Patents by Inventor Milton Lethan Pressler

Milton Lethan Pressler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ACE INHIBITOR-VASOPRESSIN ANTAGONIST COMBINATIONS
    Publication number: 20090239844
    Abstract: Combinations of ACE inhibitors and vasopressin antagonists are useful to slow and reverse the process of ventricular dilation, and CHF in mammals.
    Type: Application
    Filed: May 12, 2009
    Publication date: September 24, 2009
    Inventor: Milton Lethan PRESSLER
  • Treatment of congestive heart failure
    Patent number: 7192951
    Abstract: Combinations of diuretics and vasopressin antagonists are useful to slow and reverse the symptoms and process of congestive heart failure, to increase the excretion of water in the urine, and to decrease the excretion of sodium and potassium ions in urine. Preferred vasopressin antagonists have the formula wherein R and R5 are hydrogen or lower alkyl; R1, R2, and R3 are hydrogen, halo, alkyl, alkoxy, and amino; and R4 is hydrogen or phenyl, and a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: June 16, 2005
    Date of Patent: March 20, 2007
    Assignee: Astellas Pharma Inc.
    Inventors: Rebecca Guggemos Bakker-Arkema, Milton Lethan Pressler
  • Treatment of congestive heart failure
    Publication number: 20040176354
    Abstract: Combinations of diuretics and vasopressin antagonists are useful to slow and reverse the symptoms and process of congestive heart failure, to increase the excretion of water in the urine, and to decrease the excretion of sodium and potassium ions in urine.
    Type: Application
    Filed: March 12, 2004
    Publication date: September 9, 2004
    Inventors: Rebecca Guggemos Bakker-Arkema, Milton Lethan Pressler
  • Treatment of pulmonary hypertension
    Patent number: 6740648
    Abstract: Disclosed is a method for treating pulmonary hypertension using a vasopressin antagonist.
    Type: Grant
    Filed: October 3, 2001
    Date of Patent: May 25, 2004
    Assignee: Warner-Lambert Company
    Inventors: Maha Ghazzi, Milton Lethan Pressler
  • Method for treating postoperative ileus
    Patent number: 6645959
    Abstract: This invention is a method for preventing or treating postoperative ileus comprising administering a vasopressin antagonist such as a compound of Formula (1), where R1, R2, and R3 include hydrogen, halo, alkyl, and alkoxy; R and R5 are hydrogen or alkyl; R4 is hydrogen, phenyl, or substituted phenyl, and pharmaceutically acceptable salts thereof.
    Type: Grant
    Filed: April 19, 2002
    Date of Patent: November 11, 2003
    Assignee: Warner-Lambert Company
    Inventors: Rebecca Guggemos Bakker-Arkema, Milton Lethan Pressler
  • Ace inhibitor-vasopressin antagonist combinations
    Publication number: 20030103983
    Abstract: Combinations of ACE inhibitors and vasopressin antagonists are useful to slow and reverse the process of ventricular dilation, and CHF in mammals.
    Type: Application
    Filed: May 9, 2002
    Publication date: June 5, 2003
    Inventor: Milton Lethan Pressler
  • Treatment of congestive heart failure
    Publication number: 20030008860
    Abstract: Combinations of diuretics and vasopressin antagonists are useful to slow and reverse the symptoms and process of congestive heart failure, to increase the excretion of water in the urine, and to decrease the excretion of sodium and potassium ions in urine.
    Type: Application
    Filed: May 9, 2002
    Publication date: January 9, 2003
    Inventors: Rebecca Guggemos Bakker-Arkema, Milton Lethan Pressler
  • Treatment of pulmonary hypertension
    Publication number: 20020128259
    Abstract: Disclosed is a method for treating pulmonary hypertension using a vasopressin antagonist.
    Type: Application
    Filed: October 3, 2001
    Publication date: September 12, 2002
    Inventors: Maha Ghazzi, Milton Lethan Pressler
  • Method for treating chronic obstructive pulmonary disease
    Publication number: 20020115661
    Abstract: Chronic obstructive pulmonary disease is treated with a selective ETA receptor antagonist such as 4-(7-ethyl-1,3-benxodioxol-5-yl)-2-[2-trifluoromethyl) phenyl]-2H-1,2-benzothiazine-3-carboxylic acid 1,1-dioxide or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: September 7, 2001
    Publication date: August 22, 2002
    Inventors: Laurence Harvey Keller, Milton Lethan Pressler
  • ACE inhibitor-MMP inhibitor combinations
    Patent number: 6133304
    Abstract: The present invention relates to compositions comprising a compound which inhibits the actions of angiotensin-converting enzyme and a compound which inhibits the actions of matrix metalloproteinase enzymes and the use of such compositions for treating ventricular dilation, heart failure and cardiovascular fibrotic pathologies.
    Type: Grant
    Filed: February 7, 2000
    Date of Patent: October 17, 2000
    Assignee: Warner-Lambert Company
    Inventors: Joseph Thomas Peterson, Jr., Milton Lethan Pressler
  • Method for treating and preventing heart failure and ventricular dilatation
    Patent number: 5948780
    Abstract: Matrix metalloproteinase inhibitors are useful for preventing and treating heart failure, and ventricular dilatation in mammals.
    Type: Grant
    Filed: December 8, 1997
    Date of Patent: September 7, 1999
    Assignee: Warner-Lambert Company
    Inventors: Joseph Thomas Peterson, Jr., Milton Lethan Pressler