Patents by Inventor Miles Libbey

Miles Libbey has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Formulations for administering calcitonin and processes for preparing the same
    Patent number: 6531112
    Abstract: The present invention provides a non-invasive method for administering polypeptides across epithelial membranes. The formulations in the present invention comprise solid polypeptide particles mixed with a permeation enhancer and excipients which are dispersed in a media for oral or intranasal administration. Also provided in the present invention is a process to prepare the formulations.
    Type: Grant
    Filed: May 14, 2001
    Date of Patent: March 11, 2003
    Assignee: DelRx Pharmaceutical Corporation
    Inventors: Randall E. McCoy, Robert O. Williams, III, Miles A. Libbey, III
  • Formulation and system for intra-oral delivery of pharmaceutical agents
    Patent number: 6495120
    Abstract: A stable formulation is disclosed that enables the effective intra-oral delivery to a patient of a pharmaceutical agent. The formulation comprises the pharmaceutical agent mixed with an orally-acceptable oral-absorption enhancer in an orally-acceptable carrier-solvent, wherein the oral-absorption enhancer is adapted to modify the surface membrane such that absorption through the surface membrane is initiated or increased. The oral-absorption enhancer may comprise hydroxypropyl-beta-cyclodextrin and surfactants including benzalkonium chloride, benzethonium chloride, polysorbate 80, sodium lauryl sulfate, Brij surfactants, Tween and Pluronic surfactants. Also disclosed is a system for delivering the formulation including a mechanism for dispensing predetermined doses of the inventive formulation intra-orally as with an aerosol or spray pump or propellant device.
    Type: Grant
    Filed: August 30, 2001
    Date of Patent: December 17, 2002
    Inventors: Randall McCoy, Robert O. Williams, III, Miles A. Libbey, III
  • Formulations for administering calcitonin and processes for preparing the same
    Publication number: 20020132757
    Abstract: The present invention provides a non-invasive method for administering polypeptides across epithelial membranes. The formulations in the present invention comprise solid polypeptide particles mixed with a permeation enhancer and excipients which are dispersed in a media for oral or intranasal administration. Also provided in the present invention is a process to prepare the formulations.
    Type: Application
    Filed: May 14, 2001
    Publication date: September 19, 2002
    Inventors: Randall E. McCoy, Robert O. Williams, Miles A. Libbey
  • Formulation and system for intra-oral delivery of pharmaceutical agents
    Publication number: 20020055496
    Abstract: A stable formulation is disclosed that enables the effective intra-oral delivery to a patient of a pharmaceutical agent. The formulation comprises the pharmaceutical agent mixed with an orally-acceptable oral-absorption enhancer in an orally-acceptable carrier-solvent, wherein the oral-absorption enhancer is adapted to modify the surface membrane such that absorption through the surface membrane is initiated or increased. The oral-absorption enhancer may comprise hydroxypropyl-beta-cyclodextrin and surfactants including benzalkonium chloride, benzethonium chloride, polysorbate 80, sodium lauryl sulfate, Brij surfactants, Tween and Pluronic surfactants. Also disclosed is a system for delivering the formulation including a mechanism for dispensing predetermined doses of the inventive formulation intra-orally as with an aerosol or spray pump or propellant device.
    Type: Application
    Filed: August 30, 2001
    Publication date: May 9, 2002
    Inventors: Randall McCoy, Robert O. Williams, Miles A. Libbey III