Patents by Inventor Miklos Krepuska

Miklos Krepuska has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of modulating erythropoiesis with arginine vasopressin receptor 1B molecules
    Patent number: 10172911
    Abstract: Disclosed are methods of modulating erythropoiesis with arginine vasopressin receptor 1B (AVPR1B) molecules, such as AVPR1B agonists or antagonists. In one example, a method of stimulating erythropoiesis is disclosed including administering an effective amount of an AVPR1B stimulatory molecule to a subject in need thereof, thereby stimulating erythropoiesis. Also disclosed is a method of stimulating hematopoetic stem cell (HSC) proliferation which includes administering an effective amount of an AVPR1B stimulatory molecule to a subject in need thereof, thereby stimulating HSC proliferation. A method of inhibiting HSC proliferation including administering an effective amount of an AVPR1B inhibitory molecule to a subject in need thereof, thereby inhibiting HSC proliferation is provided.
    Type: Grant
    Filed: October 1, 2014
    Date of Patent: January 8, 2019
    Assignee: The United States of America, as represented by the Secretary, Department of Health and Human Services
    Inventors: Eva M. Mezey, Balazs Mayer, Krisztian Nemeth, Miklos Krepuska
  • METHODS OF MODULATING ERYTHROPOIESIS WITH ARGININE VASOPRESSIN RECEPTOR 1B MOLECULES
    Publication number: 20160220631
    Abstract: Disclosed are methods of modulating erythropoiesis with arginine vasopressin receptor 1B (AVPR1B) molecules, such as AVPR1B agonists or antagonists. In one example, a method of stimulating erythropoiesis is disclosed including administering an effective amount of an AVPR1B stimulatory molecule to a subject in need thereof, thereby stimulating erythropoiesis. Also disclosed is a method of stimulating hematopoetic stem cell (HSC) proliferation which includes administering an effective amount of an AVPR1B stimulatory molecule to a subject in need thereof, thereby stimulating HSC proliferation. A method of inhibiting HSC proliferation including administering an effective amount of an AVPR1B inhibitory molecule to a subject in need thereof, thereby inhibiting HSC proliferation is provided.
    Type: Application
    Filed: October 1, 2014
    Publication date: August 4, 2016
    Applicant: The USA, as represented by the Secretary, Departm- ent of Health and Human Service
    Inventors: Eva M. Mezey, Balazs Mayer, Krisztian Nemeth, Miklos Krepuska