Patents by Inventor Min Xie

Min Xie has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20170219478
    Abstract: A method and apparatus for identifying one or more target constituents (e.g., white blood cells) within a biological sample is provided. The method includes the steps of: a) adding at least one colorant to the sample; b) disposing the sample into a chamber defined by at least one transparent panel; c) creating at least one image of the sample quiescently residing within the chamber; d) identifying target constituents within the sample image; e) quantitatively analyzing at least some of the identified target constituents within the image relative to one or more predetermined quantitatively determinable features; and f) identifying at least one type of target constituent within the identified target constituents using the quantitatively determinable features.
    Type: Application
    Filed: April 14, 2017
    Publication date: August 3, 2017
    Inventors: David Herzog, Zhizhou Wang, Stephen C. Wardlaw, Min Xie
  • Publication number: 20170115271
    Abstract: A method for analyzing a biologic fluid sample includes the steps of: a) providing a spatially mapped chamber; b) providing a predetermined repeatable non-uniform spatial distribution of one or more constituents within the sample, which distribution indicates the presence or absence of a statistically significant number of constituents within the sample in each chamber sub-region; c) selecting one or more image techniques for each sub-region based on the presence or absence of the statistically significant number of one or more constituents in that sub-region as indicated by the distribution; d) creating image data representative of the biologic fluid sample in each sub-region, using the one or more image techniques selected for that sub-region; and e) analyzing the sample.
    Type: Application
    Filed: January 4, 2017
    Publication date: April 27, 2017
    Inventors: Min Xie, Stephen C. Wardlaw
  • Patent number: 9576180
    Abstract: A method for analyzing a biologic fluid sample includes the steps of: a) providing a spatially mapped chamber; b) providing a predetermined repeatable non-uniform spatial distribution of one or more constituents within the sample, which distribution indicates the presence or absence of a statistically significant number of constituents within the sample in each chamber sub-region; c) selecting one or more image techniques for each sub-region based on the presence or absence of the statistically significant number of one or more constituents in that sub-region as indicated by the distribution; d) creating image data representative of the biologic fluid sample in each sub-region, using the one or more image techniques selected for that sub-region; and e) analyzing the sample.
    Type: Grant
    Filed: December 6, 2013
    Date of Patent: February 21, 2017
    Assignee: Abbott Point of Care, Inc.
    Inventors: Min Xie, Stephen C. Wardlaw
  • Publication number: 20170044107
    Abstract: The present disclosure provides compounds, pharmaceutical compositions and related methods for the treatment of cancer, e.g., castration-resistant prostate cancer (CRPC). Specifically, the present disclosure provides a series of 8-hydroxyquinoline derivatives which show cytotoxic effects on androgen-independent prostate cancer cells.
    Type: Application
    Filed: April 21, 2015
    Publication date: February 16, 2017
    Inventors: Min Xie, Sheng Ding
  • Publication number: 20170009036
    Abstract: A structured porous metamaterial includes a three-dimensional matrix of at least one repeating base unit. The matrix is formed from an array of at least eight base units, each base unit including a platonic solid including at least one shaped void, wherein each base unit has void geometry tailored to provide a porosity of between 0.3 and 0.97, and to provide the metamaterial with a response that includes a Poisson's ratio of 0 to ?0.5 when under tension and compression, or negative linear compression (NLC), negative area compression (NAC), zero linear compression (ZLC), or zero area compression (ZAC) behaviour when under pressure.
    Type: Application
    Filed: January 20, 2015
    Publication date: January 12, 2017
    Inventors: Yi Min Xie, Jianhu Shen, Shiwei Zhou, Xiaodong Huang
  • Publication number: 20170011253
    Abstract: A method and apparatus for identifying platelets within a whole blood sample. The method includes the steps of: a) adding at least one colorant to the whole blood sample, which colorant is operable to tag platelets; b) disposing the blood sample into a chamber defined by at least one transparent panel; c) imaging at least a portion of the sample quiescently residing within the chamber to create one or more images; and d) identifying one or more platelets within the sample using an analyzer adapted to identify the platelets based on quantitatively determinable features within the image using a analyzer, which quantitatively determinable features include intensity differences.
    Type: Application
    Filed: September 20, 2016
    Publication date: January 12, 2017
    Inventors: Changhua Yu, Min Xie, Yiming Wu
  • Publication number: 20160330636
    Abstract: Provided are a method and apparatus for implementing self recovery of a base station device, which relate to the technical field of communications. The method includes that: it is monitored, in real time, whether a base station device generates a fault or performance index event; when it is monitored that the base station device generates the fault or performance index event, a self-recovery alarm configuration file is searched according to the monitored fault or performance index event; corresponding self-recovery execution information is acquired according to the found self-recovery alarm configuration file; and self-recovery is implemented according to the self-recovery execution information. By means of automatic self-recovery on an alarm based on a found pre-provided self-recovery rule, the technical solution can reduce the complexity of manually handling a fault, and reduces the dependence of fault handling on a professional engineer.
