Abstract: A steering system for a motor vehicle includes at least one securing member and a first bearing device. The securing member releases the first bearing device from a fastening in the first position when applying a predetermined force on the first bearing device and the first bearing device can be moved into a second position.

Abstract: A steering system for a motor vehicle includes a steering column and a device for adjusting the steering column. The device includes a bearing block, a first guide mechanism, and a second guide mechanism. A housing of the steering column is adjustably mounted in the bearing block. The first guide mechanism is configured to adjust a height of the steering column in the bearing block. The second guide mechanism is configured to adjust an inclination of the housing, and includes at least one first guide plate and at least one second guide plate that are each movably connected to the housing of the steering column and to the bearing block so as to be axially movable with an adjustment of the inclination of the housing.

Abstract: A steering system for a motor vehicle includes a steering column and a device for adjusting the steering column. The device includes a bearing block, a first guide mechanism, and a second guide mechanism. A housing of the steering column is adjustably mounted in the bearing block. The first guide mechanism is configured to adjust a height of the steering column in the bearing block. The second guide mechanism is configured to adjust an inclination of the housing, and includes at least one first guide plate and at least one second guide plate that are each movably connected to the housing of the steering column and to the bearing block so as to be axially movable with an adjustment of the inclination of the housing.

Abstract: The invention provides a method of targeting T-cells to tumor cells using a tumor-associated antigen (TAA) specific antibody and a T-cell specific antibody, wherein the two antibodies can bind to each other through a high affinity avidin/biotin or streptavidin/biotin connection. The invention further provides methods to target activated T-cells to different tumor types by using a T-cell specific antibody that is specific to an activated T-cell surface molecule like CTLA-4.

Abstract: The invention provides a method of targeting T-cells to tumor cells using a tumor-associated antigen (TAA) specific antibody and a T-cell specific antibody, wherein the two antibodies can bind to each other through a high affinity avidin/biotin or streptavidin/biotin connection. The invention further provides methods to target activated T-cells to different tumor types by using a T-cell specific antibody that is specific to an activated T-cell surface molecule like CTLA-4.

Abstract: The subject of the present invention is the provision of new salts of duloxetine of the Formula (I) with organic acids, process for their preparation and medicinal products containing thereof. The new salts are essentially free from the impurity of the Formula (II) and possess high purity and high stability. The new duloxetine salts are prepared by reacting duloxetine free base dissolved in an organic solvent with an approximately equimolar amount of an organic acid. Particularly advantageous crystalline salts are those formed with fumaric acid, citric acid or (?)-mandelic acid.

Abstract: The invention relates to biological microbeads, and in certain embodiments, to the use thereof in flow-cytometric applications. Biological microbeads are fixed cells that may be surface-modified with proteins or other molecules that have specific binding properties. These surface-bound proteins may bind to target compounds bearing fluorescent labels that facilitate detection by flow cytometry. Provided are compositions and methods for the use of biological microbeads as an inexpensive alternative to synthetic microbeads for in an extensive number of flow-cytometric applications, including quantitative PCR, detection of nucleases, detection of proteases, and immunoassays.

Abstract: A process for the hygienic extraction and separate collection of animal blood fit and unfit for consumption, comprises stunning the animals prior to stabbing and providing the animals with serial numbers suitable for identification of the carcass and the blood to be extracted. The spot of stabbing on the throat of the animals is disinfected and the animals are cyclically stepped into a stabbing position. The animal is stabbed in the stabbing position with a disinfected stabbing tool which is exchanged for each animal and is provided with a closed outlet a hose-fitted hollow knife. The hygenic blood is extracted through the stabbing tool into one of a plurality of rotating blood collecting tanks arranged on a turntable and moved into an extracting position. An anticoagulant is added to the blood by gravity feed and after filling, the tanks are advanced toward into a first draining position for blood fit for consumption.

Abstract: The invention relates to an apparatus for and a method of spreading gaseous, liquid and powdered materials, that are applicable to pressing out creamy or foamy materials, too. According to the method a material to be spread is placed in a tank into the pressure vessel, overpressure is developed in the pressure vessel for spreading, whereby the tank moves towards the spreading nozzle and the spreading nozzle is communicated with the interior of the tank. The apparatus comprises a pressure vessel with its interior space divided into two sections, one of them contains the fuel tank ensuring the overpressure, the other one contains the material tank sealing airtightly the first section. The invention provides reliable spreading, not polluting the environment, the pressure vessel of the apparatus is not to be thrown away, and the tanks inside the vessel are replaceable.