Patents by Inventor Miles D. Alexander
Miles D. Alexander has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20160302924Abstract: Systems for partitioning a ventricle of a heart include a partitioning device or implant, and an applicator for inserting, repositioning and/or removing the partitioning device. The implant may support the ventricle wall and may reduce the volume of the ventricle. The delivery system for delivering and deploying a partitioning device into a ventricle may include a catheter having a distal coupling element for coupling to a partitioning device in a collapsed configuration; the catheter may also have an expansion member for applying force to the partitioning device to fully expand it into a deployed configuration and to secure or seal it against the ventricle wall.Type: ApplicationFiled: April 19, 2016Publication date: October 20, 2016Inventors: Michael P. BOUTILLETTE, James R. KERMODE, Miles D. ALEXANDER, Alexander KHAIRKHAHAN, Serjan D. NIKOLIC
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Publication number: 20160262892Abstract: Devices and systems including implants (which may be removable) and methods of using them for reducing ventricular volume. The implants described herein are cardiac implants that may be inserted into a patient's heart, particularly the left ventricle. The implant may support the heart wall, or may be secured to the heart wall. The implants are typically ventricular partitioning device for partitioning the ventricle into productive and non-productive regions in order to reduce the ventricular volume.Type: ApplicationFiled: May 19, 2016Publication date: September 15, 2016Inventors: James R. KERMODE, Miles D. ALEXANDER, Michael P. BOUTILLETTE, Matthew T. DAVILA, Irene Bing Bie TAN
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Patent number: 9364327Abstract: Devices and systems including implants (which may be removable) and methods of using them for reducing ventricular volume. The implants described herein are cardiac implants that may be inserted into a patient's heart, particularly the left ventricle. The implant may support the heart wall, or may be secured to the heart wall. The implants are typically ventricular partitioning device for partitioning the ventricle into productive and non-productive regions in order to reduce the ventricular volume.Type: GrantFiled: March 20, 2015Date of Patent: June 14, 2016Assignee: CardioKinetix, Inc.Inventors: James R. Kermode, Miles D. Alexander, Michael P. Boutillette, Matthew T. Davila, Irene Bing Bie Tan
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Patent number: 9332993Abstract: Described herein are devices, systems and methods for delivering an endocardial device. The systems for delivering the device transvascularly may generally include an elongate guide catheter having a proximal end and a distal end; a conical dilator at the distal end of the elongate guide catheter, the conical dilator being removable to enable delivery of the ventricular portioning device; a delivery catheter having a proximal and distal end; an expansion member near the distal end of the delivery catheter and configured to expand a plurality of struts of the partitioning device; and a coupling element configured to deployably secure to a hub of the partitioning device. The systems for delivering the device transapically may generally include an elongate access sheath; an elongate delivery catheter; an expansion member; and a coupling element proximal to the expansion member and configured to deployably secure to a hub of the partitioning device.Type: GrantFiled: March 14, 2013Date of Patent: May 10, 2016Assignee: CardioKinetix, Inc.Inventors: James R. Kermode, Miles D. Alexander, Matthew T. Davila
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Patent number: 9332992Abstract: Described herein are systems and methods for securing a polymeric sheet to rib components of a frame structure, wherein the rib components are jointed at a hub to form an expandable and collapsible implant. In general, the method may include the steps of decreasing a diameter of the frame structure; placing the frame structure into an assembly fixture, wherein the assembly fixture is configured to hold the frame structure in a loaded configuration with a decreased diameter; placing a polymeric sheet into the assembly fixture; and heating the assembly under pressure to fuse the sheet to the frame structure. In general, a fixture may include a first and second platen having a shaping portion and a rim portion positioned around the periphery of the platen, wherein the shaping portions are configured to hold the rib components of the frame structure in a loaded configuration with a decreased diameter.Type: GrantFiled: March 14, 2013Date of Patent: May 10, 2016Assignee: CardioKinetix, Inc.Inventor: Miles D. Alexander
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Publication number: 20150265405Abstract: Systems for partitioning a ventricle of a heart include a partitioning device or implant, and an applicator for inserting, repositioning and/or removing the partitioning device. The implant may support the ventricle wall and may reduce the volume of the ventricle. The delivery system for delivering and deploying a partitioning device into a ventricle may include a catheter having a distal coupling element for coupling to a partitioning device in a collapsed configuration; the catheter may also have an expansion member for applying force to the partitioning device to fully expand it into a deployed configuration and to secure or seal it against the ventricle wall.Type: ApplicationFiled: June 4, 2015Publication date: September 24, 2015Inventors: Michael P. BOUTILLETTE, James R. KERMODE, Miles D. ALEXANDER, Alexander KHAIRKHAHAN, Serjan D. NIKOLIC