    Type: Application
    Filed: June 18, 2014
    Publication date: November 10, 2016
    Inventor: Min XIE
  • Patent number: 9483686
    Abstract: A method and apparatus for identifying platelets within a whole blood sample. The method includes the steps of: a) adding at least one colorant to the whole blood sample, which colorant is operable to tag platelets; b) disposing the blood sample into a chamber defined by at least one transparent panel; c) imaging at least a portion of the sample quiescently residing within the chamber to create one or more images; and d) identifying one or more platelets within the sample using an analyzer adapted to identify the platelets based on quantitatively determinable features within the image using a analyzer, which quantitatively determinable features include intensity differences.
    Type: Grant
    Filed: June 3, 2015
    Date of Patent: November 1, 2016
    Assignee: Abbott Point of Care, Inc.
    Inventors: Changhua Yu, Min Xie, Yiming Wu
  • Publication number: 20150317506
    Abstract: A method for analyzing a biologic fluid sample includes the steps of: a) providing a spatially mapped chamber; b) providing a predetermined repeatable non-uniform spatial distribution of one or more constituents within the sample, which distribution indicates the presence or absence of a statistically significant number of constituents within the sample in each chamber sub-region; c) selecting one or more image techniques for each sub-region based on the presence or absence of the statistically significant number of one or more constituents in that sub-region as indicated by the distribution; d) creating image data representative of the biologic fluid sample in each sub-region, using the one or more image techniques selected for that sub-region; and e) analyzing the sample.
    Type: Application
    Filed: December 6, 2013
    Publication date: November 5, 2015
    Inventors: Min XIE, Stephen C. WARDLAW
  • Patent number: 9149416
    Abstract: The present invention provides an insecticidal emulsion cleansing system comprising a clear oil-in-water (o/w) emulsion wherein the oil phase contains an ionic surfactant and an insecticide suspended together as nanometer sized particles in the water phase; and wherein the water phase contains an oppositely charged polymer. The insecticide is preferably a pyrethroid such as a natural pyrethrin or a synthetic pyrethroid. Suitable pyrethroids include pyrethroid esters and pyrethroid ethers.
    Type: Grant
    Filed: August 21, 2009
    Date of Patent: October 6, 2015
    Assignee: WELLMARK INTERNATIONAL
    Inventors: Min Xie, Robin Rudolph, Stephanie Ponder
  • Publication number: 20150269413
    Abstract: A method and apparatus for identifying platelets within a whole blood sample. The method includes the steps of: a) adding at least one colorant to the whole blood sample, which colorant is operable to tag platelets; b) disposing the blood sample into a chamber defined by at least one transparent panel; c) imaging at least a portion of the sample quiescently residing within the chamber to create one or more images; and d) identifying one or more platelets within the sample using an analyzer adapted to identify the platelets based on quantitatively determinable features within the image using a analyzer, which quantitatively determinable features include intensity differences.
    Type: Application
    Filed: June 3, 2015
    Publication date: September 24, 2015
    Inventors: Changhua Yu, Min Xie, Yiming Wu
  • Patent number: 9082166
    Abstract: A method and apparatus for identifying platelets within a whole blood sample. The method includes the steps of: a) adding at least one colorant to the whole blood sample, which colorant is operable to tag platelets; b) disposing the blood sample into a chamber defined by at least one transparent panel; c) imaging at least a portion of the sample quiescently residing within the chamber to create one or more images; and d) identifying one or more platelets within the sample using an analyzer adapted to identify the platelets based on quantitatively determinable features within the image using a analyzer, which quantitatively determinable features include intensity differences.
    Type: Grant
    Filed: December 28, 2012
    Date of Patent: July 14, 2015
    Assignee: Abbott Point of Care, Inc.
    Inventors: Changhua Yu, Min Xie, Yiming Wu
  • Patent number: 9064301
    Abstract: A method and apparatus for analyzing white blood cells (WBCs) within a whole blood sample quiescently residing within a chamber is provided. The chamber is defined by at least one transparent panel, and the whole blood sample includes at least one colorant operable to differentially identify at least one WBC type from another WBC type within the sample. The method includes the steps of: a) creating at least one image of the sample quiescently residing within the chamber; b) identifying portions of the sample image, with each portion representing a single WBC; c) compressing the sample image portions using a first compression algorithm; and d) one of compressing a remainder of the sample image not included in the portions using a second compression algorithm, or discarding the remainder.
    Type: Grant
    Filed: April 14, 2011
    Date of Patent: June 23, 2015
    Assignee: Abbott Point of Care, Inc.
