Patents by Inventor Milen Shishkov
Milen Shishkov has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 11660001Abstract: Arrangements, apparatus, systems and systems are provided for obtaining data for at least one portion within at least one luminal or hollow sample. The arrangement, system or apparatus can be (insertable via at least one of a mouth or a nose of a patient. For example, a first optical arrangement can be configured to transceive at least one electromagnetic (e.g., visible) radiation to and from the portion. A second arrangement may be provided at least partially enclosing the first arrangement. Further, a third arrangement can be configured to be actuated so as to position the first arrangement at a predetermined location within the luminal or hollow sample. The first arrangement may be configured to compensate for at least one aberration (e.g., astigmatism) caused by the second arrangement and/or the third arrangement. The second arrangement can include at least one portion which enables a guiding arrangement to be inserted there through.Type: GrantFiled: December 22, 2020Date of Patent: May 30, 2023Assignee: The General Hospital CorporationInventors: Guillermo J. Tearney, Milen Shishkov, Brett Eugene Bouma, Benjamin J. Vakoc, Norman S. Nishioka
-
Patent number: 11553841Abstract: Exemplary systems, devices, methods, apparatus and computer-accessible media for providing and/or utilizing optical frequency domain imaging (OFDI) and fluorescence of structures and, e.g., multimodality imaging using OFDI techniques and fluorescence imaging techniques are described. For example, an arrangement can provide at least one electro-magnetic radiation to an anatomical structure. Such exemplary arrangement can include at least one optical core and at least one cladding at least partially surrounding the fiber(s). A region between the optical core(s) and the cladding(s) can have an index that is different from indexes of the optical core(s) and the cladding(s). The arrangement can also include at least one apparatus which is configured to transmit the radiation(s) via the optical core(s) and the cladding(s) to the anatomical structure.Type: GrantFiled: March 3, 2021Date of Patent: January 17, 2023Assignee: The General Hospital CorporationInventors: Guillermo J. Tearney, Brett Eugene Bouma, Hongki Yoo, Milen Shishkov, Joseph Gardecki, Roman Shubochkin, Theodore Morse, Farouc Amin Jaffer
-
Patent number: 11490797Abstract: An exemplary apparatus for obtaining data for at least one portion within at least one luminal or hollow sample can be provided. For example, the apparatus can include a first optical arrangement configured to transceive at least one electromagnetic radiation to and from the portion(s). The apparatus can also include a wavelength dispersive second arrangement, which can be configured to disperse the electromagnetic radiation(s). A housing can be provided with a shape of a pill, and enclosing the first and second arrangements.Type: GrantFiled: May 21, 2013Date of Patent: November 8, 2022Assignee: The General Hospital CorporationInventors: Michalina Gora, Dongkyun Kang, Norman S. Nishioka, Brett Eugene Bouma, Guillermo J. Tearney, Robert Carruth, Kevin Gallagher, Jenny Sauk, Moon Gu Lee, Nima Tabatabaei, Milen Shishkov
-
Patent number: 11363945Abstract: There is provided a new apparatus, system, and method of use for laser speckle imaging that allows for omni-directional viewing. The omni-directional viewing can include a reflector and switches configured for switching the illumination on the luminal tissue such that the light reflected from the luminal tissue at any given time is reflected from one or more substantially non-overlapping sections of a luminal tissue. This apparatus may be particularly useful for tissue analysis such as analysis of vulnerable plaque.Type: GrantFiled: June 19, 2014Date of Patent: June 21, 2022Assignee: The General Hospital CorporationInventors: Masaki Hosoda, Seemantini K. Nadkarni, Milen Shishkov
-
Publication number: 20210267460Abstract: Exemplary systems, devices, methods, apparatus and computer-accessible media for providing and/or utilizing optical frequency domain imaging (OFDI) and fluorescence of structures and, e.g., multimodality imaging using OFDI techniques and fluorescence imaging techniques are described. For example, an arrangement can provide at least one electro-magnetic radiation to an anatomical structure. Such exemplary arrangement can include at least one optical core and at least one cladding at least partially surrounding the fiber(s). A region between the optical core(s) and the cladding(s) can have an index that is different from indexes of the optical core(s) and the cladding(s). The arrangement can also include at least one apparatus which is configured to transmit the radiation(s) via the optical core(s) and the cladding(s) to the anatomical structure.Type: ApplicationFiled: March 3, 2021Publication date: September 2, 2021Inventors: Guillermo J. Tearney, Brett Eugene Bouma, Hongki Yoo, Milen Shishkov, Joseph Gardecki, Roman Shubochkin, Theodore Morse, Farouc Amin Jaffer
-
