Patents by Inventor Mikio Shoji

Mikio Shoji has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8937218
    Abstract: A transformed soybean plant having a gene encoding a modified seed storage protein introduced therein, obtained by inserting a gene encoding an Alzheimer's disease vaccine to a variable region(s) of a gene encoding a wild-type seed storage protein, is produced, and said vaccine is produced and accumulated in the seeds thereof.
    Type: Grant
    Filed: November 26, 2009
    Date of Patent: January 20, 2015
    Assignee: Hokko Chemical Industry Co., Ltd.
    Inventors: Teruhiko Terakawa, Hisakazu Hasegawa, Masao Ishimoto, Mikio Shoji, Takeshi Kawarabayashi, Yasuko Utsumi
  • Patent number: 8912145
    Abstract: A vaccine composition for prophylaxis and/or therapy of Alzheimer's disease, which comprises a fusion protein prepared by inserting a single or tandemly repeated multiple copies of amyloid ? antigenic peptide having 5 to 15 continuous amino acid residues derived from the N-terminus of amyloid ? peptide into a wild type seed storage protein.
    Type: Grant
    Filed: November 7, 2011
    Date of Patent: December 16, 2014
    Assignee: Hokko Chemical Industry Co., Ltd.
    Inventors: Teruhiko Terakawa, Hisakazu Hasegawa, Yasushi Shimada, Atsushi Takahashi, Takeshi Kawarabayashi, Mikio Shoji
  • Publication number: 20120052086
    Abstract: A vaccine composition for prophylaxis and/or therapy of Alzheimer's disease, which comprises a fusion protein prepared by inserting a single or tandemly repeated multiple copies of amyloid ? antigenic peptide having 5 to 15 continuous amino acid residues derived from the N-terminus of amyloid ? peptide into a wild type seed storage protein.
    Type: Application
    Filed: November 7, 2011
    Publication date: March 1, 2012
    Applicant: Hokko Chemical Industry Co., Ltd.
    Inventors: Teruhiko Terakawa, Hisakazu Hasegawa, Yasushi Shimada, Atsushi Takahashi, Takeshi Kawarabayashi, Mikio Shoji
  • Publication number: 20110243975
    Abstract: A transformed soybean plant having a gene encoding a modified seed storage protein introduced therein, obtained by inserting a gene encoding an Alzheimer's disease vaccine to a variable region(s) of a gene encoding a wild-type seed storage protein, is produced, and said vaccine is produced and accumulated in the seeds thereof.
    Type: Application
    Filed: November 26, 2009
    Publication date: October 6, 2011
    Inventors: Teruhiko Terakawa, Hisakazu Hasegawa, Masao Ishimoto, Shigeru Utsumi, Yasuko Utsumi, Mikio Shoji, Takeshi Kawarabayashi
  • Publication number: 20070031416
    Abstract: The present invention intended to provide an agent for preventing/treating Alzheimer's disease. More specifically, the present invention provides an agent for preventing/treating Alzheimer's disease, etc., which comprises a monoclonal antibody specifically reacting with a partial peptide at the C-terminal region of a ?-amyloid or its derivatives.
    Type: Application
    Filed: September 8, 2004
    Publication date: February 8, 2007
    Inventors: Mikio Shoji, Asano Asami, Nobuhiro Suzuki
  • Patent number: 6491586
    Abstract: In a stator shaft in which a shaft member is press-fitted into a press-fit bore of a flange member, first flow passages are formed in the shaft member, and blind bores extending linearly at right angles to a shaft axis from outer circumferential surfaces of the flange member and through the press-fit bore, and communication bores 103 extending linearly from a side surface of the flange member and communicating with free end portions of the blind bores are further formed. Oil passages formed of the parts of the blind bores which extend from the press-fit bore to the free end portions thereof, and communication bores constitute second flow passages, and the shaft member is press-fitted into the press-fit bore with the shaft member positioned so that the portions of the second flow passages which are opened in the press-fit bore, and first flow passages communicate with each other in a mutually opposed state, whereby the first and second flow passages are communicated with each other.
