Abstract: Composition intended for buccal absorption of nicotine into the system circulation and distribution to the central nervous system for the purpose of smoking cessation or nicotine substitution in conditions adverse for smoking according to the invention contains nicotine solution in form of a base and/or its salt with organic acid in concentration 0.01 to 8.00% by weight and substances with mucolytic effect. Single application dosage contains 0.05 to 3.00 mg of nicotine. A method for administering is also provided.

Abstract: Composition intended for buccal absorption of nicotine into the system circulation and distribution to the central nervous system for the purpose of smoking cessation or nicotine substitution in conditions adverse for smoking according to the invention contains nicotine solution in form of a base and/or its salt with organic acid in concentration 0.01 to 8.00% by weight and substances with mucolytic effect. Single application dosage contains 0.05 to 3.00 mg of nicotine.

Abstract: Biodegradable antitumor composition with prolonged release has at least one antitumor agent and a biodegradable oligoester carrier, having a numeric mean relative molecular mass Mn of from 650 to 7,500, a mass mean relative molecular mass Mw from 800 to 10,000 and a glass transition temperature Tg from ?35 to 45° C. The carrier is prepared by polycondensation reaction of polyhydric alcohol containing at least 3 hydroxy groups with at least one aliphatic ?-hydroxy acid in the molar ratio of polyhydric alcohol to aliphatic ?-hydroxy acid of from 0.5:99.5 to 12:88, and is a polyhydric alcohol to the hydroxy groups of which chains created from several molecules of at least one aliphatic ?-hydroxy acid are bound by ester bonds.