Patents by Inventor Mikio Okamura

Mikio Okamura has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of treating hypertension
    Patent number: 7820667
    Abstract: It is an object of the present invention to provide a therapeutic agent for effectively preventing or ameliorating diseases caused by dysfunction of NOS. The present invention provides a pharmaceutical composition for preventing and/or treating diseases associated with dysfunction of NOS, comprising as an effective ingredient, a compound of the formula (I): wherein R1 and R2 each represents a hydrogen atom or, taken together with each other, represent a single bond, while R3 represents —CH(OH)CH(OH)CH3, —CH(OCOCH3)CH(OCOCH3)CH3, —CH3, —CH2OH, or a phenyl group when R1 and R2 each represents a hydrogen atom, or —COCH(OH)CH3 when R1 and R2 together represent a single bond, or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: August 24, 2005
    Date of Patent: October 26, 2010
    Assignee: Daiichi Sankyo Company, Limited
    Inventors: Takafumi Ishihara, Yoshiharu Kanayama, Mikio Okamura, Junichi Yoshikawa, Haruo Shintaku
  • Prophylactic or therapeutic agents for diseases associated with dysfunction of NOS
    Publication number: 20060009458
    Abstract: It is an object of the present invention to provide a therapeutic agent for effectively preventing or ameliorating diseases caused by dysfunction of NOS. The present invention provides a pharmaceutical composition for preventing and/or treating diseases associated with dysfunction of NOS, comprising as an effective ingredient, a compound of the formula (I): wherein R1 and R2 each represents a hydrogen atom or, taken together with each other, represent a single bond, while R3 represents —CH(OH)CH(OH)CH3, —CH(OCOCH3)CH(OCOCH3)CH3, —CH3, —CH2OH, or a phenyl group when R1 and R2 each represents a hydrogen atom, or —COCH(OH)CH3 when R1 and R2 together represent a single bond, or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: August 24, 2005
    Publication date: January 12, 2006
    Inventors: Takafumi Ishihara, Yoshiharu Kanayama, Mikio Okamura, Junichi Yoshikawa, Haruo Shintaku
  • Prophylactic or therapeutic agents for diseases associated with dysfunction of NOS
    Publication number: 20030232835
    Abstract: It is an object of the present invention to provide a therapeutic agent for effectively preventing or ameliorating diseases caused by dysfunction of NOS.
    Type: Application
    Filed: April 8, 2003
    Publication date: December 18, 2003
    Inventors: Takafumi Ishihara, Yoshiharu Kanayama, Mikio Okamura, Junichi Yoshikawa, Haruo Shintaku
  • Prophylactic or therapeutic agents for drug-induced renal injury
    Patent number: 6288067
    Abstract: It is an object of the present invention to provide a pharmaceutical composition for effectively preventing or improving drug-induced renal injury. The present invention provides pharmaceutical composition for preventing or treating drug-induced renal injury, comprising as an active ingredient a compound of the formula (I): wherein R1 and R2 each represents a hydrogen atom or taken together with each other represent a single bond, while R3 represents —CH(OH)CH(OH)CH3, —CH(OCOCH3)CH(OCOCH3)CH3, —CH3, —CH2OH or a phenyl group when R1 and R2 each represents a hydrogen atom, or —COCH(OH)CH3 when R1 and R2 together represent a single bond, or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: October 27, 1999
    Date of Patent: September 11, 2001
    Assignee: Suntory Limited
    Inventors: Mikio Okamura, Yoshiharu Kanayama, Junichi Yoshikawa, Haruo Shintaku