Abstract: The present invention aims at limiting the pressure loss and smoothly discharging water treated by ion exchangers to the outside of the apparatus. Ion exchanging apparatus 1 has outer vessel 3 that has inner space 2; and ion exchanger support 4 that separates at least a part of inner space 2 into upper space 2a and lower space 2b and that can support ion exchangers to be loaded in upper space 2a. At least a part of an upper surface of the ion exchanger support is made from at least one screen which supports the ion exchangers and which has a flow path allowing water treated by the ion exchangers to flow into the lower space 2b.

Abstract: The present invention aims at limiting the pressure loss and smoothly discharging water treated by ion exchangers to the outside of the apparatus. Ion exchanging apparatus 1 has outer vessel 3 that has inner space 2; and ion exchanger support 4 that separates at least a part of inner space 2 into upper space 2a and lower space 2b and that can support ion exchangers to be loaded in upper space 2a. At least a part of an upper surface of the ion exchanger support is made from at least one screen which supports the ion exchangers and which has a flow path allowing water treated by the ion exchangers to flow into the lower space 2b.

Abstract: A filtration and demineralization apparatus 10 including a vessel 20 in a form of a body of revolution; a hollow columnar body 40 that is located in an internal space of the vessel 20, one end 40a of the columnar body being connected to an inner surface of the vessel 20 along an entire circumference of the end, and the other end 40b of the columnar body forming an opening; and a partition plate 44 that is connected to the other end 40b of the hollow columnar body along an entire circumference of the other end 40b, the partition plate being configured to separate an inside space or an outside space of the hollow columnar body 40 as an independent space in the vessel. The partition plate 44 has a circulation port 43 that allows water that is to be treated to pass therethrough.

Abstract: A filtration and demineralization apparatus that is capable of reducing the cost of the apparatus and building cost by using an apparatus whose height is limited, and that is also capable of ensuring sufficient treatment capacity, as well as good operability, is provided. A filtration and demineralization apparatus 10 comprises a vessel 20 in a form of a body of revolution; a hollow columnar body 40 that is located in an internal space of the vessel 20, one end 40a of the columnar body being connected to an inner surface of the vessel 20 along an entire circumference of the end, and the other end 40b of the columnar body forming an opening; and a partition plate 44 that is connected to the other end 40b of the hollow columnar body along an entire circumference of the other end 40b, the partition plate being configured to separate an inside space or an outside space of the hollow columnar body 40 as an independent space in the vessel.

Abstract: An oxidative stress inhibitor comprising a spherical activated carbon as an effective component is disclosed. The present invention is effective in the prevention or the treatment of a disease caused by oxidative stress, such as a kidney disease, a circulatory disease (for example, cardiovascular disease), a cancer, a diabetes, a cerebral stroke, or an arterial sclerosis.

Abstract: An agent for removing a circulatory dysfunction factor, which is effective for ameliorating a circulatory dysfunction, particularly a heart failure, and for treating or preventing circulatory diseases, for example, heart diseases, such as a cardiac failure or a congestive cardiac failure, or a phlebemphraxis is provided. The agent for removing the circulatory dysfunction factor contains a spherical activated carbon as an effective ingredient.

Abstract: A novel benzimidazole derivative [specifically, for example, 2-ethoxy-1-[{4′-(2″-N,N-dimethylaminoethoxycarbonyl)phenyl}methyl]-1H-benzimidazole-6-carboxylic acid morpholide] represented by formula (I) and a salt thereof. The compound exhibits satisfactory curative effects for cardiac and nephric diseases, although having little action on blood-pressure.

Abstract: This invention relates to cardiac diseases improving agents substantially free from antagonistic action to type 1 receptor of angiotensin II which participates to hypotensive action. Particularly, this invention relates to cardiac diseases improving agents composed of effective ingredients of aromatic compounds or pharmacologically acceptable salts thereof shown by below mentioned general formula. Chemical formula 1 [General formula (I)]  (wherein, substituents thereof typically include, R1, R4, R13 representing hydrogen atom, an alkyl group, a haloalkyl group and so forth, R8 representing —CO—, —SO2— or single bond, R2 representing a 3-7 membered aliphatic cyclic amino group having at least one nitrogen atom, R7 representing —CO—or —SO2—, and R12 representing N-substituted valeramido group.

Abstract: This invention relates to cardiac diseases improving agents substantially free from antagonistic action to type 1 receptor of angiotensin II which participates to hypotensive action. Particularly, this invention relates to cardiac diseases improving agents composed of effective ingredients of aromatic compounds or pharmacologically acceptable salts thereof shown by below mentioned general formula. ##STR1## (wherein, substituents thereof typically include, R.sup.1, R.sup.4, R.sup.13 representing hydrogen atom, an alkyl group, a haloalkyl group and so forth, R.sup.8 representing --CO--, --SO.sub.2 -- or single bond, R.sup.2 representing a 3-7 membered aliphatic cyclic amino group having at least one nitrogen atom, R.sup.7 representing --CO-- or --SO.sub.2 --, and R.sup.12 representing N-substituted valeramido group.