Abstract: Provided are a gut bacterium strain and uses thereof, particularly, the gut bacterium strain with an accession number of GDMCC 62983 (Alistipes indistinctus Xia-1), and a method for the treatment and/or prevention of hyperuricemia using the gut bacterium strain of the present invention. The gut bacterium strain of the present invention has a therapeutic effect on lowering uric acid and a high safety, solving the technical problems of side effects caused by long-term intake of common drugs for hyperuricemia on the market, as well as the poor effect of controlling diet.

Abstract: The present invention provides the method and means for an efficient isolation of membrane-bound proteins from biological samples, e.g. in samples from raw or processed plant material, preferably defatted plant seed meal such as canola meal. The biological sample can be highly processed, e.g. by applying high temperature, pressure, or a chemical treatment and can be derived from seed matrices as well as other typical plant tissues for example seed, grain, leaf, root, or pollen. The invention comprises the provision of a novel extraction buffer (MEB) and its application in the method of the invention, wherein the buffer has a strong alkaline pH of 10 to 12.5 and comprises a soluble concentration of detergent at a level of 0.5% to 5%.

Abstract: Techniques include providing a mesh geometry for an image of an object to an application. In this way, an application that provides the image of the object can then overlay the mesh geometry onto the image. For example, when the object is a building, an image of a building is provided by a camera used by an application. The application can be configured to determine the three-dimensional location of the building based on the image provided by the camera. The application can be configured to determine a mesh geometry for the building based on the determined location. The application can be configured to obtain the mesh geometry and overlay the image of the building (virtual building) with the mesh geometry.

Abstract: A method including receiving a request for an anchor associated with a location, determining whether the location includes a structure, in response to determining the location includes a structure, retrieve data associated with the structure and determine if a quality associated with the data associated with the structure meets a criterion, and in response to determining the quality meets the criterion, return an anchor in response to the request.

Abstract: Methods are described herein for identifying and/or treating lymphoma patients that have one or more genomic mutations in a coding region of at least one BCL10 allele. Such patients can be resistant to commonly used cancer treatments and can benefit instead from treatment with at least one MALT1 inhibitor.

Abstract: A damping mechanism and a vehicle are provided. The damping mechanism includes: a spindle; an elastic cushion assembly used to couple the spindle and the vehicle body; a coupling arm having a first end used to be fixedly coupled to an axle of the wheel and a second end pivotally coupled to the spindle; and a locking assembly provided between the coupling arm and the spindle and used to switch the coupling arm and the spindle between at least two locking states and a unlocking state. In the unlocking state, the coupling arm is rotatable, and in the locking states, the coupling arm is locked; in each of the locking states, the coupling arm is in different locking positions relative to the spindle; and when the coupling arm is in different locking positions, the coupling arm is at different angles to a horizontal plane.

Abstract: A processing method of NPR steel rebar coil is disclosed. The NPR steel rebar is cold processed and has a diameter of less than 14 mm, and has a yield strength of 800˜950 MPa, a tensile strength of 900˜1100 MPa, and a elongation of not less than 20%. The processing method comprises: an I-shaped placing step L20, an uncoiling step L30, a flattening step L40, a pointing step L50, a butt welding step L60, a hydraulic head-pushing step L70, a cold drawn smoothing step L80, a grit blasting step L90, an in-situ inline annealing step L10, an air-cooled tempering step L11, a coiling step L12, a placing step L13, a flattening step L14, a cold drawn spiral ribbing step L15, a straightening step L16, and a coiling step L17. The method can achieve full intelligence, meet the processing requirements and the automatic intelligent production requirements of NPR steel rebar coil.

Abstract: A processing method of NPR steel rebar rod is disclosed. The NPR steel rebar is cold processed and has a yield strength of 800˜950 MPa, a tensile strength of 900˜1100 MPa, and a percentage elongation at maximum force of not less than 10˜40%. The processing method comprises the following steps: a I-shaped placing step L20, an uncoiling step L30, a flattening step L40, a butt welding step L50, a sandblasting step L60, a straightening step L70, a pointing step L80, a hydraulic head-pushing step L90, a cold drawn spiral ribbing step L10, a straight forward continuous wire drawing and traction step L11, a pre-straightening step L12, a fine straightening step L13, and a cutting-off step L14. The processing method can meet the automatic intelligent production requirements of NPR steel rebar, cold rolled spiral NPR steel rebar, and pre-stressed NPR steel rebar.

