Patents by Inventor Mine YURTSEVER

Mine YURTSEVER has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • DRG-MDM2-4 for use as a novel mouse double minute 2 (MDM2) inhibitor
    Patent number: 12661354
    Abstract: The invention relates to compounds according to formula (I) and pharmaceutically acceptable derivatives thereof for use as novel inhibitors of Mouse Double Minute 2 (MDM2) activity by inhibiting interactions between MDM2 and its natural negative regulator, p53. Pharmaceutical compositions containing a compound of Formula (I), or a derivative thereof, including compositions that also contain one or more additional antiproliferative agents, can be used in methods of treating proliferative diseases, including various cancers.
    Type: Grant
    Filed: February 17, 2021
    Date of Patent: June 23, 2026
    Assignees: BAHCESEHIR UNIVERSITESI, ISTANBUL TEKNIK UNIVERSITESI
    Inventors: Serdar Durdagi, Timucin Avsar, Muge Didem Orhan, Maide Nur Paksoy, Gulsah Aydin, Mine Yurtsever
  • DRG-MDM2-1 for use as a novel Mouse Double Minute 2 (MDM2) inhibitor
    Patent number: 12595232
    Abstract: The invention relates to compound shown with formula (I) or a pharmaceutically acceptable derivative thereof for use as a novel inhibitor of MDM2 activity.
    Type: Grant
    Filed: February 16, 2021
    Date of Patent: April 7, 2026
    Assignees: BAHCESEHIR UNIVERSITESI, ISTANBUL TEKNIK UNIVERSITESI
    Inventors: Timucin Avsar, Serdar Durdagi, Muge Didem Orhan, Maide Nur Paksoy, Gulsah Aydin, Mine Yurtsever
  • MAO-B inhibitor DRG-MAOB-1 for use in treatment of neurodegenerative diseases
    Patent number: 12528794
    Abstract: The invention relates to compound shown with formula (I) or a pharmaceutically acceptable derivative thereof for use as a novel inhibitor of MAO-B.
    Type: Grant
    Filed: February 25, 2021
    Date of Patent: January 20, 2026
    Assignees: BAHCESEHIR UNIVERSITESI, ISTANBUL TEKNIK UNIVERSITESI, AGRI IBRAHIM CECEN UNIVERSITESI STRATEJI DAIRE BASK., ISTANBUL GEDIK UNIVERSITESI
    Inventors: Serdar Durdagi, Mine Yurtsever, Busecan Aksoydan, Yusuf Serhat Is, Murat Senturk
  • DRG-MDM2-6 for use as a novel mouse double minute 2 (MDM2) inhibitor
    Patent number: 12502392
    Abstract: The invention relates to compound shown with formula (I) or a pharmaceutically acceptable derivative thereof for use as a novel inhibitor of MDM2 activity.
    Type: Grant
    Filed: February 17, 2021
    Date of Patent: December 23, 2025
    Assignees: BAHCESEHIR UNIVERSITESI, ISTANBUL TEKNIK UNIVERSITESI
    Inventors: Mine Yurtsever, Muge Didem Orhan, Maide Nur Paksoy, Gulsah Aydin, Timucin Avsar, Serdar Durdagi
  • Selective MAO-B inhibitor DRG-MAOB-2 for use in treatment of neurodegenerative diseases
    Patent number: 12478613
    Abstract: The invention relates to compound shown with formula (I) or a pharmaceutically acceptable derivative thereof for use as a novel inhibitor of MAO-B.
    Type: Grant
    Filed: February 25, 2021
    Date of Patent: November 25, 2025
    Assignees: BAHCESEHIR UNIVERSITESI, AGRI IBRAHIM CECEN UNIVERSITESI STRATEJI DAIRE BASK., ISTANBUL GEDIK UNIVERSITESI, ISTANBUL TEKNIK UNIVERSITESI REKTORLUGU
    Inventors: Serdar Durdagi, Mine Yurtsever, Yusuf Serhat Is, Busecan Aksoydan, Murat Senturk
  • DRG-MDM2-2 FOR USE AS A NOVEL MOUSE DOUBLE MINUTE 2 (MDM2) INHIBITOR
    Publication number: 20240270730
    Abstract: The invention relates to compound shown with formula I or a pharmaceutically acceptable derivative thereof for use as a novel inhibitor of MDM2 activity.
    Type: Application
    Filed: February 17, 2021
    Publication date: August 15, 2024
    Inventors: Serdar DURDAGI, Muge Didem ORHAN, Timucin AVSAR, Mine YURTSEVER, Maide Nur PAKSOY, Gulsah AYDIN
  • DRG-MDM2-6 FOR USE AS A NOVEL MOUSE DOUBLE MINUTE 2 (MDM2) INHIBITOR
    Publication number: 20230098888
    Abstract: The invention relates to compound shown with formula (I) or a pharmaceutically acceptable derivative thereof for use as a novel inhibitor of MDM2 activity.
    Type: Application
    Filed: February 17, 2021
    Publication date: March 30, 2023
    Inventors: Mine YURTSEVER, Muge Didem ORHAN, Maide Nur PAKSOY, Gulsah AYDIN, Timucin AVSAR, Serdar DURDAGI
  • DRG-MDM2-1 FOR USE AS A NOVEL MOUSE DOUBLE MINUTE 2 (MDM2) INHIBITOR
    Publication number: 20230073261
    Abstract: The invention relates to compound shown with formula (I) or a pharmaceutically acceptable derivative thereof for use as a novel inhibitor of MDM2 activity.
    Type: Application
    Filed: February 16, 2021
    Publication date: March 9, 2023
    Inventors: Timucin AVSAR, Serdar DURDAGI, Muge Didem ORHAN, Maide Nur PAKSOY, Gulsah AYDIN, Mine YURTSEVER
  • DRG-MDM2-4 FOR USE AS A NOVEL MOUSE DOUBLE MINUTE 2 (MDM2) INHIBITOR
    Publication number: 20230071340
    Abstract: The invention relates to compound shown with formula (I) or a pharmaceutically acceptable derivative thereof for use as a novel inhibitor of MDM2 activity.
    Type: Application
    Filed: February 17, 2021
    Publication date: March 9, 2023
    Inventors: Serdar DURDAGI, Timucin AVSAR, Muge Didem ORHAN, Maide Nur PAKSOY, Gulsah AYDIN, Mine YURTSEVER
  • DRG-MDM2-3 FOR USE AS A NOVEL MOUSE DOUBLE MINUTE 2 (MDM2) INHIBITOR
    Publication number: 20230067644
    Abstract: The invention relates to compound shown with formula (I) or a pharmaceutically acceptable derivative thereof for use as a novel inhibitor of MDM2 activity.
    Type: Application
    Filed: February 17, 2021
    Publication date: March 2, 2023
    Inventors: Serdar DURDAGI, Muge ORHAN, Timucin AVSAR, Maide PAKSOY, Gulsah AYDIN, Mine YURTSEVER
  • DRG-MDM2-5 FOR USE AS A NOVEL MOUSE DOUBLE MINUTE 2 (MDM2) INHIBITOR
    Publication number: 20230063449
    Abstract: The invention relates to compound shown with formula (I) or a pharmaceutically acceptable derivative thereof for use as a novel inhibitor of MDM2 activity.
    Type: Application
    Filed: February 17, 2021
    Publication date: March 2, 2023
    Inventors: Serdar DURDAGI, Timucin AVSAR, Mine YURTSEVER, Gulsah AYDIN, Maide Nur PAKSOY, Muge Didem ORHAN