    Inventors: Min Xie, Zhizhou Wang
  • Patent number: 8837803
    Abstract: A method and apparatus for determining a cell volume of a red blood cell is provided. The method includes the steps of: a) depositing a sample into an analysis chamber, the chamber defined by an first panel interior surface, a second panel interior surface, and a known or determinable height, which height is such that at least one red blood cell subject to a sphering agent assumes a partially compressed spherical shape in contact with the interior surfaces; b) imaging the at least one partially compressed spherical red blood cell contacting the interior surfaces, and producing image signals; c) determining a radius of the partially compressed spherical red blood cell from the image signals; and d) determining a volume of the imaged red blood cell using the determined radius.
    Type: Grant
    Filed: December 30, 2010
    Date of Patent: September 16, 2014
    Assignee: Abbott Point of Care, Inc.
    Inventors: Zhizhou Wang, Min Xie, Anil Patil, Chong Chen, Shaohong Wang, Cord Mueller
  • Patent number: 8819898
    Abstract: A handle structure contains a body, a housing, a cover, a controlling member, and a resilient element. The body includes an outer surface and an inner surface, the outer face has a non-grip face and a flat rim, and the inner surface has a connecting column. The housing is hollow and includes a front fringe, a rear fringe, and a L-shaped recess. The cover is fixed on a rear side of the housing and used to fix a handle structure on a plate. The controlling member is fitted into the housing and includes a front end and a rear end. The front end connects with the connecting column via the front fringe. The controlling member also includes a raised portion fixed in the L-shaped recess. The resilient element located between the controlling member and the cover. Hence, the controlling member is pushed by the resilient element to move toward the body.
    Type: Grant
    Filed: May 17, 2013
    Date of Patent: September 2, 2014
    Inventor: Jian-Min Xie
  • Patent number: 8786694
    Abstract: A method and apparatus for imaging a biologic fluid sample quiescently residing within a chamber is provided. The method includes the steps of: a) positioning the chamber at a Z-axis position relative to an objective lens having a lens axis, wherein the Z-axis is parallel to the lens axis; b) moving one or both of the chamber and the objective lens relative to one another at a velocity along the Z-axis; and c) creating one or more images of the biologic fluid sample as one or both of the chamber and the objective lens are moving at a velocity relative to one another within a focus search range along the Z-axis.
    Type: Grant
    Filed: December 30, 2010
    Date of Patent: July 22, 2014
    Assignee: Abbott Point of Care, Inc.
    Inventors: Min Xie, Yang Zhang
  • Publication number: 20140082888
    Abstract: A handle structure contains a body, a housing, a cover, a controlling member, and a resilient element. The body includes an outer surface and an inner surface, the outer face has a non-grip face and a flat rim, the inner surface has a connecting column. The housing is hollow and including a front fringe, a rear fringe, and a L-shaped recess. The cover is fixed on a rear side of the housing and used to fix a handle structure on a plate. The controlling member is fitted into the housing and includes a front end and a rear end, the front end connects with the connecting column via the front fringe. The controlling member also includes a raised portion fixed in the L-shaped recess. The resilient element located between the controlling member and the cover, hence the controlling member is pushed by the resilient element to move toward the body.
    Type: Application
    Filed: May 17, 2013
    Publication date: March 27, 2014
    Inventor: Jian-Min Xie
  • Publication number: 20120263369
    Abstract: A method and apparatus for analyzing white blood cells (WBCs) within a whole blood sample quiescently residing within a chamber is provided. The chamber is defined by at least one transparent panel, and the whole blood sample includes at least one colorant operable to differentially identify at least one WBC type from another WBC type within the sample. The method includes the steps of: a) creating at least one image of the sample quiescently residing within the chamber; b) identifying portions of the sample image, with each portion representing a single WBC; c) compressing the sample image portions using a first compression algorithm; and d) one of compressing a remainder of the sample image not included in the portions using a second compression algorithm, or discarding the remainder.
    Type: Application
    Filed: April 14, 2011
    Publication date: October 18, 2012
    Applicant: ABBOTT POINT OF CARE, INC.
    Inventors: Min Xie, Zhizhou Wang
  • Patent number: 8170354
    Abstract: A system and method for rendering images, and performing operations such as windowing and leveling, when the parameters of a client appliance are known and rendering images when the parameters of a client appliance are unknown. The invention also considers the rendering from the client appliance perspective and the server appliance perspective.
    Type: Grant
    Filed: April 18, 2011
    Date of Patent: May 1, 2012
    Assignees: Siemens Medical Solutions USA, Inc., Siemens Aktiengesellschaft
    Inventors: Qiang Cheng, Michael Pisot, Min Xie
  • Patent number: 8121419
    Abstract: A system and method for rendering images, and performing operations such as windowing and leveling, when the parameters of a client appliance are known and rendering images when the parameters of a client appliance are unknown. The invention also considers the rendering from the client appliance perspective and the server appliance perspective.
    Type: Grant
    Filed: April 18, 2011
    Date of Patent: February 21, 2012
    Assignees: Siemens Medical Solutions USA, Inc., Siemens Aktiengesellschaft
    Inventors: Qiang Cheng, Michael Pisot, Min Xie