Abstract: A processing method of NPR steel rebar coil is disclosed. The NPR steel rebar is cold processed and has a diameter of less than 14 mm, and has a yield strength of 800˜950 MPa, a tensile strength of 900˜1100 MPa, and a elongation of not less than 20%. The processing method comprises: a I-shaped placing step L20, an uncoiling step L30, a flattening step L40, a pointing step L50, a butt welding step L60, a hydraulic head-pushing step L70, a cold drawn smoothing step L80, a grit blasting step L90, an in-situ inline annealing step L10, an air-cooled tempering step L11, a coiling step L12, a placing step L13, a flattening step L14, a cold drawn spiral ribbing step L15, a straightening step L16, and a coiling step L17. The method can achieve full intelligence, meet the processing requirements and the automatic intelligent production requirements of NPR steel rebar coil.

Abstract: An NPR non-magnetic steel material for rock bolt and a production method thereof are disclosed. The NPR non-magnetic steel material for rock bolt has a composition, in weight percent, consisting of: C: 0.4-0.7%, MN: 15-20%, Cr: 1-18%, Si: 0.3-3%, Ca: 0.05-0.15%, Cu: ?0.03%, Ni: ?0.02%, S: ?0.001%, P: ?0.001%, and the rest being Fe and unavoidable impurity elements. The NPR non-magnetic steel material for rock bolt and the production method thereof effectively solve the problems of steel materials for rock bolt in the prior art such as strong magnetism, low tensile strength and low effective elongation. The NPR non-magnetic steel material for rock bolt has a fully-austenitized structure and is non-magnetic, its yield strength is adjustable in the range of 600-1000 MPa, and its elongation is adjustable in the range of 20-60%.

Abstract: An NPR steel material for rock bolt and a production method thereof are disclosed. The NPR steel material for rock bolt has a composition, in weight percent, consisting of: C: 0.4-0.7%, Mn: 15-20%, Si: ?0.1%, Cu: ?0.03%, Cr: ?0.01%, Ni: ?0.02%, S: ?0.001%, P: ?0.001%, and the rest being Fe and unavoidable impurity elements. The NPR steel material for rock bolt and the production method thereof effectively solve the problem that rock bolts in the prior art have low tensile strength and low effective elongation. The NPR steel material for rock bolt has a yield strength adjustable in the range of 500-1100 MPa, and an elongation adjustable in the range of 10-80%.

Abstract: A processing method of NPR steel rebar rod is disclosed. The NPR steel rebar is cold processed and has a yield strength of 800˜950 MPa, a tensile strength of 900˜1100 MPa, and a percentage elongation at maximum force of not less than 10˜40%. The processing method comprises the following steps: a I-shaped placing step L20, an uncoiling step L30, a flattening step L40, a butt welding step L50, a sandblasting step L60, a straightening step L70, a pointing step L80, a hydraulic head-pushing step L90, a cold drawn spiral ribbing step L10, a straight forward continuous wire drawing and traction step L11, a pre-straightening step L12, a fine straightening step L13, and a cutting-off step L14. The processing method can meet the automatic intelligent production requirements of NPR steel rebar, cold rolled spiral NPR steel rebar, and pre-stressed NPR steel rebar.

Abstract: A damping mechanism and a vehicle are provided. The damping mechanism includes: a spindle; an elastic cushion assembly used to couple the spindle and the vehicle body; a coupling arm having a first end used to be fixedly coupled to an axle of the wheel and a second end pivotally coupled to the spindle; and a locking assembly provided between the coupling arm and the spindle and used to switch the coupling arm and the spindle between at least two locking states and a unlocking state. In the unlocking state, the coupling arm is rotatable, and in the locking states, the coupling arm is locked; in each of the locking states, the coupling arm is in different locking positions relative to the spindle; and when the coupling arm is in different locking positions, the coupling arm is at different angles to a horizontal plane.

