Patents by Inventor Mi-Kyung Shin

Mi-Kyung Shin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pharmaceutical composition containing (R)-N-[1-(3,5-difluoro-4-methansulfonylamino-phenyl)-ethyl]-3-(2-propyl-6-trifluoromethyl-pyridin-3-yl)-acrylamide
    Patent number: 11957669
    Abstract: One aspect of the present disclosure is a pharmaceutical composition which includes (R)—N-[1-(3,5-difluoro-4-methansulfonylamino-phenyl)-ethyl]-3-(2-propyl-6-trifluoromethyl-pyridin-3-yl)-acrylamide as a first component and a cellulosic polymer as a second component, wherein the composition of one aspect of the present disclosure has a formulation characteristic in which crystal formation is delayed for a long time.
    Type: Grant
    Filed: August 10, 2018
    Date of Patent: April 16, 2024
    Assignee: AMOREPACIFIC CORPORATION
    Inventors: Joon Ho Choi, Won Kyung Cho, Kwang-Hyun Shin, Byoung Young Woo, Ki-Wha Lee, Min-Soo Kim, Jong Hwa Roh, Mi Young Park, Young-Ho Park, Eun Sil Park, Jae Hong Park
  • Supramolecular hydrogel applications to the carotid bodies to treat hypertension and sleep apnea in obesity
    Patent number: 11819481
    Abstract: The present invention provides compositions and methods for treating hypertension and obstructive sleep apnea utilizing hydrogel compositions comprising drug amphiphiles with TRPM 7 antagonists for use in a subject, including use on the carotid body of a subject.
    Type: Grant
    Filed: January 24, 2022
    Date of Patent: November 21, 2023
    Assignee: THE JOHNS HOPKINS UNIVERSITY
    Inventors: Vsevolod Polotsky, Honggang Cui, Roxana Elena Mitrut, Mi-kyung Shin
  • SUPRAMOLECULAR HYDROGEL APPLICATIONS TO THE CAROTID BODIES TO TREAT HYPERTENSION AND SLEEP APNEA IN OBESITY
    Publication number: 20220241219
    Abstract: The present invention provides compositions and methods for treating hypertension and obstructive sleep apnea utilizing hydrogel compositions comprising drug amphiphiles with TRPM 7 antagonists for use in a subject, including use on the carotid body of a subject.
    Type: Application
    Filed: January 24, 2022
    Publication date: August 4, 2022
    Inventors: Vsevolod Polotsky, Honggang Cui, Roxana Elena Mitrut, Mi-kyung Shin
  • Supramolecular hydrogel applications to the carotid bodies to treat hypertension and sleep apnea in obesity
    Patent number: 11229614
    Abstract: The present invention provides compositions and methods for treating hypertension and obstructive sleep apnea utilizing hydrogel compositions comprising drug amphiphiles with TRPM 7 antagonists for use in a subject, including use on the carotid body of a subject.
    Type: Grant
    Filed: December 19, 2018
    Date of Patent: January 25, 2022
    Assignee: THE JOHNS HOPKINS UNIVERSITY
    Inventors: Vsevolod Polotsky, Honggang Cui, Roxana Elena Mitrut, Mi-kyung Shin
  • SUPRAMOLECULAR HYDROGEL APPLICATIONS TO THE CAROTID BODIES TO TREAT HYPERTENSION AND SLEEP APNEA IN OBESITY
    Publication number: 20210052520
    Abstract: The present invention provides compositions and methods for treating hypertension and obstructive sleep apnea utilizing hydrogel compositions comprising drug amphiphiles with TRPM 7 antagonists for use in a subject, including use on the carotid body of a subject.
    Type: Application
    Filed: December 19, 2018
    Publication date: February 25, 2021
    Inventors: Vsevolod Polotsky, Honggang Cui, Roxana Elena Mitrut, Mi-kyung Shin
  • Rapid screening method of translational fusion partners for producing recombinant proteins and translational fusion partners screened therefrom
    Patent number: 9012367
    Abstract: Disclosed are a method for rapid screening of suitable translational fusion partners (TFPs) capable of inducing expression or secretory production of non-producible proteins, which are difficult to produce in conventional recombinant production methods, from a variety of genetic sources, and protein secretion-inducing TFPs obtained using the method.
