Patents by Inventor Mikkel Norholm

Mikkel Norholm has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for quantification of microRNAs and small interfering RNAs
    Patent number: 8383344
    Abstract: The invention relates to ribonucleic acids, probes and methods for detection, quantification as well as monitoring the expression of mature microRNAs and small interfering RNAs (siRNAs). The invention furthermore relates to methods for monitoring the expression of other non-coding RNAs, mRNA splice variants, as well as detecting and quantifying RNA editing, allelic variants of single transcripts, mutations, deletions, or duplications of particular exons in transcripts, e.g., alterations associated with human disease such as cancer. The invention furthermore relates to methods for detection, quantification as well as monitoring the expression of deoxy nucleic acids.
    Type: Grant
    Filed: June 1, 2009
    Date of Patent: February 26, 2013
    Assignee: Exiqon A/S
    Inventors: Nana Jacobsen, Lars Kongsbak, Sakari Kauppinen, Søren Morgenthaler Echwald, Peter Mouritzen, Peter Stein Nielsen, Mikkel Nørholm
  • Methods for quantification of microRNAs and small interfering RNAs
    Patent number: 8192937
    Abstract: The invention relates to ribonucleic acids, probes and methods for detection, quantification as well as monitoring the expression of mature microRNAs and small interfering RNAs (siRNAs). The invention furthermore relates to methods for monitoring the expression of other non-coding RNAs, mRNA splice variants, as well as detecting and quantifying RNA editing, allelic variants of single transcripts, mutations, deletions, or duplications of particular exons in transcripts, e.g., alterations associated with human disease such as cancer. The invention furthermore relates to methods for detection, quantification as well as monitoring the expression of deoxy nucleic acids.
    Type: Grant
    Filed: April 7, 2005
    Date of Patent: June 5, 2012
    Assignee: Exiqon A/S
    Inventors: Nana Jacobsen, Lars Kongsbak, Sakari Kauppinen, Søren Morgenthaler Echwald, Peter Mouritzen, Peter Stein Nielsen, Mikkel Nørholm
  • NOVEL METHODS FOR QUANTIFICATION OF MICRORNAS AND SMALL INTERFERING RNAS
    Publication number: 20110076675
    Abstract: The invention relates to ribonucleic acids, probes and methods for detection, quantification as well as monitoring the expression of mature microRNAs and small interfering RNAs (siRNAs). The invention furthermore relates to methods for monitoring the expression of other non-coding RNAs, mRNA splice variants, as well as detecting and quantifying RNA editing, allelic variants of single transcripts, mutations, deletions, or duplications of particular exons in transcripts, e.g., alterations associated with human disease such as cancer. The invention furthermore relates to methods for detection, quantification as well as monitoring the expression of deoxy nucleic acids.
    Type: Application
    Filed: June 1, 2009
    Publication date: March 31, 2011
    Applicant: EXIQON A/S
    Inventors: Nana Jacobsen, Lars Kongsbak, Sakari Kauppinen, Søren Morgenthaler Echwald, Peter Mouritzen, Peter Stein Nielsen, Mikkel Nørholm
  • Oligonucleotide probes useful for detection and analysis of microrna precursors
    Publication number: 20090023221
    Abstract: The invention relates to ribonucleic acids and oligonucleotide probes useful for detection and analysis of microRNA precursors and their targets. The invention furthermore relates to oligonucleotide probes for detection and analysis of other non-coding RNAs, mRNAs, mRNA splice variants, allelic variants of single transcripts, mutations, deletions, or duplications of particular exons in transcripts, e.g., alterations associated with human disease, such as cancer.
    Type: Application
    Filed: May 16, 2007
    Publication date: January 22, 2009
    Applicant: Exigon A/S
    Inventors: Gregor Obernosterer, Nina Stahlberg, Soren Moller, Soren M. Echwald, Peter Mouritzen, Peter S. Nielsen, Mikkel Norholm, Kim Bundvig Barken
  • Extendable probes
    Publication number: 20060014183
    Abstract: The invention relates to probes which are extendable useful as PCR probes and in probe libraries. The invention further relates to prevention of replication of a primer extension product in PCR reactions.
    Type: Application
    Filed: June 10, 2005
    Publication date: January 19, 2006
    Inventors: Henrik Pfundheller, Michael Meldgaard, Peter Mouritzen, Peter Nielsen, Mikkel Norholm, Soren Echwald
  • Novel methods for quantification of microRNAs and small interfering RNAs
    Publication number: 20050272075
    Abstract: The invention relates to ribonucleic acids, probes and methods for detection, quantification as well as monitoring the expression of mature microRNAs and small interfering RNAs (siRNAs). The invention furthermore relates to methods for monitoring the expression of other non-coding RNAs, mRNA splice variants, as well as detecting and quantifying RNA editing, allelic variants of single transcripts, mutations, deletions, or duplications of particular exons in transcripts, e.g., alterations associated with human disease such as cancer. The invention furthermore relates to methods for detection, quantification as well as monitoring the expression of deoxy nucleic acids.
    Type: Application
    Filed: April 7, 2005
    Publication date: December 8, 2005
    Inventors: Nana Jacobsen, Lars Kongsbak, Sakari Kauppinen, Soren Echwald, Peter Mouritzen, Peter Nielsen, Mikkel Norholm
  • Slide for use in chemical or biochemical procedures
    Patent number: D495806
    Type: Grant
    Filed: February 7, 2003
    Date of Patent: September 7, 2004
    Assignee: Exiqon A/S
    Inventor: Mikkel Nørholm