Patents by Inventor Minako KANDA

Minako KANDA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ß2GPI GENE EXPRESSION-SUPPRESSING NUCLEIC ACID CONJUGATE
    Publication number: 20180193471
    Abstract: The present invention provides a nucleic acid conjugate comprising: a double-stranded nucleic acid consisting of a sense strand and an antisense strand and comprising a duplex region of at least 11 base pairs; and a ligand part, wherein an oligonucleotide with a strand length of 17 to 30 nucleotides in the antisense strand is complementary to a target ?2GPI mRNA sequence, and the 3? end or 5? end of the sense strand has a ligand part represented by following formula (I), formula (II), formula (III), formula (IV) or formula (V).
    Type: Application
    Filed: July 15, 2016
    Publication date: July 12, 2018
    Applicant: Kyowa Hakko Kirin Co., Ltd.
    Inventors: Kazutaka NAGATOMO, Kazuhiro MASUDA, Minako KANDA, Yoji YAMADA, Hiroto IWAI, Asana MAKINO, Shintaro HOSOE, Takeshi KUBOYAMA, Keiji UEHARA, Yasuhiro SUZUKI
  • NUCLEIC ACID CAPABLE OF INHIBITING EXPRESSION OF BETA-2GPI
    Publication number: 20170247700
    Abstract: The present invention provides a nucleic acid having activity to suppress expression of ?2GPI, a pharmaceutical composition comprising the nucleic acid, and a prophylactic or therapeutic drug containing the nucleic acid for autoimmune diseases such as APS, SLE and the like and thrombosis in hemodialysis.
    Type: Application
    Filed: May 13, 2017
    Publication date: August 31, 2017
    Applicant: KYOWA HAKKO KIRIN CO., LTD.
    Inventors: Yoji YAMADA, Hiroto IWAI, Kazuhiro MASUDA, Minako KANDA
  • NUCLEIC ACID CAPABLE OF INHIBITING EXPRESSION OF BETA-2GPI
    Publication number: 20170247701
    Abstract: The present invention provides a nucleic acid having activity to suppress expression of ?2GPI, a pharmaceutical composition comprising the nucleic acid, and a prophylactic or therapeutic drug containing the nucleic acid for autoimmune diseases such as APS, SLE and the like and thrombosis in hemodialysis.
    Type: Application
    Filed: May 13, 2017
    Publication date: August 31, 2017
    Applicant: KYOWA HAKKO KIRIN CO., LTD.
    Inventors: Yoji YAMADA, Hiroto IWAI, Kazuhiro MASUDA, Minako KANDA
  • NUCLEIC ACID CAPABLE OF INHIBITING EXPRESSION OF BETA-2GPI
    Publication number: 20160333346
    Abstract: The present invention provides a nucleic acid having activity to suppress expression of ?2GPI, a pharmaceutical composition comprising the nucleic acid, and a prophylactic or therapeutic drug containing the nucleic acid for autoimmune diseases such as APS, SLE and the like and thrombosis in hemodialysis.
    Type: Application
    Filed: January 16, 2015
    Publication date: November 17, 2016
    Applicant: KYOWA HAKKO KIRIN CO., LTD.
    Inventors: Yoji YAMADA, Hiroto IWAI, Kazuhiro MASUDA, Minako KANDA