Patents by Inventor Mikio Hoshino

Mikio Hoshino has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Rare earth metal complex having phenanthroline compound as ligand
    Patent number: 9187690
    Abstract: The present invention provides a rare earth metal complex represented by the following formula (I).
    Type: Grant
    Filed: March 12, 2012
    Date of Patent: November 17, 2015
    Assignee: B.R.A.H.M.S. GmbH
    Inventors: Mikio Hoshino, Toshisada Yano, Yasukazu Yamanaka
  • RARE EARTH METAL COMPLEX HAVING PHENANTHROLINE COMPOUND AS LIGAND
    Publication number: 20140058073
    Abstract: The present invention provides a rare earth metal complex represented by the following formula (I).
    Type: Application
    Filed: March 12, 2012
    Publication date: February 27, 2014
    Applicant: B.R.A.H.M.S. GmbH
    Inventors: Mikio Hoshino, Toshisada Yano, Yasukazu Yamanaka
  • Compounds having phenanthroline structure
    Patent number: 8648194
    Abstract: The present invention provides a novel compound having a phenanthroline structure represented by formula (I) or a salt thereof:
    Type: Grant
    Filed: September 13, 2010
    Date of Patent: February 11, 2014
    Assignee: B.R.A.H.M.S GmbH
    Inventors: Mikio Hoshino, Toshisada Yano
  • NOVEL COMPOUNDS HAVING PHENANTHROLINE STRUCTURE
    Publication number: 20120238748
    Abstract: The present invention provides a novel compound having a phenanthroline structure represented by formula (I) or a salt thereof:
    Type: Application
    Filed: September 13, 2010
    Publication date: September 20, 2012
    Applicant: B.R.A.H.M.S GmbH
    Inventors: Mikio Hoshino, Toshisada Yano
  • Method for inducing differentiation to skeletal muscle cells
    Patent number: 7718429
    Abstract: A method of efficiently and conveniently inducing differentiation from bone marrow stromal cells to skeletal muscle cells, which comprises the steps of: (a) the step of adding one or more kinds of substances selected from the group consisting of a cyclic AMP increasing agent, a cAMP analogue, and a cell differentiation stimulating factor to a culture of bone marrow stromal cells, wherein said bone marrow stromal cells are not treated with a demethylating agent, and culturing the cells; (b) the step of introducing a Notch gene and/or a Notch signaling related gene into the cells obtained in the step (a), and culturing the cells to obtain a culture of myoblasts, provided that said culture does not contain the cells introduced with the gene and non-introduced cells; and (c) the step of adding a Notch ligand to the culture of myoblasts obtained in the step (b), and culturing the cells.
    Type: Grant
    Filed: December 22, 2005
    Date of Patent: May 18, 2010
    Assignee: Kyoto University
    Inventors: Mari Dezawa, Yo-ichi Nabeshima, Mikio Hoshino
  • Method for Inducing Differentiation to Skeletal Muscle Cells
    Publication number: 20080113435
    Abstract: A method of efficiently and conveniently inducing differentiation from bone marrow stromal cells to skeletal muscle cells, which comprises the steps of: (a) the step of adding one or more kinds of substances selected from the group consisting of a cyclic AMP increasing agent, a cAMP analogue, and a cell differentiation stimulating factor to a culture of bone marrow stromal cells, wherein said bone marrow stromal cells are not treated with a demethylating agent, and culturing the cells; (b) the step of introducing a Notch gene and/or a Notch signaling related gene into the cells obtained in the step (a), and culturing the cells to obtain a culture of myoblasts, provided that said culture does not contain the cells introduced with the gene and non-introduced cells; and (c) the step of adding a Notch ligand to the culture of myoblasts obtained in the step (b), and culturing the cells.
    Type: Application
    Filed: December 22, 2005
    Publication date: May 15, 2008
    Applicant: KYOTO UNIVERSITY
    Inventors: Mari Dezawa, Yo-ichi Nabeshima, Mikio Hoshino