Abstract: There is disclosed system for oxygenating a patient in relation to anaesthesia using high flow gas delivery. The system has a flow source, and a controller for determining oxygenation requirements of the patient before or during anaesthesia. A method of oxygenating a patient in relation to anaesthesia using high flow gas delivery is also disclosed. The method determines oxygenation requirements of the patient before or during anaesthesia.

Abstract: The invention relates to a respiratory system comprising a first patient interface for delivery of a first flow of gases to a patient, a second patient interface for delivery of a second flow of gases to the patient, and a device and/or sensing arrangement that is configure to facilitate a switching of the system between a first respiratory mode where the device allowing delivery of the first flow of gases to an outlet of the first patient interface when the second patient interface is absent from the patient, and a second respiratory mode where the device reducing or stopping delivery of the first flow of gases to the outlet of the first patient interface when the second patient interface is located together with the first patient interface upon the patient.

Abstract: A pulsed field ablation catheter for use in atrial fibrillation treatment having a distal steerable variable loop with multiple electrodes coupled to the distal end of a multilumen shaft and a handle coupled to the proximal end of the multilumen shaft. A shape imparting mechanism coupled to the handle is configured to change the shape of steerable loop by manipulating a steering mechanism to steer the steerable loop to the treatment site and a rotational actuator to change the diameter of the variable loop to better interface with varying human anatomy.

Abstract: Nasal cannula assemblies for providing respiratory therapy to patients are provided. A nasal cannula assembly can include a cannula, an optional manifold which may be removable, a gas supply tube, and a securement mechanism. Securement mechanisms can include headgear straps, cheek pads, or an adhesive nose strip. A nasal cannula assembly can also include a lanyard, lanyard clip, and/or lanyard connector to help support the weight of a main gas delivery conduit.

Abstract: This invention relates to headgear and a patient interface, or components of a headgear or patient interface, such as a nasal cannula. In one embodiment is a size adjustable headstrap to be provided as a headgear or a part thereof, in another is a portion of a headstrap or component for association therewith in which the portion or component facilitates improved location of the strap upon a user's face, in another embodiment is a system for encapsulating or covering a connector from contact with a user's face or facial skin, in another embodiment is a face mount part or body for a patient interface of a particular configuration, and in yet a further embodiment is a gases flow manifold for delivering of gases to a patient interface of a particular configuration for improved patient comfort.

Abstract: This invention relates to headgear and a patient interface, or components of a headgear or patient interface, such as a nasal cannula. In one embodiment is a size adjustable headstrap to be provided as a headgear or a part thereof, in another is a portion of a headstrap or component for association therewith in which the portion or component facilitates improved location of the strap upon a user's face, in another embodiment is a system for encapsulating or covering a connector from contact with a user's face or facial skin, in another embodiment is a face mount part or body for a patient interface of a particular configuration, and in yet a further embodiment is a gases flow manifold for delivering of gases to a patient interface of a particular configuration for improved patient comfort.

Abstract: A method of determining a duration of safe apnoea. Information is obtained relating to a respiratory indicator, and a duration of safe apnoea is determined from the obtained information. A respiratory therapy system has one or more patient interfaces. A processor is configured to determine a duration of safe apnoea based on obtained information relating to a respiratory indicator.

Abstract: Described is an apparatus for oxygenation and/or CO2 clearance of a patient, comprising: a flow source or a connection for a flow source for providing a gas flow, a gas flow modulator, a controller to control the gas flow, wherein the controller is operable to: receive input relating to heart activity and/or trachea gas flow of the patient, and control the gas flow modulator to provide a varying gas flow with one or more oscillating components with a frequency or frequencies based on the heart activity and/or trachea flow of the patient.

Abstract: The disclosure relates to a nasal cannula comprising a port configured for delivery of a medicament into a flow of a fluid being delivered by the nasal cannula to a user and/or configured for interfacing with a medicament delivery device or an instrument. The disclosure also relates to a nasal cannula comprising an asymmetric profile to reduce an amount of occlusion of one nare of a user to provide access for an instrument to the nare with the nasal cannula in use.

Abstract: Described is an apparatus for oxygenation and/or CO2 clearance of a patient, comprising: a flow source or a connection for a flow source for providing a gas flow, a gas flow modulator, a controller to control the gas flow, wherein the controller is operable to: receive input relating to heart activity and/or trachea gas flow of the patient, and control the gas flow modulator to provide a varying gas flow with one or more oscillating components with a frequency or frequencies based on the heart activity and/or trachea flow of the patient.

Abstract: A method of determining a duration of safe apnoea. Information is obtained relating to a respiratory indicator, and a duration of safe apnoea is determined from the obtained information. A respiratory therapy system has one or more patient interfaces. A processor is configured to determine a duration of safe apnoea based on obtained information relating to a respiratory indicator.

