Patents by Inventor Mikhail L. Papisov

Mikhail L. Papisov has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Conjugates Comprising a Biodegradable Polymer and Uses Therefor
    Publication number: 20110044967
    Abstract: Biologically active agents covalently linked to a polymer. The polymer is preferably a biodegradable polymer are provided. The biologically active agent is preferably a protein, such as an extracellular soluble protein, e.g., an extracellular enzyme. The enzyme can be an apyrase, e.g., NTPDase. Conjugates of the invention can be used as therapeutics in subjects. For example, a conjugate comprising an apyrase can be used for treating and preventing thrombosis, atherosclerotic plaque complications and vascular disorders.
    Type: Application
    Filed: August 27, 2010
    Publication date: February 24, 2011
    Inventors: DAVID R. ELMALEH, SIMON C. ROBSON, MIKHAIL L. PAPISOV
  • Conjugates comprising a biodegradable polymer and uses therefor
    Patent number: 7785618
    Abstract: Biologically active agents covalently linked to a polymer. The polymer is preferably a biodegradable polymer are provided. The biologically active agent is preferably a protein, such as an extracellular soluble protein, e.g., an extracellular enzyme. The enzyme can be an apyrase, e.g., NTPDase. Conjugates of the invention can be used as therapeutics in subjects. For example, a conjugate comprising an apyrase can be used for treating and preventing thrombosis, atherosclerotic plaque complications and vascular disorders.
    Type: Grant
    Filed: August 20, 2004
    Date of Patent: August 31, 2010
    Inventors: David R. Elmaleh, Simon C. Robson, Mikhail L. Papisov