Patents by Inventor Milo Malanga

Milo Malanga has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CYCLODEXTRIN DIMERS AND USES THEREOF
    Publication number: 20240043661
    Abstract: CD dimers, CD compositions, and uses thereof are disclosed herein. CD dimers, and compositions thereof, that may be useful for various purposes including the targeting of 7KC. The design and testing of CD dimers are described herein. Exemplary CD dimers include heterodimers, homodimers, or asymmetric dimer.
    Type: Application
    Filed: July 7, 2021
    Publication date: February 8, 2024
    Inventors: Matthew S. O'Connor, Maria de los Angeles Estiarte-Martinez, Amelia M. Anderson, Daniel M. Clemens, Christine A.T.M.B. Tom, Milo Malanga, Michael Kope, Keivan Sadrerafi
  • Cyclodextrin dimers, compositions thereof, and uses thereof
    Patent number: 11279774
    Abstract: A new class of synthetic cyclodextrin dimers is described. Exemplary cyclodextrin dimers can treat atherosclerotic plaques by targeting various forms cholesterol both intracellularly and extracellularly. Also provided are methods of depleting atherosclerotic plaques of cholesterol, cholesterol esters, 7-ketocholesterol and 7-ketocholesterol esters by treatment with such cyclodextrins. Further described are subclasses of dimers that have high specificity for 7-ketocholesterol.
    Type: Grant
    Filed: January 3, 2020
    Date of Patent: March 22, 2022
    Assignee: UNDERDOG PHARMACEUTICALS, INC.
    Inventors: Matthew S. O'Connor, Milo Malanga, Michael Kope, Christina A. T. M. B. Tom, Amelia M. Anderson
  • CYCLODEXTRIN DIMERS, COMPOSITIONS THEREOF, AND USES THEREOF
    Publication number: 20220056158
    Abstract: A new class of synthetic cyclodextrin dimers is described. Exemplary cyclodextrin dimers can treat atherosclerotic plaques by targeting various forms cholesterol both intracellularly and extracellularly. Also provided are methods of depleting atherosclerotic plaques of cholesterol, cholesterol esters, 7-ketocholesterol and 7-ketocholesterol esters by treatment with such cyclodextrins. Further described are subclasses of dimers that have high specificity for 7-ketocholesterol.
    Type: Application
    Filed: August 30, 2021
    Publication date: February 24, 2022
    Inventors: Matthew S. O'Connor, Milo Malanga, Michael Kope, Christina A.T.M.B. Tom, Amelia M. Anderson
  • CYCLODEXTRIN DIMERS AND USES THEREOF
    Publication number: 20210403607
    Abstract: CD dimers, CD compositions, and uses thereof are disclosed herein.
    Type: Application
    Filed: July 7, 2021
    Publication date: December 30, 2021
    Inventors: Matthew S. O'Connor, Maria de los Angeles Estiarte-Martinez, Amelia M. Anderson, Daniel M. Clemens, Christina A.T.M.B. Tom, Milo Malanga, Michael Kope, Keivan Sadrerafi
  • CYCLODEXTRIN DIMERS, COMPOSITIONS THEREOF, AND USES THEREOF
    Publication number: 20200216576
    Abstract: A new class of synthetic cyclodextrin dimers is described. Exemplary cyclodextrin dimers can treat atherosclerotic plaques by targeting various forms cholesterol both intracellularly and extracellularly. Also provided are methods of depleting atherosclerotic plaques of cholesterol, cholesterol esters, 7-ketocholesterol and 7-ketocholesterol esters by treatment with such cyclodextrins. Further described are subclasses of dimers that have high specificity for 7-ketocholesterol.
    Type: Application
    Filed: January 3, 2020
    Publication date: July 9, 2020
    Inventors: Matthew S. O'Connor, Milo Malanga, Michael Kope, Christina A.T.M.B. Tom, Amelia M. Anderson
  • Organic-inorganic hybrid solid having a modified outer surface
    Patent number: 10159738
    Abstract: The present invention concerns metal-organic hybrid solids having a modified outer surface. These solids can be used, for example, for the storage and vectoring of molecules of interest such as pharmaceutically active ingredients, compounds of interest in cosmetics and markers, for example contrast agents. These solids have good results in terms of active drug loading capacities, biocompatibility, stability and controlling the release of the active ingredients encapsulated.
    Type: Grant
    Filed: May 30, 2013
    Date of Patent: December 25, 2018
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE-CNRS, UNIVERSITE DE VERSAILLES-SAINT QUENTIN EN YVELINES, UNIVERSITE PARIS-SUD
    Inventors: Ruxandra Gref, Valentina Agostoni, Samia Daoud-Mahammed, Violeta Rodriguez-Ruiz, Milo Malanga, Laszlo Jicsinszky, Patricia Horcajada-Cortes, Christian Serre
  • ORGANIC-INORGANIC HYBRID SOLID HAVING A MODIFIED OUTER SURFACE
    Publication number: 20150150981
    Abstract: The present invention concerns metal-organic hybrid solids having a modified outer surface. These solids can be used, for example, for the storage and vectoring of molecules of interest such as pharmaceutically active ingredients, compounds of interest in cosmetics and markers, for example contrast agents. These solids have good results in terms of active drug loading capacities, biocompatibility, stability and controlling the release of the active ingredients encapsulated.
    Type: Application
    Filed: May 30, 2013
    Publication date: June 4, 2015
    Inventors: Ruxandra Gref, Valentina Agostoni, Samia Daoud-Mahammed, Violeta Rodriguez-Ruiz, Milo Malanga, Laszlo Jicsinszky, Patricia Horcajada-Cortes, Christian Serre