Abstract: The present technology relates generally to compositions and methods of preventing or treating ischemic stroke. The present technology also relates to administering the anti-ASIC1a antibodies in effective amounts to treat a subject suffering from, or predisposed to, ischemic stroke.

Abstract: Provided are immunoglobulin-related compositions (e.g., antibodies or antigen binding fragments thereof) that specifically bind acid-sensing ion channel 1a (ASIC1a) protein and uses of the same. Also provided is a method of administering an effective amount of the anti-ASIC1a antibodies to treat a subject suffering from, or predisposed to, acidosis, or to treat a subject suffering from a disease caused by or related to altered ASIC1a activity and/or signaling, including ischemic stroke and related conditions.

Abstract: The present disclosure provides human antibodies and fragments thereof having binding specificity to the SARS-CoV-2 spike protein's receptor binding domain (RBD). The antibodies and fragments have strong affinity and potent neutralization ability against the SARS-CoV-2 virus and various mutant forms. Also provided are trimeric antibodies which have further enhanced neutralization capabilities. The antibodies and fragments thus may be used for preventing or treating SARS-CoV-2 viral infection or detecting the presence of the virus in a sample.

Abstract: A device for driving light-emitting diodes (LEDs) includes an address transceiver, a processor, and at least one power supply. The address transceiver stores a communication address and receives a Konnex (KNX) protocol signal carrying a driving address. The address transceiver generates a driving signal when the driving address corresponds to the communication address. The processor, electrically connected to the address transceiver, receives the driving signal and generates a power starting signal according to the driving signal. The power supply, electrically connected to the processor and at least one light-emitting diode (LED) module, receives the power starting signal and uses the power starting signal to drive the LED module.

Abstract: An electrical connector includes: an insulative housing having a tongue; an upper and lower rows of contacts secured to the insulative housing and exposed to two opposite faces of the tongue, the upper row of contacts including an upper ground contact and the lower row of contacts including a lower ground contact; and a metal plate disposed between the upper row of contacts and the lower row of contacts, wherein the metal plate has a pair of upper fingers contacting the upper ground contact and a pair of lower fingers contacting the lower ground contact.

Abstract: An electrical connector includes: an insulative housing having a tongue; an upper and lower rows of contacts secured to the insulative housing and exposed to two opposite faces of the tongue, the upper row of contacts including an upper ground contact and the lower row of contacts including a lower ground contact; and a metal plate disposed between the upper row of contacts and the lower row of contacts, wherein the metal plate has a pair of upper fingers contacting the upper ground contact and a pair of lower fingers contacting the lower ground contact.

Abstract: A method for making a terminal module includes providing a first terminal and a second terminal positioned in the first terminal, forming an insulator between the first terminal and the second terminal, and forming a latching flange on an outer surface of the first terminal. The latching flange forms at least one resisting surface.

Abstract: A method for making a terminal module includes providing a first terminal and a second terminal positioned in the first terminal, forming an insulator between the first terminal and the second terminal, and forming a latching flange on an outer surface of the first terminal. The latching flange forms at least one resisting surface.

Abstract: An exemplary cable connector includes a terminal module, a latching flange, and a housing. The terminal module includes a first terminal, a second terminal, and an insulator. The first terminal and the second terminal are insulated by the insulator. The latching flange is fixed on an outer surface of the terminal module. The housing is fixed on a periphery of the terminal module. The latching flange forms at least one resisting surface. An inner surface of the housing defines a latching groove corresponding to the latching flange. The latching groove forms at least one resisting surface corresponding to the at least one resisting surface of the latching flange. The latching flange is latched in the latching groove.

Abstract: An exemplary terminal module of a cable connector includes a first terminal, a second terminal positioned in the first terminal, an insulator positioned between the first terminal and the second terminal for insulating the first and second terminals from each other, and a latching flange disposed on an outer surface of the first terminal. The latching flange forms at least one resisting surface.

Abstract: An exemplary cable connector plug (20) includes a first contact (21). The first contact includes a contact portion (210) and an extension portion (211) extending from the contact portion along an axis of the cable connector plug. The extension portion includes a first columnar portion (2111), a neck portion (2112) and a second columnar portion (2113). The neck portion interconnects the first columnar portion and the second columnar portion. A periphery of a junction where the neck portion connects with the second columnar portion is curved from a point of the periphery distal from the second columnar portion to a point of the periphery distal from the neck portion. The cable connector plug has a relatively good mechanical strength and durability.

