Patents by Inventor Min Cong

Min Cong has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for Treating Metastasis with Cathepsin C Inhibitors
    Publication number: 20230321056
    Abstract: Provided herein are methods for treating metastasis of a cancer with a pharmaceutical composition comprising an effective amount of a cathepsin C (CTSC) inhibitor. The CTSC inhibitor, in some embodiments, is a compound of Formula (I), or a pharmaceutically acceptable salt thereof, for example, brensocatib. The treatment methods inhibit, slow, or reverse the progression of the metastasis. In some embodiments, the methods further comprise reducing neutrophil infiltration and/or formation of neutrophil extracellular traps (NETs).
    Type: Application
    Filed: September 10, 2021
    Publication date: October 12, 2023
    Inventors: Guohong HU, Yansen XIAO, Min CONG, Chenxi LIANG
  • Methods for detecting hepatic fibrosis and responsiveness to therapy
    Patent number: 11180810
    Abstract: This disclosure provides kits and methods for determining whether a subject is suffering from a liver disease, and/or whether the subject will be a responsive to a therapy for a liver disease. The disclosed methods comprise determining the miR profile of exosomes isolated from a body fluid of the subject.
    Type: Grant
    Filed: September 28, 2016
    Date of Patent: November 23, 2021
    Assignees: RESEARCH INSTITUTE AT NATIONWIDE CHILDREN'S HOSPITAL, BEIJING FRIENDSHIP HOSPITAL, CAPITAL MEDICAL UNIVERSITY
    Inventors: David Brigstock, Li Chen, Hong You, Min Cong
  • METHODS FOR DETECTING HEPATIC FIBROSIS AND RESPONSIVENESS TO THERAPY
    Publication number: 20180282810
    Abstract: This disclosure provides kits and methods for determining whether a subject is suffering from a liver disease, and/or whether the subject will be a responsive to a therapy for a liver disease. The disclosed methods comprise determining the miR profile of exosomes isolated from a body fluid of the subject.
    Type: Application
    Filed: September 28, 2016
    Publication date: October 4, 2018
    Applicants: RESEARCH INSTITUTE AT NATIONWIDE CHILDREN'S HOSPITAL, BEIJING FRIENDSHIP HOSPITAL, CAPITAL MEDICAL UNIVERSITY
    Inventors: David Brigstock, Li Chen, Hong You, Min Cong