Abstract: An NPR rock bolt according to the present disclosure comprises a bolt body (1), a tray (2) and a lock (3). The bolt body (1) is an NPR spiral steel bar, an outer surface of the NPR spiral steel bar is provided with a number of convex spiral ribs, and the spiral ribs have a spiral structure. The tray (2) and the lock (3) are directly sleeved on a tail of the NPR spiral steel bar. The NPR bolt according to the present disclosure can effectively solve the problem in the prior art that conventional rock bolts have a low elongation and cannot meet the requirement of large deformation of the surrounding rock.

Abstract: The present disclosure is directed to compositions and methods for treating presbyopia. The compositions can include a cholinesterase inhibitor, such as neostigmine, echothiophate, diisopropyl fluorophosphates, or physostigmine, and/or a mitoic agent. The compositions can act alone or synergistically, for example, to improve the accommodative and focusing ability of the eye while minimizing the side effects from each compound.

Abstract: An NPR non-magnetic steel material for rock bolt and a production method thereof are disclosed. The NPR non-magnetic steel material for rock bolt has a composition, in weight percent, consisting of: C: 0.4-0.7%, Mn: 15-20%, Cr: 1-18%, Si: 0.3-3%, Ca: 0.05-0.15%, Cu: ?0.03%, Ni: ?0.02%, S: ?0.001%, P: ?0.001%, and the rest being Fe and unavoidable impurity elements. The NPR non-magnetic steel material for rock bolt and the production method thereof effectively solve the problems of steel materials for rock bolt in the prior art such as strong magnetism, low tensile strength and low effective elongation. The NPR non-magnetic steel material for rock bolt has a fully-austenitized structure and is non-magnetic, its yield strength is adjustable in the range of 600-1000 MPa, and its elongation is adjustable in the range of 20-60%.

Abstract: An NPR steel material for rock bolt and a production method thereof are disclosed. The NPR steel material for rock bolt has a composition, in weight percent, consisting of: C: 0.4-0.7%, Mn: 15-20%, Si: ?0.1%, Cu: ?0.03%, Cr: ?0.01%, Ni: ?0.02%, S: ?0.001%, P: ?0.001%, and the rest being Fe and unavoidable impurity elements. The NPR steel material for rock bolt and the production method thereof effectively solve the problem that rock bolts in the prior art have low tensile strength and low effective elongation. The NPR steel material for rock bolt has a yield strength adjustable in the range of 500-1100 MPa, and an elongation adjustable in the range of 10-80%.

Abstract: The present invention provides the method and means for an efficient isolation of membrane-bound proteins from biological samples, e.g. in samples from raw or processed plant material, preferably defatted plant seed meal such as canola meal. The biological sample can be highly processed, e.g. by applying high temperature, pressure, or a chemical treatment and can be derived from seed matrices as well as other typical plant tissues for example seed, grain, leaf, root, or pollen. The invention comprises the provision of a novel extraction buffer (MEB) and its application in the method of the invention, wherein the buffer has a strong alkaline pH of 10 to 12.5 and comprises a soluble concentration of detergent at a level of 0.5% to 5%.

Abstract: This invention relates to a detection system for measuring a fluorescent signal in a fluorescent assay. The system comprises a probe having a small sensing surface bound with a fluorescent label, and a light source and a detector both mounted at the proximal side of the sensing surface of the substrate. The invention also relates to a method for detecting an analyte in a liquid sample using a probe tip having a small surface area (?5 mm) and a high molecular weight polymer (?1 MD) having multiple binding molecules and multiple fluorescent labels. The binding reaction is accelerated by flowing the reaction solutions laterally and moving the probe tip up and down in the reaction vessels. The invention furthers relates to a fluorescent labeling composition comprising a cross-linked FICOLL® molecule having a plurality of binding molecules and a plurality of fluorescent labels.