Abstract: An exemplary cable connector includes a housing, a terminal module including a first terminal and a second terminal, a printed circuit board fixed in the housing, and a cable including a first core and a second core. The terminal module is detachably assembled in a first end of the housing, and the first and second terminals are contacting the printed circuit board. The cable is fixed in a second end of the housing, and the first and the second cores of the cable are welded to the printed circuit board. The first and second terminals are electrically communicating with the first and second cores via the printed circuit board.

Abstract: An exemplary cable connector includes a housing, a terminal module including a first terminal and a second terminal, a printed circuit board fixed in the housing, and a cable including a first core and a second core. The terminal module is detachably assembled in a first end of the housing, and the first and second terminals are contacting the printed circuit board. The cable is fixed in a second end of the housing, and the first and the second cores of the cable are welded to the printed circuit board. The first and second terminals are electrically communicating with the first and second cores via the printed circuit board.

Abstract: An exemplary cable connector includes a terminal module, a latching flange, and a housing. The terminal module includes a first terminal, a second terminal, and an insulator. The first terminal and the second terminal are insulated by the insulator. The latching flange is fixed on an outer surface of the terminal module. The housing is fixed on a periphery of the terminal module. The latching flange forms at least one resisting surface. An inner surface of the housing defines a latching groove corresponding to the latching flange. The latching groove forms at least one resisting surface corresponding to the at least one resisting surface of the latching flange.

Abstract: An exemplary terminal module of a cable connector includes a first terminal, a second terminal positioned in the first terminal, an insulator positioned between the first terminal and the second terminal for insulating the first and second terminals from each other, and a latching flange disposed on an outer surface of the first terminal. The latching flange forms at least one resisting surface.

Abstract: An exemplary zoom lens system includes a negative first lens group and a positive second lens group. The first lens group includes a meniscus-shaped first lens with negative refracting power and a second lens with positive refracting power. The first lens has a concave surface facing an image side. The second lens group includes an aperture stop, a biconvex third lens with positive refracting power, and a meniscus-shaped fourth lens with negative refracting power. The fourth lens has a concave surface facing an object side. The first lens, the second lens, the aperture stop, the third lens and the fourth lens are aligned in that order from the object side to the image side.

Abstract: A Fourier transform lens system includes a first lens group having positive power, a second lens group having positive power, and a third lens group having negative power, all arranged on a common optical axis in that sequence. The first lens group includes a first positive meniscus lens, and a negative meniscus lens adjacent to the second lens group. The first positive meniscus lens has a concave lens surface facing toward a concave lens surface of the negative meniscus lens. The second lens group includes at least one bi-convex lens. The third lens group includes a second positive meniscus lens adjacent to the second lens group and a bi-concave lens. The second positive meniscus lens has a convex lens surface facing toward the second lens group. The Fourier transform lens system satisfies the following conditions: (1) 0.8<f2/f<1.4; (2) ?1.3<R12F/f<?0.7; (3) 0.35<R31F/f<0.75; and (4) 0.3<R32R/f<0.7.

Abstract: An exemplary cable connector plug (20) includes a contact (21) and an insulator (25). The first contact includes a contact portion (210) and an extension portion (211) extending from the contact portion along an axis of the cable connector plug. The first contact further includes a hooking portion (2115) provided at the extension portion. The insulator surrounds the hooking portion, and is lockingly engaged with the hooking portion such that when the extension portion is moved along an axis of the cable connector plug, the first insulator correspondingly moves in unison with the extension portion. The cable connector plug has good mechanical strength and stability.

Abstract: An exemplary cable connector plug (20) includes a contact (21) and an insulator (25). The first contact includes a contact portion (210) and an extension portion (211) extending from the contact portion along an axis of the cable connector plug. The first contact further includes a hooking portion (2115) provided at the extension portion. The insulator surrounds the hooking portion, and is lockingly engaged with the hooking portion such that when the extension portion is moved along an axis of the cable connector plug, the first insulator correspondingly moves in unison with the extension portion. The cable connector plug has good mechanical strength and stability.

Abstract: An exemplary cable connector plug (20) includes a first contact (21). The first contact includes a contact portion (210) and an extension portion (211) extending from the contact portion along an axis of the cable connector plug. The extension portion includes a first columnar portion (2111), a neck portion (2112) and a second columnar portion (2113). The neck portion interconnects the first columnar portion and the second columnar portion. A periphery of a junction where the neck portion connects with the second columnar portion is curved from a point of the periphery distal from the second columnar portion to a point of the periphery distal from the neck portion. The cable connector plug has a relatively good mechanical strength and durability.