Abstract: Systems, methods and a non-transitory computer readable medium for ischemic cerebrovascular event risk assessment from a vascular image of a patient are described. The vascular image of the patient includes at least a vessel and atherosclerotic plaque in the vessel and the method includes extracting hemodynamic information of the patient from the vascular image and extracting plaque information of the patient from the vascular image. The method also includes outputting a result indicating a risk of the ischemic cerebrovascular event using an artificial intelligence model based on one or both of the hemodynamic information and the plaque information. The system includes a medical imaging device, at least one processor and at least one memory.