Patents by Inventor Mikhail Fedorovich Gordeev

Mikhail Fedorovich Gordeev has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOUNDS AND COMPOSITIONS FOR TARGETED THERAPY OF RENAL DISEASES
    Publication number: 20250109171
    Abstract: Provided herein are therapeutic compounds, for example compounds of Formula I, or pharmaceutically acceptable salts, hydrates, or solvates thereof that are therapeutic or anticancer agents, pharmaceutical compositions thereof, methods for their use, and methods for preparing these compounds.
    Type: Application
    Filed: July 21, 2022
    Publication date: April 3, 2025
    Inventors: Mikhail Fedorovich Gordeev, Jinqian Liu, Xinghai Wang
  • Pharmaceutical crystal of contezolid acefosamil, preparation method therefor, and uses thereof
    Patent number: 12180242
    Abstract: The present invention relates to a pharmaceutical crystal of contezolid acefosamil, a preparation method therefor, and uses thereof. The present invention also relates to a crystal or crystal complex of formula I, wherein R is selected from hydrogen, sodium or a mixture thereof in any ratio.
    Type: Grant
    Filed: September 29, 2019
    Date of Patent: December 31, 2024
    Assignee: SHANGHAI MICURX PHARMACEUTICAL CO., LTD
    Inventors: Xueliang Zhang, Xinghai Wang, Jinqian Liu, Mikhail Fedorovich Gordeev
  • NOVEL COMPOUNDS AND COMPOSITIONS FOR TARGETED THERAPY OF RENAL CANCERS
    Publication number: 20240376155
    Abstract: Provided are therapeutic compounds, for example compounds of Formula I, or pharmaceutically acceptable salts, hydrates, or solvates thereof that are therapeutic or anticancer agents, pharmaceutical compositions thereof, methods for their use, and methods for preparing these compounds.
    Type: Application
    Filed: July 21, 2022
    Publication date: November 14, 2024
    Inventors: Mikhail Fedorovich Gordeev, Jinqian Liu, Shouning Xu, Xinghai Wang
  • PRODRUGS OF BORON COMPOUNDS AND THEIR USE IN TREATING BACTERIAL INFECTIONS
    Publication number: 20240279247
    Abstract: Described herein are prodrugs of antimicrobial organoboron compounds of Formula I, or salts thereof, and pharmaceutical compositions thereof, methods for their use, and methods for preparing the same.
    Type: Application
    Filed: March 14, 2024
    Publication date: August 22, 2024
    Inventors: Xinghai Wang, Jinqian Liu, Mikhail Fedorovich Gordeev
  • METHODS AND USES OF BORON COMPOUNDS IN THE TREATMENT OF NONTUBERCULOUS MYCOBACTERIUM INFECTIONS AND PHARMACEUTICAL COMPOSITIONS FOR TREATMENT OF SAME
    Publication number: 20240269155
    Abstract: Provided herein are organoboron compounds of Formula I, or salts thereof, and pharmaceutical compositions and the use of organoboron compounds and pharmaceutical compositions for the treatment of nontuberculous Mycobacterium infections.
    Type: Application
    Filed: March 14, 2024
    Publication date: August 15, 2024
    Inventors: Xinghai Wang, Shicong Liu, Jinqian Liu, Mikhail Fedorovich Gordeev, Zhengyu Yuan
  • NOVEL COMPOUNDS AND COMPOSITION FOR TARGETED THERAPY OF KIDNEY-ASSOCIATED CANCERS
    Publication number: 20230141981
    Abstract: The present invention provides therapeutic compounds of the following formula I: or pharmaceutically acceptable salts, hydrates, or solvates thereof that are therapeutic or anticancer agents, pharmaceutical compositions containing them, methods for their use, and methods for preparing these compounds.
    Type: Application
    Filed: January 21, 2021
    Publication date: May 11, 2023
    Inventors: Mikhail Fedorovich GORDEEV, Jinqian LIU
  • PHARMACEUTICAL CRYSTAL OF CONTEZOLID ACEFOSAMIL, PREPARATION METHOD THEREFOR, AND USES THEREOF
    Publication number: 20220153767
    Abstract: The present invention relates to a pharmaceutical crystal of contezolid acefosamil, a preparation method therefor, and uses thereof. The present invention also relates to a crystal or crystal complex of formula I, wherein R is selected from hydrogen, sodium or a mixture thereof in any ratio.
