Abstract: A sample introduction device for mass spectrometry includes a sample plate. The sample plate includes a carriage and at least one nozzle. The nozzle is made of a conductive material. The nozzle is mounted on the carriage. The nozzle includes a sample-receiving chamber, a spout, and a gas passage. The spout communicates with the sample-receiving chamber. The gas passage extends between opposite sides of the nozzle. In use, a sample is loaded into the sample-receiving chamber. An ion source creates a high voltage difference between the nozzle and an analyzer inlet such that the sample in the sample-receiving chamber is ionized to produce ions when leaving the nozzle. Meanwhile, a gas supply device supplies gas to the gas passage to create a negative pressure at the spout such that the exiting gas accelerates the ions away from the nozzle.

Abstract: A multiple solid phase microextraction (m-SPME) thermal desorption ionization device which desorbs an analyte and moves it into an entry of a mass spectrometer for mass spectrometry analysis is provided. The device has a charge producing unit, a heating unit and a sampling unit. The sampling unit provides a plurality of probes. The analyte is attached to the probes, and then the probes are inserted through a passage of the heating unit to instantly vaporize the analyte for ionization and analysis in conjunction with the charge producing unit and the mass spectrometer. Thus, the time needed for analyte analysis is shortened. A mass spectrometer system having the thermal desorption ionization device and an analytical method for mass spectrometry are also provided.

Abstract: An electrospray-assisted laser desorption ionization device includes: an electrospray unit including a nozzle; a voltage supplying member disposed to establish between the nozzle and a receiving unit a potential difference such that liquid drops of the electrospray medium formed at the nozzle are laden with charges, and such that the liquid drops are forced to leave the nozzle toward the receiving unit along a traveling path; a laser desorption unit adapted to irradiate a sample such that, upon irradiation, analytes contained in the sample are desorbed to fly along a flying path which intersects the traveling path so as to enable the analytes to be occluded in the liquid drops, and such that as a result of dwindling in size of the liquid drops when moving along the traveling path, charges of the liquid drops will pass on to the analytes occluded therein to form ionized analytes.

Abstract: An electrospray-assisted laser desorption ionization device includes: an electrospray unit including a nozzle; a voltage supplying member disposed to establish between the nozzle and a receiving unit a potential difference such that liquid drops of the electrospray medium formed at the nozzle are laden with charges, and such that the liquid drops are forced to leave the nozzle toward the receiving unit along a traveling path; a laser desorption unit adapted to irradiate a sample such that, upon irradiation, analytes contained in the sample are desorbed to fly along a flying path which intersects the traveling path so as to enable the analytes to be occluded in the liquid drops, and such that as a result of dwindling in size of the liquid drops when moving along the traveling path, charges of the liquid drops will pass on to the analytes occluded therein to form ionized analytes.