  • Publication number: 20210363186
    Abstract: The present invention provides methods for guiding preservation of human neurons or human nerves during surgery by administering a fluorescently-labeled peptide that specifically binds to the human neurons or human nerves. The invention further provides human neuron or nerve targeting molecules comprising fluorescently-labeled peptides that specifically bind to human neurons or human nerves and compositions thereof.
    Type: Application
    Filed: May 21, 2021
    Publication date: November 25, 2021
    Inventors: Quyen T. Nguyen, Mike Whitney, Dina Hingorani, Roger Y. Tsien, Stephen Adams
  • Patent number: 11021517
    Abstract: The present invention provides methods for guiding preservation of human neurons or human nerves during surgery by administering a fluorescently-labeled peptide that specifically binds to the human neurons or human nerves. The invention further provides human neuron or nerve targeting molecules comprising fluorescently-labeled peptides that specifically bind to human neurons or human nerves and compositions thereof.
    Type: Grant
    Filed: February 3, 2020
    Date of Patent: June 1, 2021
    Assignee: The Regents of the University of California
    Inventors: Quyen T. Nguyen, Mike Whitney, Dina Hingorani, Roger Y. Tsien, Stephen Adams
  • Publication number: 20200239522
    Abstract: The present invention provides methods for guiding preservation of human neurons or human nerves during surgery by administering a fluorescently-labeled peptide that specifically binds to the human neurons or human nerves. The invention further provides human neuron or nerve targeting molecules comprising fluorescently-labeled peptides that specifically bind to human neurons or human nerves and compositions thereof.
    Type: Application
    Filed: February 3, 2020
    Publication date: July 30, 2020
    Inventors: Quyen T. Nguyen, Mike Whitney, Dina Hingorani, Roger Y. Tsien, Stephen Adams
  • Patent number: 10385380
    Abstract: Disclosed herein, the invention pertains to methods and compositions that find use in diagnostic, prognostic and characterization of neoplasia samples based on the ability of a neoplasia sample to cleave a MTS molecule of the present invention. In some embodiments, a MTS molecule disclosed herein has the formula (A-X-B-C), wherein A is a peptide with a sequence comprising 5 to 9 consecutive acidic amino acids, wherein the amino acids are selected from: aspartates and glutamates; B is a peptide with a sequence comprising 5 to 20 consecutive basic amino acids; X is a linker; and C is a detectable moiety.
    Type: Grant
    Filed: October 2, 2015
    Date of Patent: August 20, 2019
    Assignee: The Regents of the University of California
    Inventors: Mike Whitney, Quyen T. Nguyen, Roger Y. Tsien
  • Publication number: 20160160263
    Abstract: Disclosed herein, the invention pertains to methods and compositions that find use in diagnostic, prognostic and characterization of neoplasia samples based on the ability of a neoplasia sample to cleave a MTS molecule of the present invention. In some embodiments, a MTS molecule disclosed herein has the formula (A-X-B-C), wherein A is a peptide with a sequence comprising 5 to 9 consecutive acidic amino acids, wherein the amino acids are selected from: aspartates and glutamates; B is a peptide with a sequence comprising 5 to 20 consecutive basic amino acids; X is a linker; and C is a detectable moiety.
    Type: Application
    Filed: October 2, 2015
    Publication date: June 9, 2016
    Inventors: Mike Whitney, Quyen T. Nguyen, Roger Y. Tsien
  • Publication number: 20120134922
    Abstract: Disclosed herein, in certain embodiments, is a selective transport molecule with increased in vivo circulation. In some embodiments, a selective transport molecule disclosed herein has the formula (A—X—B—C)n—M, wherein C is a cargo moiety; A is a peptide with a sequence comprising 5 to 9 consecutive acidic amino acids, wherein the amino acids are selected from: aspartates and glutamates; B is a peptide with a sequence comprising 5 to 20 consecutive basic amino acids; X is a linker; and M is a macromolecular carrier.
