Patents by Inventor Mimoun Ayoub

Mimoun Ayoub has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS OF TROFINETIDE
    Publication number: 20240109841
    Abstract: This disclosure describes compounds of Formula (I), stereoisomers, side compounds thereof, pharmaceutical compositions and methods of manufacturing such compounds, using silylation reagents and producing compositions and products made using such methods. More particularly, this disclosure describes manufacture of trofinetide and side products, compositions and products containing such compounds, for pharmaceutical uses to treat neurodegenerative or neurodevelopmental disorders.
    Type: Application
    Filed: November 21, 2023
    Publication date: April 4, 2024
    Inventors: Clive BLOWER, Matthew PETERSON, James Murray SHAW, James Anthony BONNAR, Etienne David Frank Philippe MONIOTTE, Martin Bernard Catherine BOUSMANNE, Cecilia BETTI, Karel Willy Luc DECROOS, Mimoun AYOUB
  • Compositions of trofinetide
    Patent number: 11866406
    Abstract: This disclosure describes compounds of Formula (I), stereoisomers, side compounds thereof, pharmaceutical compositions and methods of manufacturing such compounds, using silylation reagents and producing compositions and products made using such methods. More particularly, this disclosure describes manufacture of trofinetide and side products, compositions and products containing such compounds, for pharmaceutical uses to treat neurodegenerative or neurodevelopmental disorders.
    Type: Grant
    Filed: June 23, 2022
    Date of Patent: January 9, 2024
    Assignee: NEUREN PHARMACEUTICALS LIMITED
    Inventors: Clive Blower, Mathew Peterson, James Murray Shaw, James Anthony Bonnar, Etienne David Frank Philippe Moniotte, Martin Bernard Catherine Bousmanne, Cecilia Betti, Karel Willy Luc Decroos, Mimoun Ayoub
  • COMPOSITIONS OF TROFINETIDE
    Publication number: 20220324799
    Abstract: This disclosure describes compounds of Formula (I), stereoisomers, side compounds thereof, pharmaceutical compositions and methods of manufacturing such compounds, using silylation reagents and producing compositions and products made using such methods. More particularly, this disclosure describes manufacture of trofinetide and side products, compositions and products containing such compounds, for pharmaceutical uses to treat neurodegenerative or neurodevelopmental disorders.
    Type: Application
    Filed: June 23, 2022
    Publication date: October 13, 2022
    Inventors: CLIVE BLOWER, MATHEW PETERSON, JAMES MURRAY SHAW, JAMES ANTHONY BONNAR, ETIENNE DAVID FRANK PHILIPPE MONIOTTE, MARTIN BERNARD CATHERINE BOUSMANNE, CECILIA BETTI, KAREL WILLY LUC DECROOS, MIMOUN AYOUB
  • Compositions of trofinetide
    Patent number: 11370755
    Abstract: This disclosure describes compounds of Formula (I), stereoisomers, side compounds thereof, pharmaceutical compositions and methods of manufacturing such compounds, using silylation reagents and producing compositions and products made using such methods. More particularly, this disclosure describes manufacture of trofinetide and side products, compositions and products containing such compounds, for pharmaceutical uses to treat neurodegenerative or neurodevelopmental disorders.
    Type: Grant
    Filed: June 14, 2021
    Date of Patent: June 28, 2022
    Assignee: NEUREN PHARMACEUTICALS LIMITED
    Inventors: Clive Blower, Mathew Peterson, James Murray Shaw, James Anthony Bonnar, Etienne David Frank Philippe Moniotte, Martin Bernard Catherine Bousmanne, Cecilia Betti, Karel Willy Luc Decroos, Mimoun Ayoub
  • COMPOSITIONS OF TROFINETIDE
    Publication number: 20220055987
    Abstract: This disclosure describes compounds of Formula (I), stereoisomers, side compounds thereof, pharmaceutical compositions and methods of manufacturing such compounds, using silylation reagents and producing compositions and products made using such methods. More particularly, this disclosure describes manufacture of trofinetide and side products, compositions and products containing such compounds, for pharmaceutical uses to treat neurodegenerative or neurodevelopmental disorders.
    Type: Application
    Filed: June 14, 2021
    Publication date: February 24, 2022
    Inventors: CLIVE BLOWER, MATHEW PETERSON, JAMES MURRAY SHAW, JAMES ANTHONY BONNAR, ETIENNE DAVID FRANK PHILIPPE MONIOTTE, MARTIN BERNARD CATHERINE BOUSMANNE, CECILIA BETTI, KAREL WILLY LUC DECROOS, MIMOUN AYOUB
  • Controlled-Released Peptide Formulations
    Publication number: 20150148295
    Abstract: Described herein are methods and compositions for modulating the release and/or drug loading characteristics of encapsulated bioactive agents in polymer-based delivery systems via direct modification of the isoelectric point and/or net charge of the bioactive agent.
    Type: Application
    Filed: February 9, 2015
    Publication date: May 28, 2015
    Inventors: Kevin Burton, Torsten Woehr, Thomas R. Tice, Mimoun Ayoub
  • Controlled-released peptide formulations
    Patent number: 8951973
    Abstract: Described herein are methods and compositions for modulating the release and/or drug loading characteristics of encapsulated bioactive agents in polymer-based delivery systems via direct modification of the isoelectric point and/or net charge of the bioactive agent.
    Type: Grant
    Filed: August 28, 2009
    Date of Patent: February 10, 2015
    Inventors: Kevin Burton, Torsten Woehr, Thomas R. Tice, Mimoun Ayoub
  • Controlled-Released Peptide Formulations
    Publication number: 20120027805
    Abstract: Described herein are methods and compositions for modulating the release and/or drug loading characteristics of encapsulated bioactive agents in polymer-based delivery systems via direct modification of the isoelectric point and/or net charge of the bioactive agent.
    Type: Application
    Filed: August 28, 2009
    Publication date: February 2, 2012
    Applicant: Genzyme Corporation
    Inventors: Kevin Burton, Torsten Woehr, Thomas R. Tice, Mimoun Ayoub