Abstract: A user interface convertible between a nasal configuration and an oral configuration. The user interface has a nasal cannula and a mouthpiece. The nasal cannula has a body portion and at least one prong extending from the body portion, the prong being adapted to direct a flow of gas into a nare of a user's nose. The mouthpiece is adapted to engage the mouth of the patient and direct a flow of gas into a user's mouth. In the nasal configuration the prong of the nasal cannula is adapted to direct a flow of gases into a nare of the patient. In the oral configuration, the nasal cannula is engaged with the mouthpiece such that a gases flow is provided to at least the mouth of the user.

Abstract: The disclosure relates to a nasal cannula comprising a port configured for delivery of a medicament into a flow of a fluid being delivered by the nasal cannula to a user and/or configured for interfacing with a medicament delivery device or an instrument. The disclosure also relates to a nasal cannula comprising an asymmetric profile to reduce an amount of occlusion of one nare of a user to provide access for an instrument to the nare with the nasal cannula in use.

Abstract: A user interface convertible between a nasal configuration and an oral configuration. The user interface has a nasal cannula and a mouthpiece. The nasal cannula has a body portion and at least one prong extending from the body portion, the prong being adapted to direct a flow of gas into a nare of a user's nose. The mouthpiece is adapted to engage the mouth of the patient and direct a flow of gas into a user's mouth. In the nasal configuration the prong of the nasal cannula is adapted to direct a flow of gases into a nare of the patient. In the oral configuration, the nasal cannula is engaged with the mouthpiece such that a gases flow is provided to at least the mouth of the user.

Abstract: A method of determining a duration of safe apnoea. Information is obtained relating to a respiratory indicator, and a duration of safe apnoea is determined from the obtained information. A respiratory therapy system has one or more patient interfaces. A processor is configured to determine a duration of safe apnoea based on obtained information relating to a respiratory indicator.

Abstract: This invention relates to a patient interface and component parts which may be integrated or form a part of an assembled interface for use by a user. In various embodiments, the component parts may include: a component may be provided as a clip for supporting a gas supply tube to the interface; a buckle may be provided at an end of a headgear strap for releasable attachment to the interface; a manifold part of a patient interface may be attachable to the interface in a manner allowing for adjustment or re-orientation such that an associated gas supply conduit is re-routed to be to a left- or a right-side of the interface (or user); one or a pair of support side arms of the interface may be configured to be twisted or bent so as to more comfortably accommodate the shape of a user's face upon which they are to be located in use; parts of a manifold at the connection of a gas supply tube to the interface may be configured to be of a multi-part manifold assembly.

Abstract: The present disclosure relates to determining a corrected exhaled gas measurement during high flow respiratory therapy. Measuring exhaled gas concentration during high flow respiratory therapy is difficult and inaccurate due to a phenomenon known as flushing. The high flows delivered to the patient flush the dead space in the conducting airways, which causes a dilution effect that results in underestimated or overestimated exhaled gas measurement depending on the gas composition delivered by the high flow system. This can lead to incorrect clinical measurements and diagnoses. Various algorithms are disclosed herein to account for the dilution effect caused by flushing, allowing for the method of measuring gas concentrations to still be used accurately for clinical measurements.

Abstract: The invention relates to a respiratory system comprising a first patient interface for delivery of a first flow of gases to a patient, a second patient interface for delivery of a second flow of gases to the patient, and a device and/or sensing arrangement that is configure to facilitate a switching of the system between a first respiratory mode where the device allowing delivery of the first flow of gases to an outlet of the first patient interface when the second patient interface is absent from the patient, and a second respiratory mode where the device reducing or stopping delivery of the first flow of gases to the outlet of the first patient interface when the second patient interface is located together with the first patient interface upon the patient.

Abstract: This invention relates to a respiratory therapy system comprising a first patient interface for delivery of a flow of gas to a patient, and a second patient interface for delivery of a flow of gas to the patient, or devices or interfaces for use in such systems.

Abstract: A patient interface and component parts which may include: a component such as a clip for supporting a gas supply tube to the interface; a buckle may be provided at an end of a headgear strap for releasable attachment to the interface; a manifold part of a patient interface may be attachable to the interface in a manner allowing for adjustment or re-orientation such that an associated gas supply conduit is re-routed to be to a left- or a right-side of the interface (or user); one or a pair of support side arms of the interface may be configured to be twisted or bent so as to more comfortably accommodate the shape of a user's face upon which they are to be located in use; parts of a manifold at the connection of a gas supply tube to the interface may be configured to be of a multi-part manifold assembly.