Patents by Inventor Mikio Kondo

Mikio Kondo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240124571
    Abstract: Provided is a substance capable of effectively suppressing cancer metastasis or a pharmaceutical composition that effectively acts on an inflammatory disease. The pharmaceutical composition is a pharmaceutical composition containing, as an active ingredient, an antibody or an antibody fragment thereof having antigen-binding activity for an S100A8/A9 heterodimer, and blocks interaction between S100A8/A9 and a group of receptors therefor, to thereby strongly suppress cancer metastasis both in vitro and in vivo, or alleviate inflammation. That is, the anti-S100A8/A9 antibody or the antibody fragment thereof can strongly suppress cancer metastasis or alleviate inflammation, by virtue of its blocking action on the interaction between S100A8/A9 and the group of receptors therefor.
    Type: Application
    Filed: November 17, 2023
    Publication date: April 18, 2024
    Applicant: National University Corporation Okayama University
    Inventors: Masakiyo SAKAGUCHI, Shinichi TOYOOKA, Shuta TOMIDA, Kazuhiko SHIEN, Hiroki SATO, Rie KINOSHITA, Junichiro FUTAMI, Kota ARAKI, Mikio OKAZAKI, Eisaku KONDO, Yusuke INOUE, Akira YAMAUCHI
  • Patent number: 8324528
    Abstract: The present invention provides a manufacturing method for accurate, fine and efficient processing of a work piece to be processed and prevention of graphitization of the work piece to be processed, when sintered diamond is processed by a laser beam. The method provides process comprising steps of (a) irradiating outer circumference of a scribing wheel 2 with a laser beam from the side of the wheel, (b) moving the laser beam relative to the wheel 2, (c) forming continuously along the circumferential direction in the required space fine grooves with openings directed radially on a ridge site, (d) irradiating the laser beam onto the site to be processed at a speed of the laser beam relative to the work piece, and (e) forming the work piece into a minute shape within a depth of less than 200 ?m.
    Type: Grant
    Filed: February 2, 2006
    Date of Patent: December 4, 2012
    Assignee: Mitsuboshi Diamond Industrial Co., Ltd
    Inventors: Mikio Kondo, Kazuhisa Kuriyama, Hiroshi Tomimori
  • Publication number: 20090039061
    Abstract: The present invention provides a manufacturing method for accurate, fine and efficient processing of a work piece to be processed and prevention of graphitization of the work piece to be processed, when sintered diamond is processed by a laser beam. The method provides process comprising steps of (a) irradiating outer circumference of a scribing wheel 2 with a laser beam from the side of the wheel, (b) moving the laser beam relative to the wheel 2, (c) forming continuously along the circumferential direction in the required space fine grooves with openings directed radially on a ridge site, (d) irradiating the laser beam onto the site to be processed at a speed of the laser beam relative to the work piece, and (e) forming the work piece into a minute shape within a depth of less than 200 ?m.
    Type: Application
    Filed: February 2, 2006
    Publication date: February 12, 2009
    Applicant: MITSUBOSHI DIAMOND INDUSTRIAL., LTD.
    Inventors: Mikio Kondo, Kazuhisa Kuriyama, Hiroshi Tomimori
  • Patent number: 7459032
    Abstract: A pressurizing forming process includes the steps of applying a higher fatty acid-based lubricant on a surface of a metallic workpiece and/or a forming surface of a forming tool, and forming, wherein a lubricating film including metallic soap is formed on a pressurized-and-contacted interface, at which the surface of the metallic workpiece and the surface of the forming tool are pressed against and are brought into contact with each other, in forming the metallic workpiece by pressurizing with the forming tool. The metallic workpiece and/or the forming tool can be heated prior to or in the forming step.
    Type: Grant
    Filed: June 12, 2002
    Date of Patent: December 2, 2008
    Assignees: Kabushiki Kaisha Toyota Chuo Kenkyusho, Toyota Jidosha Kabushiki Kaisha, Tokyo Sintered Metals Corporation
    Inventors: Mikio Kondo, Akira Sekiguchi, Naoki Miyagawa, Shigehide Takemoto, Hiroshi Okajima
  • Patent number: 7175404
    Abstract: The present invention is an apparatus for filling a multi-powder including a powder box (10) including a plurality of powder chambers storing a plurality of powders whose constituent compositions differ in a divided manner, and a gas feed pipe (14) disposed on the bottom side of the powder chamber and having an introducing hole for introducing a gas, wherein it can fill a plurality of the powders into a cavity (24) at once through the bottom openings of the powder box by introducing a gas through the introducing hole to substantially equalize the respective flow resistances of a plurality of the powders. Thus, it is possible to fill the powders whose constituent compositions differ at once without disposing them in a mixed manner.