Publication number: 20210219844Abstract: Arrangements, apparatus, systems and systems are provided for obtaining data for at least one portion within at least one luminal or hollow sample. The arrangement, system or apparatus can be (insertable via at least one of a mouth or a nose of a patient. For example, a first optical arrangement can be configured to transceive at least one electromagnetic (e.g., visible) radiation to and from the portion. A second arrangement may be provided at least partially enclosing the first arrangement. Further, a third arrangement can be configured to be actuated so as to position the first arrangement at a predetermined location within the luminal or hollow sample. The first arrangement may be configured to compensate for at least one aberration (e.g., astigmatism) caused by the second arrangement and/or the third arrangement. The second arrangement can include at least one portion which enables a guiding arrangement to be inserted there through.Type: ApplicationFiled: December 22, 2020Publication date: July 22, 2021Inventors: Guillermo J. Tearney, Milen Shishkov, Brett Eugene Bouma, Benjamin J. Vakoc, Norman S. Nishioka
-
Patent number: 10987000Abstract: Arrangements, apparatus, systems and systems are provided for obtaining data for at least one portion within at least one luminal or hollow sample. The arrangement, system or apparatus can be (insertable via at least one of a mouth or a nose of a patient. For example, a first optical arrangement can be configured to transceive at least one electromagnetic (e.g., visible) radiation to and from the portion. A second arrangement may be provided at least partially enclosing the first arrangement. Further, a third arrangement can be configured to be actuated so as to position the first arrangement at a predetermined location within the luminal or hollow sample. The first arrangement may be configured to compensate for at least one aberration (e.g., astigmatism) caused by the second arrangement and/or the third arrangement. The second arrangement can include at least one portion which enables a guiding arrangement to be inserted there through.Type: GrantFiled: May 8, 2017Date of Patent: April 27, 2021Assignee: The General Hospital CorporationInventors: Guillermo J. Tearney, Milen Shishkov, Brett Eugene Bouma, Benjamin J. Vakoc, Norman S. Nishioka
-
Patent number: 10939825Abstract: Exemplary systems, devices, methods, apparatus and computer-accessible media for providing and/or utilizing optical frequency domain imaging (OFDI) and fluorescence of structures and, e.g., multimodality imaging using OFDI techniques and fluorescence imaging techniques are described. For example, an arrangement can provide at least one electro-magnetic radiation to an anatomical structure. Such exemplary arrangement can include at least one optical core and at least one cladding at least partially surrounding the fiber(s). A region between the optical core(s) and the cladding(s) can have an index that is different from indexes of the optical core(s) and the cladding(s). The arrangement can also include at least one apparatus which is configured to transmit the radiation(s) via the optical core(s) and the cladding(s) to the anatomical structure.Type: GrantFiled: November 22, 2016Date of Patent: March 9, 2021Assignees: The General Hospital Corporation, Trustees of Boston UniversityInventors: Guillermo J. Tearney, Brett Eugene Bouma, Hongki Yoo, Milen Shishkov, Joseph Gardecki, Roman Shubochkin, Theodore Morse, Farouc Amin Jaffer
-
Patent number: 10426548Abstract: According one exemplary embodiment of the present invention, method and system can be provided for applying a laser radiation to at least one portion of a biological structure. For example, a beam of the laser radiation can be provided to the portion, whereas a cross-sectional area of the beam is at most about 1/10th of an entire area of the at least one portion. The beam can be applied to the portion (a) based on a predetermined pattern, (b) while modulating a wavelength of the laser radiation, and/or (c) while monitoring a depth of the application of the laser radiation.Type: GrantFiled: February 1, 2007Date of Patent: October 1, 2019Assignee: The General Hosppital CorporationInventors: Guillermo J. Tearney, Milen Shishkov, Brett Eugene Bouma, Benjamin J. Vakoc
-
Patent number: 10285568Abstract: In accordance with exemplary embodiments of the present disclosure, device and method can be provided which can facilitate imaging of biological tissues, e.g., luminal organs in vivo, using optical techniques. The exemplary device can include different designs an features of one or more catheters, which can illuminate the tissues, and collect signals from the inside of the lumen. In another exemplary embodiment according to the present disclosure, a balloon-catheter can be provided with the flexible neck, which can absorb most of the bending. According to still another exemplary embodiments of the present disclosure, a balloon-catheter tethered capsule can be provided, and according a yet further exemplary embodiment, a structured balloon design can be provided with one or more protuberances, thus enabling imaging of the structures in close contact, e.g., without compressing of the tissue.Type: GrantFiled: June 3, 2011Date of Patent: May 14, 2019Assignee: The General Hospital CorporationInventors: Guillermo J. Tearney, Brett Eugene Bouma, Michalina Gora, Melissa Suter, Hongki Yoo, Milen Shishkov
-
