Patents by Inventor Mikinaga MORI
Mikinaga MORI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20190314335Abstract: An object of the present invention is to provide a lipid particle composition containing panobinostat or a salt thereof and exhibiting a high bone marrow-targeting capability, and a pharmaceutical composition including the lipid particle composition. According to the present invention, provided is a lipid particle composition containing panobinostat or a salt thereof, in which a lipid particle contains a phospholipid and cholesterol.Type: ApplicationFiled: June 21, 2019Publication date: October 17, 2019Applicant: FUJIFILM CorporationInventors: Yuta YOSHINO, Hayato OGURA, Mikinaga MORI, Taisuke ENDO, Kentaro NUMAJIRI, Ritsuko HORI
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Patent number: 10391057Abstract: Provided are a liposome composition which has a practically required long-term preservation stability, and which has a release rate of a drug on the order of several tens of hours due to releasability of a drug being able to be suitably controlled by rendering an inner water phase hyper-osmotic; and a method for producing the same. According to the present invention, it is possible to provide a liposome composition, including liposomes each of which has an inner water phase and an aqueous solution which constitutes an outer water phase and in which the liposomes are dispersed, in which the content of cholesterols is 10 mol % to 35 mol % with respect to the total amount of lipid components in the liposome composition, and each of the liposomes encapsulates a drug in a dissolved state, and an osmotic pressure of the inner water phase is 2-fold to 8-fold relative to the osmotic pressure of the outer water phase.Type: GrantFiled: October 27, 2016Date of Patent: August 27, 2019Assignee: FUJIFILM CorporationInventors: Makoto Ono, Kohei Ono, Takeshi Matsumoto, Mikinaga Mori
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Publication number: 20180243215Abstract: An object of the present invention is to provide a liposome composition containing a liposome having an excellent leakage rate of a nucleic acid analog anticancer agent, and a method for producing the same. According to the present invention, there are provided a liposome composition containing a liposome which (1) contains a nucleic acid analog anticancer agent and in which (2) a content ratio of a lysophospholipid contained in a lipid forming the liposome with respect to a total amount of phospholipids other than the lysophospholipid contained in the lipid forming the liposome is 0.01 mol % to 5 mol % and (3) a nucleic acid analog anticancer agent/lipid ratio is 2 mass % to 10 mass %, and a method for producing the same.Type: ApplicationFiled: May 1, 2018Publication date: August 30, 2018Applicant: FUJIFILM CorporationInventors: Takahiro SEKIGUCHI, Mikinaga MORI, Kentaro NUMAJIRI, Hiroyuki KITAOKA
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Publication number: 20180243214Abstract: An object of the present invention is to provide a tumor therapeutic agent and a kit which have superior antitumor effects as compared with gemcitabine, a taxane antitumor agent, and a combination therapy thereof which have been put on the market. According to the present invention, there is provided a tumor therapeutic agent obtained by combining a taxane antitumor agent with a liposome composition in which gemcitabine or a salt thereof is contained in a liposome.Type: ApplicationFiled: May 1, 2018Publication date: August 30, 2018Applicant: FUJIFILM CorporationInventors: Tsukasa KITAHASHI, Shinji MIMA, Takeshi MATSUMOTO, Takahiro SEKIGUCHI, Mikinaga MORI
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Publication number: 20170202774Abstract: Provided are a liposome composition in which an osmotic pressure of an inner water phase is 2-fold to 8-fold relative to the osmotic pressure of an outer water phase, and which encapsulates a water-soluble drug in a dissolved state, and also exhibits excellent preservation stability; and a method for producing the same. According to the present invention, it is possible to provide a liposome composition, including liposomes obtained from lipids dissolved and emulsified in an organic solvent, each of which has an inner water phase and an aqueous solution which constitutes an outer water phase and in which the liposomes are dispersed, in which each of the liposomes encapsulates a water-soluble drug in a dissolved state, and an osmotic pressure of the inner water phase is 2-fold to 8-fold relative to the osmotic pressure of the outer water phase; and a method for producing the same.Type: ApplicationFiled: March 30, 2017Publication date: July 20, 2017Applicant: FUJIFILM CorporationInventors: Makoto ONO, Kohei ONO, Takeshi MATSUMOTO, Mikinaga MORI
