Patents by Inventor Milene Saavedra

Milene Saavedra has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for Categorizing and Treating Subjects at Risk for Pulmonary Exacerbation and Disease Progression
    Publication number: 20220205987
    Abstract: The present invention is related to novel methods for categorizing and treating a population of subjects that are at risk for increased pulmonary exacerbation and disease progression.
    Type: Application
    Filed: October 8, 2021
    Publication date: June 30, 2022
    Inventor: Milene Saavedra
  • Methods for Categorizing and Treating Subjects at Risk for Pulmonary Exacerbation and Disease Progression
    Publication number: 20200256859
    Abstract: The present invention is related to novel methods for categorizing and treating a population of subjects that are at risk for increased pulmonary exacerbation and disease progression.
    Type: Application
    Filed: December 5, 2019
    Publication date: August 13, 2020
    Inventor: Milene Saavedra
  • Methods for Diagnosing and Treating Subjects for Pulmonary Exacerbation
    Publication number: 20200116736
    Abstract: The present invention is related to novel methods for diagnosing and treating acute pulmonary exacerbation in subjects in need thereof.
    Type: Application
    Filed: August 28, 2019
    Publication date: April 16, 2020
    Inventors: Milene Saavedra, Vijaya Knight
  • Methods for categorizing and treating subjects at risk for pulmonary exacerbation and disease progression
    Patent number: 10539558
    Abstract: The present invention is related to novel methods for for determining pulmonary disease progression severity in a subject having cystic fibrosis by detecting mRNA expression levels of CD64 in a whole blood sample for the subject and calculating a disease risk score, wherein the disease risk score correlates to the risk score for mild, moderate or severe pulmonary disease progression at exacerbation and treating the subject accordingly.
    Type: Grant
    Filed: September 18, 2018
    Date of Patent: January 21, 2020
    Assignee: National Jewish Health
    Inventor: Milene Saavedra
  • Methods for diagnosing and treating subjects for pulmonary exacerbation
    Patent number: 10436799
    Abstract: The present invention is related to novel methods for diagnosing and treating acute pulmonary exacerbation in subjects in need thereof.
    Type: Grant
    Filed: September 30, 2016
    Date of Patent: October 8, 2019
    Assignee: National Jewish Health
    Inventors: Milene Saavedra, Vijaya Knight
  • Methods for Categorizing and Treating Subjects at Risk for Pulmonary Exacerbation and Disease Progression
    Publication number: 20190128878
    Abstract: The present invention is related to novel methods for categorizing and treating a population of subjects that are at risk for increased pulmonary exacerbation and disease progression.
    Type: Application
    Filed: September 18, 2018
    Publication date: May 2, 2019
    Inventor: Milene Saavedra
  • Method for treating pulmonary exacerbation and disease progression in subjects having cystic fibrosis
    Patent number: 10126295
    Abstract: The present invention is related to a method for determining pulmonary disease progression severity in a subject having cystic fibrosis and treating the subject according to the severity. The method comprises obtaining a whole blood sample from the subject; detecting the mRNA expression level of each of the following genes: TLR2, ADAM9, PLXND1, CD163, CD36, CD64, CSPG2, IL32, HPSE, HCA112; determining the severity of the pulmonary disease progression based on the subject's combined mRNA expression level of the genes; and treating the subject.
    Type: Grant
    Filed: March 23, 2015
    Date of Patent: November 13, 2018
    Assignee: National Jewish Health
    Inventor: Milene Saavedra
  • Markers for diagnosis of pulmonary inflammation and methods related thereto
    Patent number: 9624543
    Abstract: The present invention is related to the novel discovery of a number of genes that were identified as systemic markers of pulmonary inflammation. This discovery allows for development of a novel tool for reliable, rapid and efficient assessment of therapeutic responses and enables design of novel therapies targeted against diseases associated with pulmonary inflammation. In one embodiment, the present invention allows quantification of therapeutic response in patients who have a disease associated with pulmonary inflammation. In preferred embodiments, the genes are CD64, ADAM9, CD36, IL32, HPSE, PLXND1, HCA112, CSPG2, TLR2, and CD163.
    Type: Grant
    Filed: July 15, 2015
    Date of Patent: April 18, 2017
    Assignee: National Jewish Health
    Inventors: Milene Saavedra, Jerry Nick
  • Methods for Diagnosing and Treating Subjects for Pulmonary Exacerbation
    Publication number: 20170102395
    Abstract: The present invention is related to novel methods for diagnosing and treating acute pulmonary exacerbation in subjects in need thereof.
    Type: Application
    Filed: September 30, 2016
    Publication date: April 13, 2017
    Inventors: Milene Saavedra, Vijaya Knight
  • MARKERS FOR DIAGNOSIS OF PULMONARY INFLAMMATION AND METHODS RELATED THERETO
    Publication number: 20160068909
    Abstract: The present invention is related to the novel discovery of a number of genes that were identified as systemic markers of pulmonary inflammation. This discovery allows for development of a novel tool for reliable, rapid and efficient assessment of therapeutic responses and enables design of novel therapies targeted against diseases associated with pulmonary inflammation. In one embodiment, the present invention allows quantification of therapeutic response in patients who have a disease associated with pulmonary inflammation.
