Abstract: The present disclosure relates to a novel process for production of crystalline particles of nitrofurantoin anhydrate, the crystalline particles of nitrofurantoin anhydrate being obtained by a process as disclosed, and pharmaceutical compositions as disclosed including crystalline particles of nitrofurantoin anhydrate.

Abstract: The invention relates to pharmaceutical aqueous compositions, for example solutions, comprising ropinirole or a pharmaceutically acceptable salt thereof as an active ingredient the composition having reduced iron content. The compositions exhibit improved chemical stability of the active ingredient. The compositions can be used, for example, in the preparation of eye drop compositions for inducing emesis in animals, particularly companion animals such as dogs and cats, in situations where vomiting is desired.

Abstract: A method for controlling a chemical recovery boiler. The method includes measuring concentrations of sodium carbonate, sodium sulfide, and sodium sulfate from green liquor of the chemical recovery boiler, determining a target temperature for smelt, imaging at least an area of a char bed of the chemical recovery boiler, the area being close to a smelt spout, to obtain an image of the area, determining a measured temperature of the char bed using the image of the area. The method further includes determining that the measured temperature of the char bed is less than the target temperature for smelt, and controlling the chemical recovery boiler such that the temperature of the char bed increases. A chemical recovery boiler for the same.

Abstract: The present disclosure relates to an improved process for the preparation of isochroman structured alpha2A adrenoceptor agonist, namely 2-(5-methoxyisochroman-1-yl)-4,5-dihydro-1H-imidazole of formula (I) and a pharmaceutically acceptable salts thereof, such as 2-(5-methoxyisochroman-1-yl)-4,5-dihydro-1H-imidazole hydrogensulfate of formula (Ia), and to a novel intermediate compound used in the process, namely N-(2-aminoethyl)-5-methoxyisochroman-1-carboxamide monohydrate of formula (V). Alpha2A agonists are useful in the treatment of anxiety, and for use as a sedative or analgesic agent, and other diseases where alpha2A agonism is desired.

Abstract: The present disclosure relates to an improved process for the preparation of isochroman structured alpha2A adrenoceptor agonist, namely 2-(5-methoxyisochroman-1-yl)-4,5-dihydro-1H-imidazole of formula (I) and a pharmaceutically acceptable salts thereof, such as 2-(5-methoxyisochroman-1-yl)-4,5-dihydro-1H-imidazole hydrogensulfate of formula (Ia), and to a novel intermediate compound used in the process, namely N-(2-aminoethyl)-5-methoxyisochroman-1-carboxamide monohydrate of formula (V). Alpha2A agonists are useful in the treatment of anxiety, and for use as a sedative or analgesic agent, and other diseases where alpha2A agonism is desired.

Abstract: A method for optimizing reduction and content of total titratable alkali of green liquor of a recovery boiler. The method comprises producing green liquor in a dissolving tank by conveying smelt and weak white liquor into the dissolving tank and measuring at least the contents of sodium sulphate, sodium hydroxide, sodium sulphide, and sodium carbonate of the green liquor. The method comprises controlling at least a process parameter of a recovery boiler to maximize the reduction of the recovery boiler and controlling the flow of the weak white liquor into the dissolving tank to optimize the content of total titratable alkali of the green liquor. In addition, a system for producing green liquor with optimized reduction and content of total titratable alkali. The system comprises a first sensor arrangement, a first and a second regulator, and a processing unit arrangement configured to perform the method.

Abstract: A method for optimizing reduction and content of total titratable alkali of green liquor of a recovery boiler. The method comprises producing green liquor in a dissolving tank by conveying smelt and weak white liquor into the dissolving tank and measuring at least the contents of sodium sulphate, sodium hydroxide, sodium sulphide, and sodium carbonate of the green liquor. The method comprises controlling at least a process parameter of a recovery boiler to maximize the reduction of the recovery boiler and controlling the flow of the weak white liquor into the dissolving tank to optimize the content of total titratable alkali of the green liquor. In addition, a system for producing green liquor with optimized reduction and content of total titratable alkali. The system comprises a first sensor arrangement, a first and a second regulator, and a processing unit arrangement configured to perform the method.

Abstract: A method and apparatus for sootblowing a recovery boiler. Sootblowers of the recovery boiler are divided into sootblowing groups, and a sootblowing interval is determined for the sootblowers. A fouling index is produced for each sootblowing group of the recovery boiler, and relative frequency values are calculated.

Abstract: A method and apparatus for sootblowing a recovery boiler. Sootblowers of the recovery boiler are divided into sootblowing groups, and a sootblowing interval is determined for the sootblowers. A fouling index is produced for each sootblowing group of the recovery boiler, and relative frequency values are calculated.

Abstract: A multichannel pipette is disclosed having an improved arrangement of replaceable tip containers in which the individual tip containers are connected together by flexible connecting members which are deformable to permit connection of the tip containers to differing configurations of tip cones.