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Publication number: 20170042813Abstract: Provided are a liposome composition in which an osmotic pressure of an inner water phase is 2-fold to 8-fold relative to the osmotic pressure of an outer water phase, and which encapsulates a water-soluble drug in a dissolved state, and also exhibits excellent preservation stability; and a method for producing the same. According to the present invention, it is possible to provide a liposome composition, including liposomes obtained from lipids dissolved and emulsified in an organic solvent, each of which has an inner water phase and an aqueous solution which constitutes an outer water phase and in which the liposomes are dispersed, in which each of the liposomes encapsulates a water-soluble drug in a dissolved state, and an osmotic pressure of the inner water phase is 2-fold to 8-fold relative to the osmotic pressure of the outer water phase; and a method for producing the same.Type: ApplicationFiled: October 27, 2016Publication date: February 16, 2017Applicant: FUJIFILM CorporationInventors: Makoto ONO, Kohei ONO, Takeshi MATSUMOTO, Mikinaga MORI
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Publication number: 20170042811Abstract: Provided are a liposome composition which has a practically required long-term preservation stability, and which has a release rate of a drug on the order of several tens of hours due to releasability of a drug being able to be suitably controlled by rendering an inner water phase hyper-osmotic; and a method for producing the same. According to the present invention, it is possible to provide a liposome composition, including liposomes each of which has an inner water phase and an aqueous solution which constitutes an outer water phase and in which the liposomes are dispersed, in which the content of cholesterols is 10 mol % to 35 mol % with respect to the total amount of lipid components in the liposome composition, and each of the liposomes encapsulates a drug in a dissolved state, and an osmotic pressure of the inner water phase is 2-fold to 8-fold relative to the osmotic pressure of the outer water phase.Type: ApplicationFiled: October 27, 2016Publication date: February 16, 2017Applicant: FUJIFILM CorporationInventors: Makoto ONO, Kohei ONO, Takeshi MATSUMOTO, Mikinaga MORI
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Patent number: 8802426Abstract: A device for assay can evenly develop solution, and performs highly accurate and sensitive measurement. A first device part (10) maintains a second insoluble carrier (12) and a third insoluble carrier (13) in such a manner that they overlap with each other at a detection portion (14) of a first insoluble carrier (11). These three carriers (11), (12) and (13) are housed not in contact with each other. A pressing unit (18) having a pressing surface (18a) that is parallel to the detection portion (14) is provided on an inner surface of the second device part (20) facing the detection portion (14). The pressing surface (18a) is displaced by being pressed toward the detection portion (14), and presses, from the upper side of the first insoluble carrier (11), the second insoluble carrier (12) and the third insoluble carrier (13) onto the first insoluble carrier (11). The first device part (10) and the second device part (20) are joined together.Type: GrantFiled: March 30, 2010Date of Patent: August 12, 2014Assignee: FUJIFILM CorporationInventors: Mikinaga Mori, Junichi Katada, Takayoshi Oyamada, Hideyuki Karaki, Masayasu Konishi, Hiroki Terada
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Patent number: 8765457Abstract: A device for assay can evenly develop solution, and performs highly accurate and sensitive measurement. A first device part (10) maintains a second insoluble carrier (12) and a third insoluble carrier (13) in such a manner that they overlap with each other at a detection portion (14) of a first insoluble carrier (11). These three carriers (11), (12) and (13) are housed not in contact with each other. A pressing unit (18) having a pressing surface (18a) that is parallel to the detection portion (14) is provided on an inner surface of the second device part (20) facing the detection portion (14). The pressing surface (18a) is displaced by being pressed toward the detection portion (14), and presses, from the upper side of the first insoluble carrier (11), the second insoluble carrier (12) and the third insoluble carrier (13) onto the first insoluble carrier (11). The first device part (10) and the second device part (20) are joined together.Type: GrantFiled: March 30, 2010Date of Patent: July 1, 2014Assignee: FUJIFILM CorporationInventors: Mikinaga Mori, Junichi Katada, Takayoshi Oyamada, Hideyuki Karaki, Masayasu Konishi, Hiroki Terada
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Publication number: 20140093868Abstract: A chromatographic kit is provided including a labeling substance holding area having a labeling substance modified with a first binding substance of a test substance, and a labeling substance capturing area having a second binding substance of the test substance or a binding substance of the first binding substance in this order from upstream to downstream of a development direction of a test sample including the test substance, and further including an area having a color developing reagent in order to detect a first amplification reagent of two types of amplification reagents used to amplify the signal of the labeling substance when detecting the labeling substance.Type: ApplicationFiled: December 6, 2013Publication date: April 3, 2014Applicant: FUJIFILM CorporationInventors: Atsuhiko WADA, Mikinaga MORI
