Patents by Inventor Milton Datta

Milton Datta has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method and compositions for inhibiting tumorigenesis
    Publication number: 20120083419
    Abstract: The present invention relates to compounds, small interfering RNAs and compositions and methods of inhibiting tumorigenesis and methods of inhibiting tumor cell growth and proliferation using agents that inhibit the hedgehog and Gli signaling pathway, including agents that inhibit GLI synthesis and/or function. The present invention also relates to particular biomarkers that can be used in the diagnosis and prognosis of prostate cancer. Methods of treating cancer, including prostate cancer are also provided using small organic compounds, siRNAs and blocking antibodies that inhibit or block the SHH/GLI pathway.
    Type: Application
    Filed: November 7, 2008
    Publication date: April 5, 2012
    Inventors: Ariel Ruiz i Altaba, Sumana Datta, Milton Datta
  • Detection, evaluation and treatment for advanced prostate cancer
    Publication number: 20060051819
    Abstract: The present invention includes novel compositions, methods and systems for detecting, evaluating and inhibiting the proliferation of prostate cancer cells by detecting and inhibiting the expression and activity of the proteoglycan Perlecan.
    Type: Application
    Filed: June 17, 2005
    Publication date: March 9, 2006
    Applicant: The Texas A&M University System
    Inventors: Milton Datta, Sumana Datta, Ariel Altaba
  • Method and compositions for inhibiting tumorigenesis
    Publication number: 20050130922
    Abstract: The present invention relates to compounds, small interfering RNAs and compositions and methods of inhibiting tumorigenesis and methods of inhibiting tumor cell growth and proliferation using agents that inhibit the hedgehog and Gli signaling pathway, including agents that inhibit GLI synthesis and/or function. The present invention also relates to particular biomarkers that can be used in the diagnosis and prognosis of prostate cancer. Methods of treating cancer, including prostate cancer are also provided using small organic compounds, siRNAs and blocking antibodies that inhibit or block the SHH/GLI pathway.
    Type: Application
    Filed: August 29, 2004
    Publication date: June 16, 2005
    Inventors: Ariel Altaba, Suma Datta, Milton Datta