Patents by Inventor Mikhail Denissenko

Mikhail Denissenko has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and methods for treatment of cachexia
    Patent number: 8080528
    Abstract: Compositions and methods for preventing and treating wasting disorders, such as cachexia and anorexia, are provided. In one aspect, the present invention provides a method for preventing and treating a wasting disorder in a mammal. In one embodiment, the method of the invention comprises administering to such mammal a macrolide and a ?2-adrenergic agonist in combination such that the macrolide and said ?2-agonist are administered in amounts effective to prevent or at least alleviate said wasting disorder.
    Type: Grant
    Filed: December 20, 2006
    Date of Patent: December 20, 2011
    Assignee: The Releef Initiative
    Inventors: Richard Kenley, Jonas Ekblom, Mikhail Denissenko
  • Compositions and Methods for Treatment of Exudative Serous Effusion
    Publication number: 20090221518
    Abstract: Compositions and methods are provided for treating accumulation of exudative serous effusions caused by illnesses such as cancer, infection, and pancreatitis. In one embodiment, the method of the invention comprises administering to such mammal a macrolide in an amount effective to prevent or at least alleviate said exudative serous effusion accumulation.
    Type: Application
    Filed: September 5, 2008
    Publication date: September 3, 2009
    Applicant: Anaborex, Inc.
    Inventors: Richard Kenley, Mikhail Denissenko
  • COMPOSITIONS AND METHODS FOR PREVENTION AND TREATMENT OF CACHEXIA
    Publication number: 20070149465
    Abstract: Compositions and methods for preventing and treating wasting disorders, such as cachexia and anorexia, are provided. In one aspect, the present invention provides a method for preventing and treating a wasting disorder in a mammal. In one embodiment, the method of the invention comprises administering to such mammal a macrolide and a ?2-adrenergic agonist in combination such that the macrolide and said ?2-agonist are administered in amounts effective to prevent or at least alleviate said wasting disorder.
    Type: Application
    Filed: December 20, 2006
    Publication date: June 28, 2007
    Inventors: Richard Kenley, Jonas Ekblom, Mikhail Denissenko
  • Methods for identifying risk of breast cancer and treatments thereof
    Publication number: 20050118606
    Abstract: Provided herein are methods for identifying a risk of cancer in a subject and/or a subject at risk of cancer, reagents and kits for carrying out the methods, methods for identifying candidate therapeutics for treating cancer, and therapeutic methods for treating cancer in a subject. These embodiments are based upon an analysis of polymorphic variations in a KLF12 nucleic acid, which has a nucleotide sequence exemplified in SEQ ID NO: 1, 2 or 3.
    Type: Application
    Filed: November 25, 2003
    Publication date: June 2, 2005
    Inventors: Richard Roth, Caridad Rosette, Mikhail Denissenko, Matthew Nelson, Rikard Reneland, Andreas Braun, Stefan Kammerer
  • Methods for identifying risk of breast cancer and treatments thereof
    Publication number: 20050064442
    Abstract: Provided herein are methods for identifying a subject at risk of breast cancer, reagents and kits for carrying out the methods, methods for identifying candidate therapeutics for treating breast cancer, and therapeutic methods for treating breast cancer in a subject. These embodiments are based upon an analysis of polymorphic variations in nucleotide sequences within the human genome.
    Type: Application
    Filed: November 25, 2003
    Publication date: March 24, 2005
    Inventors: Richard Roth, Josephine Atienza, Mikhail Denissenko, Andreas Braun, Stefan Kammerer, Matthew Nelson, Rikard Reneland
  • Therapeutic methods for reducing fat deposition and treating associated conditions
    Publication number: 20050014158
    Abstract: Provided herein are methods for prognosing and diagnosing fat deposition and related disorders (e.g., obesity and non-insulin diabetes dependent mellitus (NIDDM)) in a subject, reagents and kits for carrying out the methods, methods for identifying candidate therapeutics for reducing fat deposition and related disorders, and therapeutic methods for reducing fat deposition or treating fat deposition related disorders in a subject. These embodiments are based in part upon an analysis of polymorphic variations of the nucleic acid set forth in SEQ ID NO:1.
    Type: Application
    Filed: June 27, 2003
    Publication date: January 20, 2005
    Inventors: Gail Adam, Maria Langdown, Mikhail Denissenko, Edward Dennis, Charles Cantor, Byron Rubin