    Type: Application
    Filed: July 15, 2015
    Publication date: March 10, 2016
    Inventors: Milene Saavedra, Jerry Nick
  • Methods for Categorizing and Treating Subjects at Risk for Pulmonary Exacerbation and Disease Progression
    Publication number: 20150322520
    Abstract: The present invention is related to novel methods for categorizing and treating a population of subjects that are at risk for increased pulmonary exacerbation and disease progression.
    Type: Application
    Filed: March 23, 2015
    Publication date: November 12, 2015
    Inventor: Milene Saavedra
  • MARKERS FOR DIAGNOSIS OF PULMONARY INFLAMMATION AND METHODS RELATED THERETO
    Publication number: 20140005099
    Abstract: The present invention is related to the novel discovery of a number of genes that were identified as systemic markers of pulmonary inflammation. This discovery allows for development of a novel tool for reliable, rapid and efficient assessment of therapeutic responses and enables design of novel therapies targeted against diseases associated with pulmonary inflammation. In one embodiment, the present invention allows quantification of therapeutic response in patients who have a disease associated with pulmonary inflammation. In preferred embodiments, the genes are CD64, ADAM9, CD36, IL32, HPSE, PLXND1, HCA112, CSPG2, TLR2, and CD163.
    Type: Application
    Filed: May 16, 2013
    Publication date: January 2, 2014
    Applicant: National Jewish Health
    Inventors: Milene Saavedra, Jerry Nick
  • Markers for diagnosis of pulmonary inflammation and methods related thereto
    Patent number: 8465923
    Abstract: The present invention is related to the novel discovery of a number of genes that were identified as systemic markers of pulmonary inflammation. This discovery allows for development of a novel tool for reliable, rapid and efficient assessment of therapeutic responses and enables design of novel therapies targeted against diseases associated with pulmonary inflammation. In one embodiment, the present invention allows quantification of therapeutic response in patients who have a disease associated with pulmonary inflammation. In preferred embodiments, the genes are CD64, ADAM9, CD36, IL32, HPSE, PLXND1, HCA 112, CSPG2, TLR2, and CD163.
    Type: Grant
    Filed: December 16, 2011
    Date of Patent: June 18, 2013
    Assignee: National Jewish Health
    Inventors: Milene Saavedra, Jerry Nick
  • MARKERS FOR DIAGNOSIS OF PULMONARY INFLAMMATION AND METHODS RELATED THERETO
    Publication number: 20120149595
    Abstract: The present invention is related to the novel discovery of a number of genes that were identified as systemic markers of pulmonary inflammation. This discovery allows for development of a novel tool for reliable, rapid and efficient assessment of therapeutic responses and enables design of novel therapies targeted against diseases associated with pulmonary inflammation. In one embodiment, the present invention allows quantification of therapeutic response in patients who have a disease associated with pulmonary inflammation. In preferred embodiments, the genes are CD64, ADAM9, CD36, IL32, HPSE, PLXND1, HCA 112, CSPG2, TLR2, and CD163.
    Type: Application
    Filed: December 16, 2011
    Publication date: June 14, 2012
    Applicant: National Jewish Health
    Inventors: Milene Saavedra, Jerry Nick
  • Markers for diagnosis of pulmonary inflammation and methods related thereto
    Patent number: 8101361
    Abstract: The present invention is related to the novel discovery of a number of genes that were identified as systemic markers of pulmonary inflammation. This discovery allows for development of a novel tool for reliable, rapid and efficient assessment of therapeutic responses and enables design of novel therapies targeted against diseases associated with pulmonary inflammation. In one embodiment, the present invention allows quantification of therapeutic response in patients who have a disease associated with pulmonary inflammation. In preferred embodiments, the genes are CD64, ADAM9, CD36, IL32, HPSE, PLXND1, HCA112, CSPG2, TLR2, and CD163.
    Type: Grant
    Filed: March 10, 2009
    Date of Patent: January 24, 2012
    Assignee: National Jewish Health
    Inventors: Milene Saavedra, Jerry Nick
  • Markers for Diagnosis of Pulmonary Inflammation and Methods Related Thereto
    Publication number: 20090233300
    Abstract: The present invention is related to the novel discovery of a number of genes that were identified as systemic markers of pulmonary inflammation. This discovery allows for development of a novel tool for reliable, rapid and efficient assessment of therapeutic responses and enables design of novel therapies targeted against diseases associated with pulmonary inflammation. In one embodiment, the present invention allows quantification of therapeutic response in patients who have a disease associated with pulmonary inflammation. In preferred embodiments, the genes are CD64, ADAM9, CD36, IL32, HPSE, PLXND1, HCA112, CSPG2, TLR2, and CD163.
    Type: Application
    Filed: March 10, 2009
    Publication date: September 17, 2009
    Inventors: Milene Saavedra, Jerry Nick