Patents by Inventor Mikihiro Fujiya

Mikihiro Fujiya has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Intestinal protectant
    Patent number: 11752180
    Abstract: The present invention provides an intestinal tract protective agent comprising a polyphosphoric acid or a pharmaceutically acceptable salt thereof as an active ingredient.
    Type: Grant
    Filed: August 6, 2020
    Date of Patent: September 12, 2023
    Assignees: National University Corporation Asahikawa Medical University, Sapporo Holdings Limited
    Inventors: Yutaka Kohgo, Mikihiro Fujiya, Nobuhiro Ueno, Syuichi Segawa, Naoyuki Kobayashi
  • PLATELET AGGREGATING AGENT
    Publication number: 20220409655
    Abstract: The present invention relates to a platelet aggregating agent containing amorphous polyphosphate as an active ingredient, wherein the polyphosphate is a Ca salt of polyphosphate. The platelet aggregating agent acts on damaged gastrointestinal mucosa in inflammatory bowel disease and exerts a platelet aggregating action, thereby allowing remission/improvement of the inflammatory bowel disease.
    Type: Application
    Filed: January 7, 2021
    Publication date: December 29, 2022
    Inventors: Mikihiro FUJIYA, Hiroaki KONISHI, Hiroki TANAKA, Shotaro ISOZAKI, Yoshihiro OMACHI, Naoki OGAWA
  • Creation of peptide-based anti-tumor agent
    Patent number: 11384121
    Abstract: An object of the present invention is to provide an echinomycin derivative that has anti-cancer activity equal to or greater than that of echinomycin, and a production method therefor based on a chemical procedure. Provided are an echinomycin derivative represented by formula (I), and a production method therefor based on a chemical procedure.
    Type: Grant
    Filed: January 31, 2019
    Date of Patent: July 12, 2022
    Assignee: National University Corporation Hokkaido University
    Inventors: Satoshi Ichikawa, Keita Kojima, Mikihiro Fujiya, Hiroaki Konishi
  • CREATION OF PEPTIDE-BASED ANTI-TUMOR AGENT
    Publication number: 20210017232
    Abstract: An object of the present invention is to provide an echinomycin derivative that has anti-cancer activity equal to or greater than that of echinomycin, and a production method therefor based on a chemical procedure. Provided are an echinomycin derivative represented by formula (I), and a production method therefor based on a chemical procedure.
    Type: Application
    Filed: January 31, 2019
    Publication date: January 21, 2021
    Applicant: National University Corporation Hokkaido University
    Inventors: Satoshi ICHIKAWA, Keita KOJIMA, Mikihiro FUJIYA, Hiroaki KONISHI
  • Intestinal Protectant
    Publication number: 20200368299
    Abstract: The present invention provides an intestinal tract protective agent comprising a polyphosphoric acid or a pharmaceutically acceptable salt thereof as an active ingredient.
    Type: Application
    Filed: August 6, 2020
    Publication date: November 26, 2020
    Applicants: National University Corporation Asahikawa Medical University, Sapporo Holdings Limited
    Inventors: Yutaka Kohgo, Mikihiro Fujiya, Nobuhiro Ueno, Syuichi Segawa, Naoyuki Kobayashi
  • Intestinal protectant
    Patent number: 10792315
    Abstract: The present invention provides an intestinal tract protective agent comprising a polyphosphoric acid or a pharmaceutically acceptable salt thereof as an active ingredient.
    Type: Grant
    Filed: March 28, 2011
    Date of Patent: October 6, 2020
    Assignees: National University Corporation Asahikawa Medical University, Sapporo Holdings Limited
    Inventors: Yutaka Kohgo, Mikihiro Fujiya, Nobuhiro Ueno, Syuichi Segawa, Naoyuki Kobayashi
  • Antitumor agent
    Patent number: 10576126
    Abstract: [Problem] To provide a highly safe and efficacious antitumor agent that is derived from probiotics. [Solution] The present invention relates to an antitumor agent comprising a compound represented by formula (1) or a complex thereof as an active ingredient. In formula (1): R1 represents a hydrogen atom or a hydroxymethyl group; R2 represents a hydrogen atom, a methyl group or a hydroxymethyl group; and R3, R4 and R5 each independently represent a methyl group, an N5-(trans-5-hydroxy-3-methylpent-2-enoyl) group, an N5-(cis-5-hydroxy-3-methylpent-2-enoyl) group or an N5-(trans-4-carboxy-3-methylpent-2-enoyl) group. According to the present invention, a highly safe and efficacious antitumor agent can be provided.
    Type: Grant
    Filed: January 19, 2017
    Date of Patent: March 3, 2020
    Assignee: National University Corporation Asahikawa Medical University
    Inventors: Mikihiro Fujiya, Hiroaki Konishi, Kentaro Moriichi
  • ANTITUMOR AGENT
    Publication number: 20190022172
    Abstract: [Problem] To provide a highly safe and efficacious antitumor agent that is derived from probiotics. [Solution] The present invention relates to an antitumor agent comprising a compound represented by formula (1) or a complex thereof as an active ingredient. In formula (1): R1 represents a hydrogen atom or a hydroxymethyl group; R2 represents a hydrogen atom, a methyl group or a hydroxymethyl group; and R3, R4 and R5 each independently represent a methyl group, an N5-(trans-5-hydroxy-3-methylpent-2-enoyl) group, an N5-(cis-5-hydroxy-3-methylpent-2-enoyl) group or an N5-(trans-4-carboxy-3-methylpent-2-enoyl) group. According to the present invention, a highly safe and efficacious antitumor agent can be provided.
    Type: Application
    Filed: January 19, 2017
    Publication date: January 24, 2019
    Applicant: NATIONAL UNIVERSITY CORPORATION ASAHIKAWA MEDICAL MEDICAL
    Inventors: Mikihiro FUJIYA, Hiroaki KONISHI, Kentaro MORIICHI
  • INTESTINAL PROTECTANT
    Publication number: 20130171118
    Abstract: The present invention provides an intestinal tract protective agent comprising a polyphosphoric acid or a pharmaceutically acceptable salt thereof as an active ingredient.
    Type: Application
    Filed: March 28, 2011
    Publication date: July 4, 2013
    Applicants: SAPPORO BREWERIES LIMITED, National University Corporation ASAHIKAWA MEDICAL UNIVERSITY
    Inventors: Yutaka Kohgo, Mikihiro Fujiya, Nobuhiro Ueno, Syuichi Segawa, Naoyuki Kobayashi