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Patent number: 8663910Abstract: A plurality of kinds of liquids, which are of at least three kinds, containing (a) a test body solution containing at least one kind of an analyte, and (b) at least two kinds of liquids selected from the group consisting of a reagent solution, an amplifying solution, and a detecting solution, are fed to a detection site containing a specific binding substance with respect to the analyte. A qualitative analysis or a quantitative analysis of the analyte contained in the test body solution is thereby performed. Directions of liquid feeding of all of the plurality of the kinds of the liquids vary from one another, and the plurality of the kinds of the liquids are caused to intersect with one another at the detection site.Type: GrantFiled: September 18, 2009Date of Patent: March 4, 2014Assignee: FUJIFILM CorporationInventors: Mikinaga Mori, Junichi Katada, Hiroyuki Chiku, Takayoshi Oyamada
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Publication number: 20120058465Abstract: A device for assay can evenly develop solution, and performs highly accurate and sensitive measurement. A first device part (10) maintains a second insoluble carrier (12) and a third insoluble carrier (13) in such a manner that they overlap with each other at a detection portion (14) of a first insoluble carrier (11). These three carriers (11), (12) and (13) are housed not in contact with each other. A pressing unit (18) having a pressing surface (18a) that is parallel to the detection portion (14) is provided on an inner surface of the second device part (20) facing the detection portion (14). The pressing surface (18a) is displaced by being pressed toward the detection portion (14), and presses, from the upper side of the first insoluble carrier (11), the second insoluble carrier (12) and the third insoluble carrier (13) onto the first insoluble carrier (11). The first device part (10) and the second device part (20) are joined together.Type: ApplicationFiled: March 30, 2010Publication date: March 8, 2012Applicant: Fujifilm CorporationInventors: Mikinaga Mori, Junichi Katada, Takayoshi Oyamada, Hideyuki Karaki, Masayasu Konishi, Hiroki Terada
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Publication number: 20100075440Abstract: A plurality of kinds of liquids, which are of at least three kinds, containing (a) a test body solution containing at least one kind of an analyte, and (b) at least two kinds of liquids selected from the group consisting of a reagent solution, an amplifying solution, and a detecting solution, are fed to a detection site containing a specific binding substance with respect to the analyte. A qualitative analysis or a quantitative analysis of the analyte contained in the test body solution is thereby performed. Directions of liquid feeding of all of the plurality of the kinds of the liquids vary from one another, and the plurality of the kinds of the liquids are caused to intersect with one another at the detection site.Type: ApplicationFiled: September 18, 2009Publication date: March 25, 2010Inventors: Mikinaga MORI, Jinichi Katada, Hiroyuki Chiku, Takayoshi Oyamada
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Publication number: 20090246815Abstract: The present invention provides a protease detection material having, on a support, at least a layer containing a dye precursor and a layer which contains a protease substrate and is disposed on the same side of the support as the layer containing the dye precursor and farther from the support than the layer containing the dye precursor, wherein the layer containing the protease substrate further contains a development center-forming substance. Further, a set of protease detection materials and a method for measuring protease using the above-described protease detection material are provided. A protease detection material, a set of protease detection materials, and a method of measuring protease which allow protease activity to be measured promptly with high sensitivity, and that allow, at the same time, morphological observation of tissues and cells on a thin film to be performed easily.Type: ApplicationFiled: March 30, 2009Publication date: October 1, 2009Inventors: Sadanobu SHUTO, Katsuhisa OHZEKI, Mikinaga MORI
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Publication number: 20060116288Abstract: A thermal recording material is provided in which a thermal recording layer containing a color developer represented by the following formula (1) is provided on a substantially transparent polymer support, and a haze value is set to be 65% or less [In formula (1), R1 to R4 each independently hydrogen, an alkyl group, an alkenyl group, an aralkyl group, or a phenyl group; the total number of carbon atoms of R1 to R4 is 2 to 9; M is n-valent metal ion; and n is integer from 1 to 3.].Type: ApplicationFiled: November 30, 2005Publication date: June 1, 2006Inventors: Mikinaga Mori, Toshihide Aoshima
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Patent number: D686311Type: GrantFiled: November 9, 2011Date of Patent: July 16, 2013Assignee: FUJIFILM CorporationInventor: Mikinaga Mori