    Type: Grant
    Filed: January 30, 2014
    Date of Patent: April 21, 2015
    Assignee: Korea Research Institute of Bioscience and Biotechnology
    Inventors: Jung-Hoon Sohn, Eui-Sung Choi, Jung-Hoon Bae, Eung-Suck Lee, Mi-Kyung Shin
  • Library of translational fusion partners for producing recombinant proteins and translational fusion partners screened therefrom
    Patent number: 8865629
    Abstract: The invention relates to techniques for the rapid screening of suitable translational fusion partners (TFPs) capable of inducing secretory production of recombinant proteins, especially proteins that are difficult to produce using conventional recombinant production methods.
    Type: Grant
    Filed: July 13, 2006
    Date of Patent: October 21, 2014
    Assignee: Korea Research Institute of Bioscience and Biotechnology
    Inventors: Jung-Hoon Sohn, Eui-Sung Choi, Jung-Hoon Bae, Mi-Kyung Shin, Sung-Sook Yoon, Chang-Soo Chun
  • Rapid Screening Method of Translational Fusion Partners for Producing Recombinant Proteins and Translational Fusion Partners Screened Therefrom
    Publication number: 20140220631
    Abstract: Disclosed are a method for rapid screening of suitable translational fusion partners (TFPs) capable of inducing expression or secretory production of non-producible proteins, which are difficult to produce in conventional recombinant production methods, from a variety of genetic sources, and protein secretion-inducing TFPs obtained using the method.
    Type: Application
    Filed: January 30, 2014
    Publication date: August 7, 2014
    Applicant: KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY
    Inventors: Jung-Hoon SOHN, Eui-Sung CHOI, Jung-Hoon BAE, Eung-Suck LEE, Mi-Kyung SHIN
  • Rapid screening method of translational fusion partners for producing recombinant proteins and translational fusion partners screened therefrom
    Patent number: 8673822
    Abstract: Disclosed are a method for rapid screening suitable translational fusion partners (TFPs) capable of inducing expression or secretory production of non-producible proteins, which are difficult to produce in conventional recombinant production methods, from a variety of genetic sources, and protein secretion-inducing TFPs obtained using the method.
    Type: Grant
    Filed: December 30, 2004
    Date of Patent: March 18, 2014
    Assignee: Korea Research Institute of Bioscience and Biotechnology
    Inventors: Jung-Hoon Sohn, Eui-Sung Choi, Jung-Hoon Bae, Eung-Suck Lee, Mi-Kyung Shin
  • Library of Translational Fusion Partners for Producing Recombinant Proteins and Translational Fusion Partners Screened Therefrom
    Publication number: 20090181425
    Abstract: The invention relates to techniques for the rapid screening of suitable translational fusion partners (TFPs) capable of inducing secretory production of recombinant proteins, especially proteins that are difficult to produce using conventional recombinant production methods.
    Type: Application
    Filed: July 13, 2006
    Publication date: July 16, 2009
    Applicant: Korea Research Institute Of Bioscience and Biotechnology
    Inventors: Jung-Hoon Sohn, Eui-Sung Choi, Jung-Hoon Bae, Mi-Kyung Shin, Sung-Sook Yoon, Chang-Soo Chun
  • Rapid Screening Method of Translational Fusion Partners for Producing Recombinant Proteins and Translational Fusion Partners Screened Therefrom
    Publication number: 20070275385
    Abstract: Disclosed are a method for rapid screening suitable translational fusion partners (TFPs) capable of inducing expression or secretory production of non-producible proteins, which are difficult to produce in conventional recombinant production methods, from a variety of genetic sources, and protein secretion-inducing TFPs obtained using the method.
    Type: Application
    Filed: December 30, 2004
    Publication date: November 29, 2007
    Applicant: Korea Research Institute of Bioscience and Biotechnology
    Inventors: Jung-Hoon Sohn, Eui-Sung Choi, Jung-Hoon Bae, Eung-Suck Lee, Mi-Kyung Shin