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Patent number: 9078660Abstract: Systems for partitioning a ventricle of a heart include a partitioning device or implant, and an applicator for inserting, repositioning and/or removing the partitioning device. The implant may support the ventricle wall and may reduce the volume of the ventricle. The delivery system for delivering and deploying a partitioning device into a ventricle may include a catheter having a distal coupling element for coupling to a partitioning device in a collapsed configuration; the catheter may also have an expansion member for applying force to the partitioning device to fully expand it into a deployed configuration and to secure or seal it against the ventricle wall.Type: GrantFiled: September 29, 2010Date of Patent: July 14, 2015Assignee: CardioKinetix, Inc.Inventors: Michael P. Boutillette, James R. Kermode, Miles D. Alexander, Alexander Khairkhahan, Serjan D. Nikolic
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Publication number: 20150182338Abstract: Devices and systems including implants (which may be removable) and methods of using them for reducing ventricular volume. The implants described herein are cardiac implants that may be inserted into a patient's heart, particularly the left ventricle. The implant may support the heart wall, or may be secured to the heart wall. The implants are typically ventricular partitioning device for partitioning the ventricle into productive and non-productive regions in order to reduce the ventricular volume.Type: ApplicationFiled: March 20, 2015Publication date: July 2, 2015Inventors: James R. KERMODE, Miles D. ALEXANDER, Michael P. BOUTILLETTE, Matthew T. DAVILA, Irene Bing Bie TAN
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Patent number: 9039597Abstract: Devices and systems including implants (which may be removable) and methods of using them for reducing ventricular volume. The implants described herein are cardiac implants that may be inserted into a patient's heart, particularly the left ventricle. The implant may support the heart wall, or may be secured to the heart wall. The implants are typically ventricular partitioning device for partitioning the ventricle into productive and non-productive regions in order to reduce the ventricular volume.Type: GrantFiled: June 13, 2014Date of Patent: May 26, 2015Assignee: CardioKinetix, Inc.Inventors: James R. Kermode, Miles D. Alexander, Michael P. Boutillette, Matthew T. Davila, Irene Bing Bie Tan
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Publication number: 20140296624Abstract: Devices and systems including implants (which may be removable) and methods of using them for reducing ventricular volume. The implants described herein are cardiac implants that may be inserted into a patient's heart, particularly the left ventricle. The implant may support the heart wall, or may be secured to the heart wall. The implants are typically ventricular partitioning device for partitioning the ventricle into productive and non-productive regions in order to reduce the ventricular volume.Type: ApplicationFiled: June 13, 2014Publication date: October 2, 2014Inventors: James R. KERMODE, Miles D. ALEXANDER, Michael P. BOUTILLETTE, Matthew T. DAVILA, Irene Bing Bie TAN
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Patent number: 8790242Abstract: Devices and systems including implants (which may be removable) and methods of using them for reducing ventricular volume. The implants described herein are cardiac implants that may be inserted into a patient's heart, particularly the left ventricle. The implant may support the heart wall, or may be secured to the heart wall. The implants are typically ventricular partitioning device for partitioning the ventricle into productive and non-productive regions in order to reduce the ventricular volume.Type: GrantFiled: October 26, 2010Date of Patent: July 29, 2014Assignee: CardioKinetix, Inc.Inventors: James R. Kermode, Miles D. Alexander, Michael P. Boutillette, Matthew T. Davila, Irene Bing Bie Tan
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Publication number: 20140179993Abstract: A system for improving cardiac function is provided. A foldable and expandable frame having at least one anchoring formation is attached to an elongate manipulator and placed in a catheter tube while folded. The tube is inserted into a left ventricle of a heart where the frame is ejected from the tube and expands in the left ventricle. Movements of the elongate manipulator cause the anchor to penetrate the heart muscle and the elongate manipulator to release the frame. The installed frame minimizes the effects of an akinetic portion of the heart forming an aneurysmic bulge. Devices and methods are described herein which are directed to the treatment of a patient's heart having, or one which is susceptible to heart failure, to improve diastolic function.Type: ApplicationFiled: February 25, 2014Publication date: June 26, 2014Inventors: Miles D. ALEXANDER, Matthew L. PEASE, Barry L TEMPLIN, Serjan D. NIKOLIC
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Publication number: 20130274595Abstract: Described herein are devices, systems and methods for delivering an endocardial device. The systems for delivering the device transvascularly may generally include an elongate guide catheter having a proximal end and a distal end; a conical dilator at the distal end of the elongate guide catheter, the conical dilator being removable to enable delivery of the ventricular portioning device; a delivery catheter having a proximal and distal end; an expansion member near the distal end of the delivery catheter and configured to expand a plurality of struts of the partitioning device; and a coupling element configured to deployably secure to a hub of the partitioning device. The systems for delivering the device transapically may generally include an elongate access sheath; an elongate delivery catheter; an expansion member; and a coupling element proximal to the expansion member and configured to deployably secure to a hub of the partitioning device.Type: ApplicationFiled: March 14, 2013Publication date: October 17, 2013Inventors: James R. KERMODE, Miles D. Alexander, Matthew T. Davila