    Type: Grant
    Filed: March 27, 2002
    Date of Patent: February 13, 2007
    Assignees: Kabushiki Kaisha Toyota Chuo Kenkyusho, Toyota Jidosha Kabushiki Kaisha
    Inventors: Mikio Kondo, Hiroshi Okajima, Yoshitaka Takahashi
  • Patent number: 7083760
    Abstract: This invention provides a method of forming a powder compact which can produce a high density compact under a high pressure and at the same time can reduce pressure for ejecting the compact from a die. This method comprises the application step of applying a higher fatty acid lubricant to an inner surface of a heated die, and the compaction step of filling metal powder into the die and compacting the metal powder under such a pressure as to force the higher fatty acid lubricant to be chemically bonded with the metal powder and form a metallic soap coating. Since the metallic soap coating is formed between the die and a compact, friction force between the die and the compact is decreased and ejecting pressure can be remarkably decreased despite of compaction with high pressure. Besides, a high density compact can be obtained owing to the compaction with high pressure.
    Type: Grant
    Filed: August 13, 2001
    Date of Patent: August 1, 2006
    Assignees: Kabushiki Kaisha Toyota Chuo Kenkyusho, Toyota Jidosha Kabushiki Kaisha
    Inventors: Mikio Kondo, Yoji Awano, Masatoshi Sawamura, Hiroshi Okajima, Shigehide Takemoto
  • Patent number: 6903641
    Abstract: The present invention is characterized in that, in a powder magnetic core obtained by compaction of an iron-based magnetic powder covered with an insulation film, a saturation magnetization Ms is Ms?1.9 T in a 1.6 MA/m magnetic field; a specific resistance ? is ??1.5 ??m; a magnetic flux density B2k is B2k?1.1 T in a 2 kA/m magnetic field; and a magnetic flux density B10k is B10k?1.6 T in a 10 kA/m magnetic field. In accordance with the present invention, it has been possible to industrially carry out compacting iron-based magnetic powders under remarkably high compacting pressures. As a result, high-performance powder magnetic cores are obtained which have a high density, and which are good in terms of the specific resistance and magnetic permeability.
    Type: Grant
    Filed: January 17, 2002
    Date of Patent: June 7, 2005
    Assignees: Kabushiki Kaisha Toyota Chuo Kenkyusho, Toyota Jidosha Kabushiki Kaisha
    Inventors: Mikio Kondo, Shin Tajima, Takeshi Hattori, Yoji Awano, Hiroshi Okajima
  • Publication number: 20040141871
    Abstract: The present invention is an apparatus for filling a multi-powder including a powder box (10) including a plurality of powder chambers storing a plurality of powders whose constituent compositions differ in a divided manner, and a gas feed pipe (14) disposed on the bottom side of the powder chamber and having an introducing hole for introducing a gas, wherein it can fill a plurality of the powders into a cavity (24) at once through the bottom openings of the powder box by introducing a gas through the introducing hole to substantially equalize the respective flow resistances of a plurality of the powders. Thus, it is possible to fill the powders whose constituent compositions differ at once without disposing them in a mixed manner.
    Type: Application
    Filed: October 27, 2003
    Publication date: July 22, 2004
    Inventors: Mikio Kondo, Hiroshi Okajima, Yoshitaka Takahashi
  • Publication number: 20040061582
    Abstract: The present invention is characterized in that, in a powder magnetic core obtained by compaction of an iron-based magnetic powder covered with an insulation film, a saturation magnetization Ms is Ms≧1.9 T in a 1.6 MA/m magnetic field; a specific resistance &rgr; is &rgr;≧1.5 &mgr;&OHgr;m; a magnetic flux density B2k is B2k≧1.1 T in a 2 kA/m magnetic field; and a magnetic flux density B10k is B10k≧1.6 T in a 10 kA/m magnetic field. In accordance with the present invention, it has been possible to industrially carry out compacting iron-based magnetic powders under remarkably high compacting pressures. As a result, high-performance powder magnetic cores are obtained which have a high density, and which are good in terms of the specific resistance and magnetic permeability.
