Patents by Inventor Miles P. Smith

Miles P. Smith has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • IMAGING AGENTS FOR DIAGNOSIS OF PARKINSON'S DISEASE
    Publication number: 20080312446
    Abstract: Generally, the present invention is directed to central nervous system dopamine transporter-imaging agents and methods of use thereof. In certain embodiments, the present invention relates to radiolabeled piperidine derivatives for use as imaging agents in the diagnosis of Parkinson's disease. Another aspect of the present invention relates to piperidine monoamine transporter ligands, comprising a functional group capable of chelating a radionuclide, e.g., technetium, and methods of use thereof.
    Type: Application
    Filed: October 31, 2007
    Publication date: December 18, 2008
    Inventors: John W. Babich, Miles P. Smith
  • Imaging agents for diagnosis of Parkinson's disease
    Patent number: 7317103
    Abstract: Generally, the present invention is directed to central nervous system dopamine transporter-imaging agents and methods of use thereof. In certain embodiments, the present invention relates to radiolabeled piperidine derivatives for use as imaging agents in the diagnosis of Parkinson's disease. Another aspect of the present invention relates to piperidine monoamine transporter ligands, comprising a functional group capable of chelating a radionuclide, e.g., technetium, and methods of use thereof.
    Type: Grant
    Filed: January 13, 2004
    Date of Patent: January 8, 2008
    Assignee: Molecular Insight Pharmaceuticals, Inc.
    Inventors: John W. Babich, Miles P. Smith
  • Imaging agents for diagnosis of Parkinson's disease
    Patent number: 6677454
    Abstract: Generally, the present invention is directed to central nervous system dopamine transporter-imaging agents and methods of use thereof. In certain embodiments, the present invention relates to radiolabeled piperidine derivatives for use as imaging agents in the diagnosis of Parkinson's disease. Another aspect of the present invention relates to piperidine monoamine transporter ligands, comprising a functional group capable of chelating a radionuclide, e.g., technetium, and methods of use thereof.
    Type: Grant
    Filed: January 28, 2003
    Date of Patent: January 13, 2004
    Assignee: Biostream Therapeutics, Inc.
    Inventors: John W. Babich, Miles P. Smith
  • Imaging agents for diagnosis of parkinson's disease
    Publication number: 20030208078
    Abstract: Generally, the present invention is directed to central nervous system dopamine transporter-imaging agents and methods of use thereof. In certain embodiments, the present invention relates to radiolabeled piperidine derivatives for use as imaging agents in the diagnosis of Parkinson's disease. Another aspect of the present invention relates to piperidine monoamine transporter ligands, comprising a functional group capable of chelating a radionuclide, e.g., technetium, and methods of use thereof.
    Type: Application
    Filed: January 28, 2003
    Publication date: November 6, 2003
    Inventors: John W. Babich, Miles P. Smith
  • Imagining agents for diagnosis of Parkinson's disease
    Patent number: 6515131
    Abstract: Generally, the present invention is directed to central nervous system dopamine transporter-imaging agents and methods of use thereof. In certain embodiments, the present invention relates to radiolabeled piperidine derivatives for use as imaging agents in the diagnosis of Parkinson's disease. Another aspect of the present invention relates to piperidine monoamine transporter ligands, comprising a functional group capable of chelating a radionuclide, e.g., technetium, and methods of use thereof.
    Type: Grant
    Filed: February 22, 2001
    Date of Patent: February 4, 2003
    Assignee: Biostream Therapeutics, Inc.
    Inventors: John W. Babich, Miles P. Smith
  • N-alkylpiperdine analogs and uses thereof in treating addictions
    Publication number: 20020025967
    Abstract: One aspect of the present invention relates to alkylpiperdine compounds and pharmaceutical compositions thereof. A second aspect of the present invention relates to the use of alkylpiperdine compounds and pharmaceutical compositions thereof as promoters of 5-HT2A antagonistic activity. A third aspect of the invention relates to methods of treating addiction using a compound of the invention or a pharmaceutical compositions thereof.
    Type: Application
    Filed: December 18, 2000
    Publication date: February 28, 2002
    Inventor: Miles P. Smith
  • Imaging agents for diagnosis of Parkinson's disease
    Publication number: 20010044543
    Abstract: Generally, the present invention is directed to central nervous system dopamine transporter-imaging agents and methods of use thereof. In certain embodiments, the present invention relates to radiolabeled piperidine derivatives for use as imaging agents in the diagnosis of Parkinson's disease. Another aspect of the present invention relates to piperidine monoamine transporter ligands, comprising a functional group capable of chelating a radionuclide, e.g., technetium, and methods of use thereof.
    Type: Application
    Filed: February 22, 2001
    Publication date: November 22, 2001
    Inventors: John W. Babich, Miles P. Smith
  • Bi- and tri-cyclic aza compounds and their uses
    Patent number: 6150376
    Abstract: The present invention provides tropane-derived monoamine neurotransmitter re-uptake inhibitors which predictably exhibit selectivity for either the serotonin or dopamine transporter, pharmaceutical compositions thereof and methods for their use. The serotonin-selective re-uptake inhibitors are particularly useful for treating neurological disorders associated with the serotonergic neural system of the brain, such as depression, with significantly reduced side-effects. The dopamine-selective re-uptake inhibitors are particularly useful for treating disorders associated with dopamine re-uptake and/or acetylcholine release.
    Type: Grant
    Filed: August 5, 1998
    Date of Patent: November 21, 2000
    Assignee: Georgetown University
    Inventors: Alan P. Kozikowski, Miles P. Smith