Patents by Inventor Minako Sakakibara

Minako Sakakibara has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5817467
    Abstract: The object of the invention is to provide a reagent for quantitatively determining creatine kinase with improved storability in liquid form as well as a method for quantitatively determining creatine kinase with stable measurements. Disclosed are a method for quantitatively determining creatine kinase, which comprises activating creatine kinase in a sample in an aqueous medium in coexistence with a trivalent phosphorus compound and a sulfhydryl-containing compound and then determining creatine kinase activity; a method for stabilizing a sulfhydryl-containing compound, which comprises allowing a trivalent phosphorus compound to coexist with a sulfhydryl-containing compound; and a reagent for quantitatively determining creatine kinase, which comprises a trivalent phosphorus compound, a sulfhydryl-containing compound, and a reaction substrate for creatine kinase.
    Type: Grant
    Filed: November 14, 1996
    Date of Patent: October 6, 1998
    Assignee: Kyowa Medex Co., Ltd.
    Inventors: Norihito Aoyama, Minako Sakakibara
  • Patent number: 5783382
    Abstract: Disclosed is a method for stably storing a liquid diagnostic reagent, comprising air-hermetically keeping the liquid diagnostic reagent in a closed container in the presence of a disoxidant therein. Preferably, at least one of the liquid diagnostic reagent and the disoxidant is covered with a separating container made of a material pervious to oxygen but not to solutions. The liquid diagnostic reagent may comprise an enzyme or an indicator.
    Type: Grant
    Filed: January 24, 1997
    Date of Patent: July 21, 1998
    Assignee: Kyowa Medex Co., Ltd.
    Inventors: Norihito Aoyama, Minako Sakakibara, Akira Miike
  • Patent number: 5424204
    Abstract: Glucose 6-phosphate dehydrogenase is stabilized in a clinical assay reagent with at least one stabilizer selected from among hydroxylamines, aldehyde scavengers dimethylthiocarbamoyl chloride, 2-(2-aminoethylamine) ethanol, and their salts. The reagent may be in liquid or lyophilized form.
    Type: Grant
    Filed: August 23, 1994
    Date of Patent: June 13, 1995
    Assignee: Kyowa Medex Co., Ltd.
    Inventors: Norihito Aoyama, Minako Sakakibara