    Type: Application
    Filed: September 29, 2019
    Publication date: May 19, 2022
    Inventors: Xueliang ZHANG, Xinghai WANG, Jinqian LIU, Mikhail Fedorovich GORDEEV
  • Antimicrobial polymyxins for treatment of bacterial infections
    Patent number: 9771394
    Abstract: The present invention provides antimicrobial polymyxin compounds of the following formula I: or pharmaceutically acceptable salts, hydrates, or solvates thereof that are antibacterial agents, pharmaceutical compositions containing them, methods for their use, and methods for preparing these compounds.
    Type: Grant
    Filed: December 16, 2015
    Date of Patent: September 26, 2017
    Assignee: MICURX PHARMACEUTICALS, INC.
    Inventors: Mikhail Fedorovich Gordeev, Jinqian Liu, Xinghai Wang, Zhengyu Yuan
  • Water-soluble O-carbonyl phosphoramidate prodrugs for therapeutic administration
    Patent number: 9382276
    Abstract: The present invention provides certain water-soluble O-carbonyl phosphoramidate prodrugs of the following formula I: or pharmaceutically acceptable salts thereof that are therapeutic or antibacterial agents, pharmaceutical compositions containing them, methods for their use, and reagents and methods for preparing these compounds.
    Type: Grant
    Filed: February 20, 2015
    Date of Patent: July 5, 2016
    Assignee: MicuRx Pharmaceuticals, Inc.
    Inventors: Mikhail Fedorovich Gordeev, Jinqian Liu, Xinghai Wang, Zhengyu Yuan
  • ANTIMICROBIAL POLYMYXINS FOR TREATMENT OF BACTERIAL INFECTIONS
    Publication number: 20160185823
    Abstract: The present invention provides antimicrobial polymyxin compounds of the following formula I: or pharmaceutically acceptable salts, hydrates, or solvates thereof that are antibacterial agents, pharmaceutical compositions containing them, methods for their use, and methods for preparing these compounds.
    Type: Application
    Filed: December 16, 2015
    Publication date: June 30, 2016
    Inventors: Mikhail Fedorovich GORDEEV, Jinqian LIU
  • WATER-SOLUBLE O-CARBONYL PHOSPHORAMIDATE PRODRUGS FOR THERAPEUTIC ADMINISTRATION
    Publication number: 20150239922
    Abstract: The present invention provides certain water-soluble O-carbonyl phosphoramidate prodrugs of the following formula I: or pharmaceutically acceptable salts thereof that are therapeutic or antibacterial agents, pharmaceutical compositions containing them, methods for their use, and reagents and methods for preparing these compounds.
    Type: Application
    Filed: February 20, 2015
    Publication date: August 27, 2015
    Inventors: Mikhail Fedorovich GORDEEV, Jinqian LIU, Xinghai WANG, Zhengyu YUAN
  • Tricyclic boron compounds for antimicrobial therapy
    Patent number: 8530452
    Abstract: Provided herein are antimicrobial tricyclic boron compounds of the following formula I: or pharmaceutically acceptable salts, complexes, or tautomers thereof that are antibacterial agents, pharmaceutical compositions containing them, methods for their use, and methods for preparing these compounds.
    Type: Grant
    Filed: December 20, 2012
    Date of Patent: September 10, 2013
    Assignee: MicuRx Pharmaceuticals, Inc.
    Inventors: Mikhail Fedorovich Gordeev, Jinqian Liu, Zhengyu Yuan, Xinghai Wang
  • ANTIMICROBIAL ORTHO-FLUOROPHENYL OXAZOLIDINONES FOR TREATMENT OF BACTERIAL INFECTIONS
    Publication number: 20120190713
    Abstract: The present invention provides certain ortho-fluorophenyl oxazolidinones of the following formula I: or pharmaceutically acceptable salts or prodrugs thereof that are antibacterial agents, pharmaceutical compositions containing them, methods for their use, and methods for preparing these compounds.