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Publication number: 20130270735Abstract: Described herein are systems and methods for securing a polymeric sheet to rib components of a frame structure, wherein the rib components are jointed at a hub to form an expandable and collapsible implant. In general, the method may include the steps of decreasing a diameter of the frame structure; placing the frame structure into an assembly fixture, wherein the assembly fixture is configured to hold the frame structure in a loaded configuration with a decreased diameter; placing a polymeric sheet into the assembly fixture; and heating the assembly under pressure to fuse the sheet to the frame structure. In general, a fixture may include a first and second platen having a shaping portion and a rim portion positioned around the periphery of the platen, wherein the shaping portions are configured to hold the rib components of the frame structure in a loaded configuration with a decreased diameter.Type: ApplicationFiled: March 14, 2013Publication date: October 17, 2013Inventor: Miles D. ALEXANDER
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Publication number: 20110098525Abstract: Devices and systems including implants (which may be removable) and methods of using them for reducing ventricular volume. The implants described herein are cardiac implants that may be inserted into a patient's heart, particularly the left ventricle. The implant may support the heart wall, or may be secured to the heart wall. The implants are typically ventricular partitioning device for partitioning the ventricle into productive and non-productive regions in order to reduce the ventricular volume.Type: ApplicationFiled: October 26, 2010Publication date: April 28, 2011Inventors: James R. Kermode, Miles D. Alexander, Michael P. Boutillette, Matthew T. Davila, Irene Bing Bie Tan
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Publication number: 20110087066Abstract: Described herein are systems for partitioning a ventricle of a heart. The systems may include a partitioning device or implant, and an applicator for inserting, repositioning and/or removing the partitioning device. The implant may support the ventricle wall and may reduce the volume of the ventricle. In particular, described herein are systems for delivering and deploying a partitioning device into a ventricle. The delivery system may include a catheter having a distal coupling element for coupling to a partitioning device in a collapsed configuration; the catheter may also have an expansion member for applying force to the partitioning device to fully expand it into a deployed configuration and to secure or seal it against the ventricle wall.Type: ApplicationFiled: September 29, 2010Publication date: April 14, 2011Inventors: Michael P. Boutillette, James R. Kermode, Miles D. Alexander, Alexander Khairkhahan, Serjan D. Nikolic
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Publication number: 20100274227Abstract: Described herein are handle covers for use with one or more delivery catheters that may be used to deliver and/or remove an expandable cardiac implant. A handle cover may be formed from two interlocking pieces, and may include a control adapter that may be used to control release and/or attachment of an expandable implant. The control adapter may be configured to interact with an implant release control on the delivery catheter. The control adapter may also be lockable to prevent unintended activation of the implant release control. The handle cover may be reusable or disposable (e.g., single-use). In general, the implant control may be shaped so that hit may be held by a doctor, technician or other user, and may facilitate access to various components of the delivery catheter, including one or more ports (e.g., vacuum/inflation ports, etc.).Type: ApplicationFiled: February 10, 2010Publication date: October 28, 2010Inventors: Alexander Khairkhahan, Miles D. Alexander
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Publication number: 20090318813Abstract: An applicator for delivering ultrasound energy that comprises an ultrasound transducer adapted and configured to be electrically coupled to an ultrasound generator. A housing carries the ultrasound transducer for use. An element supports the transducer within the housing. The element includes an elastic material having a hardness of about 30 Shore A to about 100 Shore A.Type: ApplicationFiled: August 26, 2009Publication date: December 24, 2009Inventors: Todd A. Thompson, Veijo T. Suorsa, Michael J. Horzewski, Miles D. Alexander
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Publication number: 20030069526Abstract: An applicator for delivering ultrasound energy that comprises an ultrasound transducer adapted and configured to be electrically coupled to an ultrasound generator. A housing carries the ultrasound transducer for use. An element supports the transducer within the housing. The element includes an elastic material having a hardness of about 30 Shore A to about 100 Shore A.Type: ApplicationFiled: July 24, 2002Publication date: April 10, 2003Applicant: TIMI 3 SYSTEMS, INC.Inventors: Todd A. Thompson, Veijo T. Suorsa, Michael J. Horzewski, Miles D. Alexander