Abstract: A device and method for determining the identity and concentration of constituent compounds of a test specimen. The device and method are based upon the polarization effect that a specimen will have when subjected to randomly polarized light. This polarization effect will cause the intensity of light wither reflecting from or passing through the test specimen at one angle of polarization to be different then the intensity of light exiting the specimen at a second angle of polarization at a specific wavelength. The intensity of light either reflecting from or exiting the test specimen various planes of polarization is accurately measured by irradiating the specimen with randomly polarized light and then polarizing the light reflected from or passing through the specimen in different planes of polarization angles and measuring the intensity of light in each of these polarization planes at one or more wavelengths of light.

Abstract: Methods and devices for determining the identity and concentration of constituent compounds within a test specimen. The methods are based on the principle that a specific compound in a specific concentration will modify a pattern of incident polychromatic light in a manner that is recognizable. The system includes a polychromatic light source directed first through an incident light pattern generator and then through the test specimen. Reflected and transmitted light components then pass through a pattern recognition gating device that selects portions of the light for analysis by an array of detectors. The methods include producing a modulated pattern of incident light specific for a particular compound of interest and selectively analyzing the reflected or transmitted light according to known patterns for that compound in specific concentrations.

Abstract: Finely divided drug particles are coated with a lipid or bioadhesive polymer to form microspheres having a particle size of about 550 micrometers or less, and coated with two or more enteric coatings, at least one of which is water insoluble, to form microcapsules. The resultant microcapsules can be suspended in an aqueous solution to form stable oral doses of the drug.