    Type: Application
    Filed: July 18, 2003
    Publication date: April 1, 2004
    Inventors: Mikio Kondo, Shin Tajima, Takeshi Hattori, Yoji Awano, Hiroshi Okajima
  • Publication number: 20030003009
    Abstract: A pressurizing forming process includes the steps of applying a higher fatty acid-based lubricant on a surface of a metallic workpiece and/or a forming surface of a forming tool, and forming, wherein a lubricating film including metallic soap is formed on a pressurized-and-contacted interface, at which the surface of the metallic workpiece and the surface of the forming tool are pressed against and are brought into contact with each other, in forming the metallic workpiece by pressurizing with the forming tool. The metallic workpiece and/or the forming tool can be heated prior to or in the forming step.
    Type: Application
    Filed: June 12, 2002
    Publication date: January 2, 2003
    Applicant: KABUSHIKI KAISHA TOYOTA CHUO KENKYUSHO
    Inventors: Mikio Kondo, Akira Sekiguchi, Naoki Miyagawa, Shigehide Takemoto, Hiroshi Okajima
  • Publication number: 20020034453
    Abstract: This invention provides a method of forming a powder compact which can produce a high density compact under a high pressure and at the same time can reduce pressure for ejecting the compact from a die.
    Type: Application
    Filed: August 13, 2001
    Publication date: March 21, 2002
    Applicant: KABUSHIKI KAISHA TOYOTA CHUO KENKYUSHO
    Inventors: Mikio Kondo, Yoji Awano, Masatoshi Sawamura, Hiroshi Okajima, Shigehide Takemoto
  • Patent number: 4948487
    Abstract: An apparatus for effecting, on a metallic member, an electrolytic process such as descaling, electrolytic acid cleaning, passivation, electrolytic polishing, coloring or plating. The apparatus comprises a rotatable cylindrical electrode arranged to oppose the member to be processed, with a gap between them, a paste electrolyte supply device for introducing a paste electrolyte into the gap between the cylindrical electrode and the metallic member, a pad disposed on the outer peripheral surface of the cylindrical electrode and capable of retaining by impregnation the paste electrolyte supplied by the paste electrolyte supply device; an electrical power supply device for causing an electric current to flow between the cylindrical electrode and the member across the paste electrolyte; and a moving device for effecting relative movement between said metallic member and said cylindrical electrode.
    Type: Grant
    Filed: November 27, 1989
    Date of Patent: August 14, 1990
    Assignee: Kawasaki Steel Corp.
    Inventors: Tsukasa Imazu, Mitsuo Kimura, Yoshiyuki Saito, Nobuyoshi Ishiwatari, Yoshio Miyano, Mikio Kondo
  • Patent number: 4795908
    Abstract: An infrared detector is arranged so that a detection-input processing circuit part including an infrared sensor mounted on a circuit board is housed as isolated from ambient air in a chamber inhibiting any ambient air inflow, for sensing infrared rays emitted from a human body or the like object as condensed by a condenser irrespective of the ambient air conditions, the sensing ability of the infrared sensor the accuracy of which is likely to be easily deteriorated even with a very small change in the ambient temperature can be thereby stabilized, and a highly accurate infrared detection can be constantly achieved.
    Type: Grant
    Filed: October 30, 1986
    Date of Patent: January 3, 1989
    Assignee: Masushita Electric Works, Ltd.
    Inventors: Makoto Morimoto, Mikio Kondo
  • Patent number: 4672206
    Abstract: A passive infrared detector including an optical collector releasably attached to a base with a sensor on which incident infrared radiation directed through the optical collector is focused. The sensor is held by a joint member which is pivotally supported on the base and to which said optical collector is releasably attached, whereby the optical collector is rotatable together with the joint member relative to the base for adjustment of its angular position and the optical collector can be alone replaced as necessary without having to replace the base, the sensor and its associated electric circuitry.
    Type: Grant
    Filed: July 25, 1985
    Date of Patent: June 9, 1987
    Assignee: Matsushita Electric Works, Ltd.