Publication number: 20180010965Abstract: Exemplary apparatus for method for forming at least one spectral encoding endoscopy configuration. For example, it is possible to modify a spacer configuration and an lens optics configuration to have respective predetermined lengths, and also to modify a dispersive optics configuration to have a further predetermined length. Further, the modified spacer and modified lens optics configurations can be attached to one another to form a combined spacer-lens optics configuration. The modified dispersive optics configuration can be attached to a substrate to form to form a grating substrate configuration. Additionally, the combined spacer-lens optics configuration can be connected to an optical fiber, and the modified attached dispersed optics configuration can be connected to the modified attached lens optics configuration to form the spectral encoding endoscopy configuration(s) which can extends along a particular axis.Type: ApplicationFiled: September 14, 2017Publication date: January 11, 2018Inventors: Milen Shishkov, Guillermo J. Tearney, Brett Eugene Bouma, Dvir Yelin, Nicusor Iftimia
-
Patent number: 9791317Abstract: Exemplary apparatus for method for forming at least one spectral encoding endoscopy configuration. For example, it is possible to modify a spacer configuration and an lens optics configuration to have respective predetermined lengths, and also to modify a dispersive optics configuration to have a further predetermined length. Further, the modified spacer and modified lens optics configurations can be attached to one another to form a combined spacer-lens optics configuration. The modified dispersive optics configuration can be attached to a substrate to form to form a grating substrate configuration. Additionally, the combined spacer-lens optics configuration can be connected to an optical fiber, and the modified attached dispersed optics configuration can be connected to the modified attached lens optics configuration to form the spectral encoding endoscopy configuration(s) which can extends along a particular axis.Type: GrantFiled: December 12, 2016Date of Patent: October 17, 2017Assignee: The General Hospital CorporationInventors: Milen Shishkov, Guillermo J. Tearney, Brett Eugene Bouma, Dvir Yelin, Nicusor Iftimia
-
Patent number: 9763623Abstract: An apparatus, method and software arrangement for imaging a surface of a structure that is in contact with an opaque fluid is provided. The apparatus includes an article of manufacture (e.g., a housing), a fluid delivery arrangement and an imaging arrangement. The housing includes an aperture formed in the article of manufacture. The fluid delivery arrangement is configured to deliver a volume of substantially transparent fluid to the aperture formed in the housing. The imaging arrangement is configured to image the surface of the structure using an imaging modality after the volume of the transparent fluid is delivered to the aperture, wherein the imaging arrangement and/or the article of manufacture is translated along the surface of the structure while imaging the surface of the structure.Type: GrantFiled: November 15, 2010Date of Patent: September 19, 2017Assignee: The General Hospital CorporationInventors: Guillermo J. Tearney, Milen Shishkov, Brett E. Bouma
-
Publication number: 20170238809Abstract: Arrangements, apparatus, systems and systems are provided for obtaining data for at least one portion within at least one luminal or hollow sample. The arrangement, system or apparatus can be (insertable via at least one of a mouth or a nose of a patient. For example, a first optical arrangement can be configured to transceive at least one electromagnetic (e.g., visible) radiation to and from the portion. A second arrangement may be provided at least partially enclosing the first arrangement. Further, a third arrangement can be configured to be actuated so as to position the first arrangement at a predetermined location within the luminal or hollow sample. The first arrangement may be configured to compensate for at least one aberration (e.g., astigmatism) caused by the second arrangement and/or the third arrangement. The second arrangement can include at least one portion which enables a guiding arrangement to be inserted there through.Type: ApplicationFiled: May 8, 2017Publication date: August 24, 2017Inventors: Guillermo J. TEARNEY, MILEN SHISHKOV, BRETT EUGENE BOUMA, BENJAMIN J. VAKOC, NORMAN S. NISHIOKA
-
Publication number: 20170160132Abstract: Exemplary apparatus for method for forming at least one spectral encoding endoscopy configuration. For example, it is possible to modify a spacer configuration and an lens optics configuration to have respective predetermined lengths, and also to modify a dispersive optics configuration to have a further predetermined length. Further, the modified spacer and modified lens optics configurations can be attached to one another to form a combined spacer-lens optics configuration. The modified dispersive optics configuration can be attached to a substrate to form to form a grating substrate configuration. Additionally, the combined spacer-lens optics configuration can be connected to an optical fiber, and the modified attached dispersed optics configuration can be connected to the modified attached lens optics configuration to form the spectral encoding endoscopy configuration(s) which can extends along a particular axis.Type: ApplicationFiled: December 12, 2016Publication date: June 8, 2017Inventors: Milen Shishkov, Guillermo J. Tearney, Brett Eugene Bouma, Dvir Yelin, Nicusor lftimia
-
