Patents by Inventor Mikhail Martchenko

Mikhail Martchenko has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Inhibition of multiple pathogenic agents using bithionol
    Patent number: 10369119
    Abstract: Compositions and methods including Bithionol are provided for treating, inhibiting, or preventing caspase-dependent pathogenic agents in a host cell or infected subject. Examples of caspase-dependent pathogenic agents include ricin, anthrax toxin, Botulinum neurotoxin A, diphtheria toxin, Pseudomonas aeruginosa exotoxin A, cholera toxin, Zika virus, and combinations thereof. Compositions and methods also include Bithionol in combination with an antibiotic for more effective clearance of the pathogen and/or toxins.
    Type: Grant
    Filed: October 21, 2016
    Date of Patent: August 6, 2019
    Assignee: Keck Graduate Institute of Applied Life Sciences
    Inventors: Mikhail Martchenko, William Leonardi
  • INHIBITION OF MULTIPLE PATHOGENIC AGENTS USING BITHIONOL
    Publication number: 20180303769
    Abstract: Compositions and methods including Bithionol are provided for treating, inhibiting, or preventing caspase-dependent pathogenic agents in a host cell or infected subject. Examples of caspase-dependent pathogenic agents include ricin, anthrax toxin, Botulinum neurotoxin A, diphtheria toxin, Pseudomonas aeruginosa exotoxin A, cholera toxin, Zika virus, and combinations thereof. Compositions and methods also include Bithionol in combination with an antibiotic for more effective clearance of the pathogen and/or toxins.
    Type: Application
    Filed: October 21, 2016
    Publication date: October 25, 2018
    Applicant: KECK GRADUATE INSTOTUTE OF APPLIED LIFE SCIENCES
    Inventors: Mikhail Martchenko, William Leonardi
  • Compositions and methods for inhibiting bacterial and viral pathogens
    Patent number: 10039758
    Abstract: Compositions and methods including Amodiaquine (AQ) or N-Desethy Amodiaquine (DEAQ) are provided for treating, inhibiting, or preventing cathepsin B dependent pathogens and toxins in a host cell or infected subject. Compositions and methods also include AQ or DEAQ in combination with an antibiotic for more effective clearance of the pathogen and/or toxins.
    Type: Grant
    Filed: October 23, 2015
    Date of Patent: August 7, 2018
    Assignee: Keck Graduate Institute of Applied Life Sciences
    Inventors: Mikhail Martchenko, Leeor Zilbermintz, William Leonardi
  • Method of treating microbial infections
    Patent number: 9439876
    Abstract: Methods of inhibiting or preventing the proliferation of a fungus and/or a bacteria in a living organism, in water, in air, and/or on surfaces, include administering or providing a therapeutic amount or an effective amount of an antimicrobial composition including Octodrine.
    Type: Grant
    Filed: January 13, 2014
    Date of Patent: September 13, 2016
    Assignee: KECK GRADUATE INSTITUTE OF APPLIED LIFE SCIENCES
    Inventors: Mikhail Martchenko, Kevin Jee Kim
  • COMPOSITIONS AND METHODS FOR INHIBITING BACTERIAL AND VIRAL PATHOGENS
    Publication number: 20160113920
    Abstract: Compositions and methods including Amodiaquine (AQ) or N-Desethy Amodiaquine (DEAQ) are provided for treating, inhibiting, or preventing cathepsin B dependent pathogens and toxins in a host cell or infected subject. Compositions and methods also include AQ or DEAQ in combination with an antibiotic for more effective clearance of the pathogen and/or toxins.
    Type: Application
    Filed: October 23, 2015
    Publication date: April 28, 2016
    Inventors: Mikhail MARTCHENKO, Leeor ZILBERMINTZ, Sun-Young Jeong
  • METHOD OF TREATING MICROBIAL INFECTIONS
    Publication number: 20150196499
    Abstract: Methods of inhibiting or preventing the proliferation of a fungus and/or a bacteria in a living organism, in water, in air, and/or on surfaces, include administering or providing a therapeutic amount or an effective amount of an antimicrobial composition including Octodrine.
    Type: Application
    Filed: January 13, 2014
    Publication date: July 16, 2015
    Applicant: KECK GRADUATE INSTITUTE OF APPLIED LIFE SCIENCES
    Inventors: Mikhail Martchenko, Kevin Jee Kim