    Type: Application
    Filed: July 15, 2010
    Publication date: May 31, 2012
    Applicant: The Regents of the University of California
    Inventors: Roger Tsien, Emilia Olson, Tao Jiang, Quyen Nguyen, Mike Whitney
  • Patent number: 7967497
    Abstract: The present invention sets forth an implement which enables the user to mix paint, and optionally to perform several other painting related functions. The implement has a perforated paddle with oppositely deflected upper portions to enhance mixing of the paint. The implement may be selectively positionable to either mix paint or to support a paint roller for cleaning. A paint can remover and a paint can rim cleaning device are also incorporated into the implement. A single implement can serve the functions of opening paint cans, stirring paint in a container, cleaning the groove around the lip of a paint can, cleaning a paint roller, and as a spatula to aid in removing paint from a can.
    Type: Grant
    Filed: April 19, 2007
    Date of Patent: June 28, 2011
    Inventor: Mike Whitney
  • Publication number: 20070183255
    Abstract: The present invention sets forth an implement which enables the user to mix paint, and optionally to perform several other painting related functions. The implement has a perforated paddle with oppositely deflected upper portions to enhance mixing of the paint. The implement may be selectively positionable to either mix paint or to support a paint roller for cleaning. A paint can remover and a paint can rim cleaning device are also incorporated into the implement. A single implement can serve the functions of opening paint cans, stirring paint in a container, cleaning the groove around the lip of a paint can, cleaning a paint roller, and as a spatula to aid in removing paint from a can.
    Type: Application
    Filed: April 19, 2007
    Publication date: August 9, 2007
    Inventor: Mike Whitney
  • Patent number: 7229206
    Abstract: The present invention sets forth an implement which enables the user to mix paint, clean the can and can lip, and to clean conventional paint rollers utilizing a hand drill. The implement is selectively adjustable to be configured to mix paint in large and small containers and to support a paint roller for cleaning, thereby being capable of providing several functions. The implement is provided with a paddle member that is perforated and of a geometric form to enhance mixing. A paint can remover and a paint can rim cleaning device are also incorporated into the implement. A single implement serves the six functions of opening paint cans, stirring paint in large or small containers, cleaning the groove around the lip of a paint can, cleaning a paint roller, and as a spatula to aid in removing paint from a can.
    Type: Grant
    Filed: August 24, 2004
    Date of Patent: June 12, 2007
    Inventor: Mike Whitney
  • Publication number: 20050018533
    Abstract: The present invention sets forth an implement which enables the user to mix paint, clean the can and can lip, and to clean conventional paint rollers utilizing a hand drill. The implement is selectively adjustable to be configured to mix paint in large and small containers and to support a paint roller for cleaning, thereby being capable of providing several functions. The implement is provided with a paddle member that is perforated and of a geometric form to enhance mixing. A paint can remover and a paint can rim cleaning device are also incorporated into the implement. A single implement serves the six functions of opening paint cans, stirring paint in large or small containers, cleaning the groove around the lip of a paint can, cleaning a paint roller, and as a spatula to aid in removing paint from a can.
    Type: Application
    Filed: August 24, 2004
    Publication date: January 27, 2005
    Inventor: Mike Whitney
  • Publication number: 20030053838
    Abstract: The present invention sets forth a painting implement which enables the user to mix paint and to clean conventional paint rollers utilizing a hand drill. The painting implement is selectively adjustable to be configured to mix paint and to support a paint roller for cleaning, thereby being capable of providing several functions. Implements of different diameters may be provided, for cleaning and using an assortment of sizes of paint rollers. The implement is provided with a paddle member that is perforated and of a geometric wave-like form to enhance mixing.
    Type: Application
    Filed: October 30, 2002
    Publication date: March 20, 2003
    Inventor: Mike Whitney
  • Patent number: 6520672
    Abstract: A kit of painting accessories enabling a user to clean paint rollers and brushes by spinning them with a hand drill, and to mix paint utilizing a hand drill. The kit includes an element for grasping paint brushes, a paint roller holder, a drive adapter enabling the aforementioned kit components to be mounted on a hand drill and rotatably driven thereby, and a paint mixer having a shaft insertable into the chuck of the hand drill. The paddle of the paint mixer can be adjusted between two positions selectively enabling the mixer to mix paint and to receive a paint roller for cleaning by spinning.
    Type: Grant
    Filed: July 21, 2000
    Date of Patent: February 18, 2003
    Inventor: Mike Whitney