Publication number: 20170135584Abstract: Exemplary systems, devices, methods, apparatus and computer-accessible media for providing and/or utilizing optical frequency domain imaging (OFDI) and fluorescence of structures and, e.g., multimodality imaging using OFDI techniques and fluorescence imaging techniques are described. For example, an arrangement can provide at least one electro-magnetic radiation to an anatomical structure. Such exemplary arrangement can include at least one optical core and at least one cladding at least partially surrounding the fiber(s). A region between the optical core(s) and the cladding(s) can have an index that is different from indexes of the optical core(s) and the cladding(s). The arrangement can also include at least one apparatus which is configured to transmit the radiation(s) via the optical core(s) and the cladding(s) to the anatomical structure.Type: ApplicationFiled: November 22, 2016Publication date: May 18, 2017Inventors: Guillermo J. Tearney, Brett Eugene Bouma, Hongki Yoo, Milen Shishkov, Joseph Gardecki, Roman Shubochkin, Theodore Morse, Farouc Amin Jaffer
-
Patent number: 9646377Abstract: Arrangements, apparatus, systems and systems are provided for obtaining data for at least one portion within at least one luminal or hollow sample. The arrangement, system or apparatus can be (insertable via at least one of a mouth or a nose of a patient. For example, a first optical arrangement can be configured to transceive at least one electromagnetic (e.g., visible) radiation to and from the portion. A second arrangement may be provided at least partially enclosing the first arrangement. Further, a third arrangement can be configured to be actuated so as to position the first arrangement at a predetermined location within the luminal or hollow sample. The first arrangement may be configured to compensate for at least one aberration (e.g., astigmatism) caused by the second arrangement and/or the third arrangement. The second arrangement can include at least one portion which enables a guiding arrangement to be inserted there through.Type: GrantFiled: April 2, 2014Date of Patent: May 9, 2017Assignee: The General Hospital CorporationInventors: Guillermo J. Tearney, Milen Shishkov, Brett Eugene Bouma, Benjamin J. Vakoc, Norman S. Nishioka
-
Patent number: 9557154Abstract: Exemplary systems, devices, methods, apparatus and computer-accessible media for providing and/or utilizing optical frequency domain imaging (OFDI) and fluorescence of structures and, e.g., multimodality imaging using OFDI techniques and fluorescence imaging techniques are described. For example, an arrangement can provide at least one electro-magnetic radiation to an anatomical structure. Such exemplary arrangement can include at least one optical core and at least one cladding at least partially surrounding the fiber(s). A region between the optical core(s) and the cladding(s) can have an index that is different from indexes of the optical core(s) and the cladding(s). The arrangement can also include at least one apparatus which is configured to transmit the radiation(s) via the optical core(s) and the cladding(s) to the anatomical structure.Type: GrantFiled: May 24, 2011Date of Patent: January 31, 2017Assignees: The General Hospital Corporation, Boston UniversityInventors: Guillermo J. Tearney, Brett Eugene Bouma, Hongki Yoo, Milen Shishkov, Joseph Gardecki, Roman Shubochkin, Theodore Morse, Farouc Amin Jaffer
-
Patent number: 9516997Abstract: Exemplary apparatus for obtaining information for a structure can be provided. For example, the exemplary apparatus can include at least one first optical fiber arrangement which is configured to transceive at least one first electro-magnetic radiation, and can include at least one fiber. The exemplary apparatus can also include at least one second focusing arrangement in optical communication with the optical fiber arrangement. The second arrangement can be configured to focus and provide there through the first electro-magnetic radiation to generate the focused electro-magnetic radiation. Further, the exemplary apparatus can include at least at least one dispersive third arrangement which can receive a particular radiation (e.g., the first electro-magnetic radiation(s) and/or the focused electro-magnetic radiation), and forward a dispersed radiation thereof to at least one section of the structure.Type: GrantFiled: August 22, 2014Date of Patent: December 13, 2016Assignee: The General Hospital CorporationInventors: Milen Shishkov, Guillermo J. Tearney, Brett Eugene Bouma, Dvir Yelin, Nicusor Iftimia
-
Patent number: 9254102Abstract: An apparatus, method and software arrangement for imaging a surface of a structure that is in contact with an opaque fluid is provided. The apparatus includes an article of manufacture (e.g., a housing), a fluid delivery arrangement and an imaging arrangement. The housing includes an aperture formed in the article of manufacture. The fluid delivery arrangement is configured to deliver a volume of substantially transparent fluid to the aperture formed in the housing. The imaging arrangement is configured to image the surface of the structure using an imaging modality after the volume of the transparent fluid is delivered to the aperture, wherein the imaging arrangement and/or the article of manufacture is translated along the surface of the structure while imaging the surface of the structure.Type: GrantFiled: September 6, 2011Date of Patent: February 9, 2016Assignee: The General Hospital CorporationInventors: Guillermo J. Tearney, Milen Shishkov, Brett Eugene Bouma