    Inventors: Muneo Suzuki, Mikio Kondo, Makoto Morimoto, Kazuhito Kayanoki
  • Patent number: 4551711
    Abstract: An infrared-type intrusion detector for monitoring the presence of a person is disclosed. The detector has a plurality of concave reflector segments for defining separate fields of view. Infrared radiation emanating from the person in any of the fields of view is collected and focused upon a single sensing element to produce a cautionary signal representative of such detection. Plane mirrors are introduced in an optical reflection system of the detector to reflect the radiation from the reflector segments upon the sensing element, such as to reduce the spacing or dimension required for the optical system along the optical axis of the sensing element, whereby the detector is allowed to be made compact in size.
    Type: Grant
    Filed: January 30, 1984
    Date of Patent: November 5, 1985
    Assignee: Matsushita Electric Works, Ltd.
    Inventors: Shoichi Akiyama, Mikio Kondo
  • Patent number: 4466825
    Abstract: A process for operating blast furnaces is disclosed, which comprises assuming a plurality of reference spaces, each of which serves as a stacking space for burden material and is defined by a plurality of line segments having inclination angles .theta..sub.1 and .theta..sub.2 with respect to a horizontal line on a surface of a previously stacked burden, before a predetermined volume of the burden material is charged from a charging equipment; settling a newly stacked surface of the burden in one of the standard spaces in such a manner that the newly stacked surface consists of two line segments having inclination angle .theta..sub.1 and .theta..sub.
    Type: Grant
    Filed: July 29, 1983
    Date of Patent: August 21, 1984
    Assignee: Kawasaki Steel Corporaton
    Inventors: Mikio Kondo, Kyoji Okabe
  • Patent number: 4403142
    Abstract: A moving object detecting apparatus of which a plurality of light receiving means arranged to have a common light receiving zone and a plurality of independent light receiving zones are disposed within a single casing together with a light emitting means. Receiving order in the respective light receiving means of reflected light from a moving object within the zones is detected to discriminate moving direction of the object and desired indications are performed responsive to the discriminated direction.
    Type: Grant
    Filed: May 14, 1981
    Date of Patent: September 6, 1983
    Assignee: Matsushita Electric Works, Ltd.
    Inventor: Mikio Kondo
  • Patent number: 4400206
    Abstract: A process for estimating a particle size segregation in a burden layer at a blast furnace top is disclosed, which comprises measuring a particle size distribution of a burden material before the charging and a layer thickness distribution of the burden layer after the charging, and estimating a particle size distribution at every position in the burden layer charged at the furnace top on the basis of the above measured values, charging conditions and furnace operating conditions according to a simulation model of particle size segregation.
    Type: Grant
    Filed: May 28, 1981
    Date of Patent: August 23, 1983
    Assignee: Kawasaki Steel Corporation
    Inventor: Mikio Kondo
  • Patent number: 4292679
    Abstract: Means for mounting a member functioning with a directivity to a mounting station of an associated device or the like. A housing for the member with its functional end surface exposed to the exterior is tapered at the periphery toward the other end to be, for example, hemispherical and rotatably born at diametrally opposed positions adjacent the functional end surface by both ends of a semiarcuate bearing means, the mounting station has a hole including peripherally opposing grooves of a size and shape capable of slidably engaging with the tapered periphery of the housing and receiving semiarcuate body of the bearing means, the housing is inserted in the hole on said the other end side, and the semiarcuate body of the bearing means in the inserted position of the member engages slidably with a resilient means acting to resiliently urge the tapered periphery of the housing against peripheral edge of the hole.
    Type: Grant
    Filed: January 7, 1980
    Date of Patent: September 29, 1981
    Assignee: Matsushita Electric Works, Ltd.
    Inventors: Mikio Kondo, Hiromitsu Inoue, Hiroshi Ohashi
  • Patent number: 4287579
    Abstract: A moving object detecting device employing a pair of Doppler signals as a pair of vector signals of respective received-wave signals representing momentary reflected waves from a moving object. These vector signals are processed to obtain signals denoting in which ones of predetermined zones for the vector rotation depending on the movements of the object the vector is momentarily present, and shifting states of such zone signals through the zones are traced to sequentially determine the direction and period of the vector rotation and to actuate an alarm or the like when the rotation is in a fixed direction.
    Type: Grant
    Filed: November 8, 1979
    Date of Patent: September 1, 1981
    Assignee: Matsushita Electric Works, Ltd.
    Inventors: Hiromitsu Inoue, Hiroshi Ohashi, Mikio Kondo