Patents by Inventor Mikkel Gacek

Mikkel Gacek has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 4478839
    Abstract: Compounds of general formula: ##STR1## (wherein X represents a halogen atom or a trifluoromethyl group; R.sup.1 and R.sup.2, which may be the same or different, each represents a hydrogen atom, or a C.sub.1-4 alkyl group, and R.sup.3 represents a hydrogen atom or a C.sub.1-5 saturated or unsaturated, straight or branched acyclic aliphatic group; a C.sub.3-8 saturated or unsaturated cyclic aliphatic group; a heterocyclic substituted aliphatic group; an araliphatic group; or a heterocyclic or carbocyclic aryl group; any of said groups optionally carrying one or more substituents selected from halogen, oxo, hydroxy, mercapto, C.sub.1-4 alkyl, C.sub.1-4 alkoxy, C.sub.1-4 alkanoyloxy and amino) and, where an acidic or basic group is present, physiologically compatible salts thereof have been found to be of use in combating abnormal cell proliferation.The compounds of formula I may be prepared by reaction of a 5-halo- or 5-trifluoromethyl-pyrimidin-2-one with an appropriate isocyanate.
    Type: Grant
    Filed: September 10, 1982
    Date of Patent: October 23, 1984
    Assignee: Nyegaard & Co. A/S
    Inventors: Tore Benneche, Mikkel Gacek, Kjell Undheim
  • Patent number: 4399140
    Abstract: Compounds of the formula: ##STR1## wherein X represents a halogen atom;R.sup.1 and R.sup.2, which may be same or different, each represents a hydrogen atom, or a C.sub.1-4 alkyl group;Het represents a C-attached 3-9 membered, saturated, unsaturated or aromatic heterocyclic ring containing one or more hetero atoms selected from O, N and S and optionally carrying a fused ring and/or optionally substituted by one or more substituents selected from halogen atoms and hydroxy, C.sub.1-4 alkoxy, amino, acylamino, nitro, oxo, C.sub.1-4 alkyl groups and monocyclic carbocyclic and heterocyclic aryl groups having 5 to 8 ring members; such a heterocyclic ring being saturated and having only a single heteroatom when there are 3 or 4 ring members; andalk represents a C.sub.
    Type: Grant
    Filed: January 6, 1981
    Date of Patent: August 16, 1983
    Assignee: Nyegaard & Co. A/S
    Inventors: Mikkel Gacek, Kjell Undheim