Patents by Inventor Mikhail Rekharsky

Mikhail Rekharsky has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for determining quantity of peptide compound having phenylalanine residue at N-terminus
    Patent number: 8168436
    Abstract: The present invention provides a method for quantifying a peptide compound having a phenylalanine residue at the N-terminal, comprising measuring the content of heat generated by mixing 1) a peptide compound having a phenylalanine residue at the N-terminal, 2) cucurbit[7]uril, and 3) a metal ion in a solution.
    Type: Grant
    Filed: October 23, 2007
    Date of Patent: May 1, 2012
    Assignee: Japan Science and Technology Agency
    Inventors: Yoshihisa Inoue, Mikhail Rekharsky, Kimoon Kim, Yong Ho Ko, Narayanan Selvapalam
  • Method for determination of presence or absence of peptide compound PYY
    Patent number: 7993929
    Abstract: The present invention provides a method for determining in a pharmaceutical test formulation the presence or absence of a peptide compound PYY3-36 represented by the following amino acid sequence: H-Ile-Lys-Pro-Glu-Ala-Pro-Gly-Glu-Asp-Ala-Ser-Pro-Glu-Glu-Leu-Asn-Arg-Tyr-Tyr-Ala-Ser-Leu-Arg-His-Tyr-Leu-Asn-Leu-Val-Thr-Arg-Gln-Arg-Tyr-X (SEQ ID NO: 1), wherein X is OH or a carboxy acid-protecting group, the method comprising (1) preparing a solution by mixing the pharmaceutical test formulation with cucurbit[7]uril in a solvent; and (2) thermally analyzing the solution prepared in Step (1).
    Type: Grant
    Filed: May 11, 2009
    Date of Patent: August 9, 2011
    Assignee: Japan Science and Technology Agency
    Inventors: Yoshihisa Inoue, Mikhail Rekharsky, Kimoon Kim, Yong Ho Ko, Narayanan Selvapalam
  • METHOD FOR DETERMINATION OF PRESENCE OR ABSENCE OF PEPTIDE COMPOUND PYY3-36
    Publication number: 20100281957
    Abstract: The present invention provides a method for determining in a pharmaceutical test formulation the presence or absence of a peptide compound PYY3-36 represented by the following amino acid sequence: H-Ile-Lys-Pro-Glu-Ala-Pro-Gly-Glu-Asp-Ala-Ser-Pro-Glu-Glu-Leu-Asn-Arg-Tyr-Tyr-Ala-Ser-Leu-Arg-His-Tyr-Leu-Asn-Leu-Val-Thr-Arg-Gln-Arg-Tyr-X (SEQ ID NO: 1), wherein X is OH or a carboxy acid-protecting group, the method comprising (1) preparing a solution by mixing the pharmaceutical test formulation with cucurbit[7]uril in a solvent; and (2) thermally analyzing the solution prepared in Step (1).
    Type: Application
    Filed: October 25, 2007
    Publication date: November 11, 2010
    Applicant: JAPAN SCIENCE AND TECHNOLOGY AGENCY
    Inventors: Yoshihisa Inoue, Mikhail Rekharsky, Kimoon Kim, Yong Ho Ko, Narayanan Selvapalam
  • METHOD FOR DETERMINING QUANTITY OF PEPTIDE COMPOUND HAVING PHENYLALANINE RESIDUE AT N-TERMINUS
    Publication number: 20100238969
    Abstract: The present invention provides a method for quantifying a peptide compound having a phenylalanine residue at the N-terminal, comprising measuring the content of heat generated by mixing 1) a peptide compound having a phenylalanine residue at the N-terminal, 2) cucurbit[7]uril, and 3) a metal ion in a solution.
    Type: Application
    Filed: October 23, 2007
    Publication date: September 23, 2010
    Applicant: JAPAN SCIENCE AND TECHNOLOGY AGENCY
    Inventors: Yoshihisa Inoue, Mikhail Rekharsky, Kimoon Kim, Yong Ho Ko, Narayanan Selvapalam
  • METHOD FOR DETERMINATION OF PRESENCE OR ABSENCE OF PEPTIDE COMPOUND PYY3-36
    Publication number: 20100009453
    Abstract: The present invention provides a method for determining in a pharmaceutical test formulation the presence or absence of a peptide compound PYY3-36 represented by the following amino acid sequence: H-Ile-Lys-Pro-Glu-Ala-Pro-Gly-Glu-Asp-Ala-Ser-Pro-Glu-Glu-Leu-Asn-Arg-Tyr-Tyr-Ala-Ser-Leu-Arg-His-Tyr-Leu-Asn-Leu-Val-Thr-Arg-Gln-Arg-Tyr-X (SEQ ID NO: 1), wherein X is OH or a carboxy acid-protecting group, the method comprising (1) preparing a solution by mixing the pharmaceutical test formulation with cucurbit[7]uril in a solvent; and (2) thermally analyzing the solution prepared in Step (1).
    Type: Application
    Filed: May 11, 2009
    Publication date: January 14, 2010
    Applicant: JAPAN SCIENCE AND TECHNOLOGY AGENCY
    Inventors: Yoshihisa INOUE, Mikhail REKHARSKY, Kimoon KIM, Yong Ho KO, Narayanan SELVAPALAM