Patents by Inventor Min-Jeong Sohn

Min-Jeong Sohn has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • yapsin deficient mutant strain and process for the preparation of recombinant proteins using the same
    Patent number: 7262287
    Abstract: The present invention relates to a nucleic acid molecule comprising the HpYPS1 gene encoding H. polymorpha yapsin1, a polypeptide encoded by the nucleic acid molecule, a H. polymorpha mutant strain having reduced yapsin activity by mutation of the HpYPS gene encoding H. polymorpha yapsin1, a recombinant H. polymorpha strain expressing a foreign protein produced by introducing a gene encoding the foreign protein into the H. polymorpha mutant strain, and a process for preparing a foreign protein comprising culturing the recombinant H. polymorpha strain under conditions to express the foreign protein and isolating the foreign protein from the culture.
    Type: Grant
    Filed: June 28, 2003
    Date of Patent: August 28, 2007
    Assignees: Korea Research Institute of Bioscience and Biotechnology, Leadbio, Inc., Bioholdings Co., Ltd.
    Inventors: Hyun-Ah Kang, Sang-Ki Rhee, Min-Jeong Sohn, Jeong-Yoon Kim
  • Hansenula polymorpha yapsin deficient mutant strain and process for the preparation of recombinant proteins using the same
    Publication number: 20050239074
    Abstract: The present invention relates to a nucleic acid molecule comprising the HpYPS1 gene encoding H. polymorpha yapsin1, a polypeptide encoded by the nucleic acid molecule, a H. polymorpha mutant strain having reduced yapsin activity by mutation of the HpYPS gene encoding H. polymorpha yapsin1, a recombinant H. polymorpha strain expressing a foreign protein produced by introducing a gene encoding the foreign protein into the H. polymorpha mutant strain, and a process for preparing a foreign protein comprising culturing the recombinant H. polymorpha strain under conditions to express the foreign protein and isolating the foreign protein from the culture.
    Type: Application
    Filed: June 28, 2003
    Publication date: October 27, 2005
    Inventors: Hyun-Ah Kang, Sang-Ki Rhee, Min-Jeong Sohn, Jeong-Yoon Kim