Patents by Inventor Min J. Lee

Min J. Lee has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TRICYCLIC PROTEASOME ACTIVITY ENHANCING COMPOUNDS
    Publication number: 20180265519
    Abstract: Proteinopathies result from the proteasome not acting efficiently enough to eliminate harmful proteins and prevent the formation of the pathogenic aggregates. As described herein, inhibition of proteasome-associated deubiquitinase Usp14 results in increased proteasome efficiency. The present invention therefore provides novel compositions and methods for inhibition of Usp14, enhancement of proteasome activity and treatment of proteinopathies.
    Type: Application
    Filed: May 21, 2018
    Publication date: September 20, 2018
    Inventors: Daniel J. Finley, Randall W. King, Byung-Hoon Lee, Min J. Lee, Timothy C. Gahman
  • Tricyclic proteasome activity enhancing compounds
    Patent number: 9981981
    Abstract: Proteinopathies result from the proteasome not acting efficiently enough to eliminate harmful proteins and prevent the formation of the pathogenic aggregates. As described herein, inhibition of proteasome-associated deubiquitinase Usp14 results in increased proteasome efficiency. The present invention therefore provides novel compositions and methods for inhibition of Usp14, enhancement of proteasome activity and treatment of proteinopathies.
    Type: Grant
    Filed: December 17, 2014
    Date of Patent: May 29, 2018
    Assignee: President and Fellows of Harvard College
    Inventors: Daniel J. Finley, Randall W. King, Byung-Hoon Lee, Min J. Lee, Timothy C. Gahman
  • Tricyclic Proteasome Activity Enhancing Compounds
    Publication number: 20160039839
    Abstract: Proteinopathies result from the proteasome not acting efficiently enough to eliminate harmful proteins and prevent the formation of the pathogenic aggregates. As described herein, inhibition of proteasome-associated deubiquitinase Usp14 results in increased proteasome efficiency. The present invention therefore provides novel compositions and methods for inhibition of Usp14, enhancement of proteasome activity and treatment of proteinopathies.
    Type: Application
    Filed: December 17, 2014
    Publication date: February 11, 2016
    Inventors: Daniel J. Finley, Randall W. King, Byung-Hoon Lee, Min J. Lee, Timothy C. Gahman
  • Tricyclic proteasome activity enhancing compounds
    Patent number: 8933087
    Abstract: Proteinopathies result from the proteasome not acting efficiently enough to eliminate harmful proteins and prevent the formation of the pathogenic aggregates. As described herein, inhibition of proteasome-associated deubiquitinase Usp14 results in increased proteasome efficiency. The present invention therefore provides novel compositions and methods for inhibition of Usp14, enhancement of proteasome activity and treatment of proteinopathies.
    Type: Grant
    Filed: July 22, 2011
    Date of Patent: January 13, 2015
    Assignee: President and Fellows of Harvard College
    Inventors: Daniel J. Finley, Randall W. King, Byung-Hoon Lee, Min J. Lee, Timothy C. Gahman
  • Tricyclic Proteasome Activity Enhancing Compounds
    Publication number: 20130210845
    Abstract: Proteinopathies result from the proteasome not acting efficiently enough to eliminate harmful proteins and prevent the formation of the pathogenic aggregates. As described herein, inhibition of proteasome-associated deubiquitinase Usp14 results in increased proteasome efficiency. The present invention therefore provides novel compositions and methods for inhibition of Usp14, enhancement of proteasome activity and treatment of proteinopathies.
    Type: Application
    Filed: July 22, 2011
    Publication date: August 15, 2013
    Applicant: PRESIDENT AND FELLOWS OF HARVARD COLLEGE
    Inventors: Daniel J. Finley, Randall W. King, Byung-Hoon Lee, Min J. Lee, Timothy C. Gahman
  • Compositions and Methods for Enhancing Proteasome Activity
    Publication number: 20130045992
    Abstract: Proteinopathies result from the proteasome not acting efficiently enough to eliminate harmful proteins and prevent the formation of the pathogenic aggregates. As described herein, inhibition of proteasome-associated deubiquitinase Usp 14 results in increased proteasome efficiency. The present invention therefore provides novel compositions and methods for inhibition of Usp14, enhancement of proteasome activity and treatment of proteinopathies.
    Type: Application
    Filed: January 28, 2011
    Publication date: February 21, 2013
    Applicant: President and Fellows of Harvard College
    Inventors: Daniel J. Finley, Randall W. King, Byung-Hoon Lee, Min J. Lee, Timothy C. Gahman
  • Child calming toy with rythmic stimulation
    Patent number: 4718876
    Abstract: A child calming device comprising, in accordance with the preferred embodiment, a stuffed animal (10) having a pocket (88) within which is contained a heart beat simulating transducer (12) is disclosed. The transducer is actuated by application of pressure to an actuator (22) which is coupled to a switch (30) which drives an electronic circuit (40) contained within the housing (14) of the simulator (12). The power of the "simulated" heart beats may be regulated by adjustment of a potentiometer via a knurled knob (98).
    Type: Grant
    Filed: January 27, 1986
    Date of Patent: January 12, 1988
    Inventor: Min J. Lee