    Type: Application
    Filed: April 3, 2012
    Publication date: July 26, 2012
    Inventor: Mikhail Fedorovich Gordeev
  • Antimicrobial heterocyclic compounds for treatment of bacterial infections
    Publication number: 20120157434
    Abstract: The present invention provides heterocyclic compounds of the following formula I: or pharmaceutically acceptable salts, prodrugs, solvates, or hydrates thereof useful as antibacterial agents, pharmaceutical compositions containing them, methods for their use, and methods for preparing these compounds.
    Type: Application
    Filed: February 29, 2008
    Publication date: June 21, 2012
    Inventors: Mikhail Fedorovich Gordeev, Zhengyu Yuan, Jinqian Liu
  • Antimicrobial ortho-fluorophenyl oxazolidinones for treatment of bacterial infections
    Patent number: 8178683
    Abstract: The present invention provides certain ortho-fluorophenyl oxazolidinones of the following formula I: or pharmaceutically acceptable salts or prodrugs thereof that are antibacterial agents, pharmaceutical compositions containing them, methods for their use, and methods for preparing these compounds.
    Type: Grant
    Filed: August 6, 2008
    Date of Patent: May 15, 2012
    Assignee: Micurx Pharmaceuticals, Inc.
    Inventor: Mikhail Fedorovich Gordeev
  • Antimicrobial Cyclocarbonyl Heterocyclic Compounds For Treatment Of Bacterial Infections
    Publication number: 20120065170
    Abstract: The present invention provides indoline compounds of the following formula I: or pharmaceutically acceptable salts, prodrugs, solvates, or hydrates thereof useful as antibacterial agents, pharmaceutical compositions containing them, methods for their use, and methods for preparing these compounds.
    Type: Application
    Filed: September 8, 2011
    Publication date: March 15, 2012
    Inventors: Mikhail Fedorovich Gordeev, Jinqian Liu, Qiang Wang, Li Zhang
  • N-hydroxyamide derivatives possessing antibacterial activity
    Patent number: 8088804
    Abstract: Described herein are N-hydroxyamide antibacterial compounds, methods for making the compounds, pharmaceutical compositions containing the compounds and methods of treating bacterial infections utilizing the compounds and pharmaceutical compositions compound of Formula (I): or a salt, solvate ti hydrate thereof, wherein A is (a) each indicates a point of attachment.
    Type: Grant
    Filed: December 4, 2006
    Date of Patent: January 3, 2012
    Assignee: Pfizer Inc.
    Inventors: Rakesh Kumar Jain, Mikhail Fedorovich Gordeev, Jason Gustaf Lewis, Charles Francavilla
  • Methods and Processes For Syntheses and Manufacture of Antimicrobial 1(Ortho-Fluorophenyl)dihydropyridones
    Publication number: 20100204477
    Abstract: Provided herein are methods and processes for synthesis and manufacture of compounds of formula I: or its crystal forms, pharmaceutical acceptable salts, prodrugs, hydrates, or solvates thereof.
    Type: Application
    Filed: February 5, 2010
    Publication date: August 12, 2010
    Inventors: Qiang Wang, Feng Zhou, Jinqian Liu, Mikhail Fedorovich Gordeev
  • ANTIMICROBIAL INDOLINE COMPOUNDS FOR TREATMENT OF BACTERIAL INFECTIONS
    Publication number: 20100069441
    Abstract: The present invention provides indoline heterocyclic compounds of the following formula I: or pharmaceutically acceptable salts, prodrugs, solvates, or hydrates thereof useful as antibacterial agents, pharmaceutical compositions containing them, methods for their use, and methods for preparing these compounds.
    Type: Application
    Filed: September 1, 2009
    Publication date: March 18, 2010
    Inventors: Mikhail Fedorovich Gordeev, Zhengyu Yuan, Jinqian Liu, Qiang Wang
  • N-HYDROXYAMIDE DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY
    Publication number: 20100022605
    Abstract: Described herein are N-hydroxyamlde antibacterial compounds, methods for making the compounds, pharmaceutical compositions containing the compounds and methods of treating bacterial infections utilizing the compounds and pharmaceutical compositions compound of Formula (I): or a salt, solvate ti hydrate thereof, wherein A is (a) eachindicates a point of attachment.
    Type: Application
    Filed: December 4, 2006
    Publication date: January 28, 2010
    Inventors: Rakesh Kumar Jain, Mikhail Fedorovich Gordeev, Jason Gustaf Lewis, Charles Francavilla