    Type: Grant
    Filed: December 7, 2000
    Date of Patent: December 10, 2002
    Assignee: Honda Giken Kogyo Kabushiki Kaisha
    Inventors: Takashi Nakamura, Mikio Shoji, Katsuyuki Narai
  • Publication number: 20020026997
    Abstract: The invention provides a heat recovery type heat storage apparatus which makes an apparatus small-sized and compact and has a high reliability and an improved efficiency. In a heat recovery type heat storage apparatus transferring an exhaust heat contained in an exhaust gas supplied from a heat discharge apparatus so as to accumulate heat, there are provided a heat exchanger provided within an exhaust duct for discharging the exhaust gas, a compression gas source connected to the heat exchanger via an inlet pipe, and an injection portion provided at an end portion of an outlet pipe of the heat exchanger and inserted within a liquid received within a tank, and a gas is introduced to the heat exchanger from the compression gas source so as to be blown within the liquid from the injection portion.
    Type: Application
    Filed: August 31, 2001
    Publication date: March 7, 2002
    Inventors: Michio Yanadori, Katsuyoshi Terakado, Mikio Shoji
  • Patent number: 6037521
    Abstract: The invention relates to an animal model of human Alzheimer's disease that is useful for determining the mechanism of the disease and for developing and testing potential therapeutic drugs. More particularly, the present invention relates to the creation of transgenic non-human mammalian animals having integrated into their genome an exogenous DNA construct that encodes a portion of a .beta.-amyloid precursor protein ("APP") and that is designed to overexpress in various types of animal tissues.
    Type: Grant
    Filed: November 14, 1994
    Date of Patent: March 14, 2000
    Assignee: Hoechst Japan Limited
    Inventors: Masahiro Sato, Takashi Kobayashi, Norihiro Tada, Mikio Shoji, Takeshi Kawarabayashi
  • Patent number: 4738084
    Abstract: A power grass mower (1; 100; 200) comprising a grass cutter (6) disposed under a mower body (2), a cutter housing (7; 107), a travelling mechanism (3, 4; 203, 204, 201) adapted to have the mower (1; 100; 200) travel, a power source (5) mounted on the mower body (2) to drive the cutter (6) and the travelling mechanism (3, 4; 203, 204, 201), and a handle member (14) connected to the mower body (2). The power grass mower (1; 100; 200) further comprises a handle position setting mechanism (39) for interconnecting a lower end part (14c) of the handle member (14) with the mower body (2), such that the handle member (14) is selectively turningly movable in the plan view thereof, relative to the mower body (2), substantially about the lower end part (14c) thereof, and for locking to set the handle member (14) at a voluntarily selected turning position thereof.
    Type: Grant
    Filed: September 13, 1985
    Date of Patent: April 19, 1988
    Assignee: Honda Giken Kogyo Kabushiki Kaisha
    Inventors: Takeo Ogano, Mikio Shoji, Toshihiro Toda
  • Patent number: 4716717
    Abstract: There is disclosed a power lawn mower which comprises a carriage having a top deck and side walls, a pair of front wheels, a pair of rear wheels having corresponding wheel axle shafts, a cutting mechanism having a rotary cutting element, a prime mover mounted on the top deck of the carriage and having an output shaft drivingly connected to the cutting element to rotate the same, and a rear wheel drive mechanism for transmitting driving power of the prime mover to the rear wheels and including at least one drive shaft. In this arrangement, the carriage includes front and rear openings. The front wheels are independently supported on the front portion of the carriage and the rear wheels are independently supported on the rear portion of the carriage. Further, front and rear guard members are swingably mounted to the lower surface of front and rear portions of the top deck, respectively.
    Type: Grant
    Filed: February 10, 1986
    Date of Patent: January 5, 1988
    Assignee: Honda Giken Kogyo Kabushiki Kaisha
    Inventors: Takeo Ogano, Yoshihiro Toda, Masato Mukainakano, Mikio Shoji