Abstract: The present disclosure provides a method for preparing mesenchymal stem cell-derived extracellular vesicle, the mesenchymal stem cell-derived extracellular vesicle prepared by the method, and use of the mesenchymal stem cell-derived extracellular vesicle for reducing adipogenesis and treating osteoarthritis. The mesenchymal stem cell-derived extracellular vesicle of the present disclosure achieves the effect of reducing adipogenesis and treating osteoarthritis through various efficacy experiments.

Abstract: The present invention relates to a method for preparing a modified stem cell, including the following steps: a cell culture step: culturing stem cells in a first culture medium of a culture dish at a predetermined cell density, and removing the first culture medium after a first culture time to obtain a first cell intermediate; an activity stimulation step: preserving the first cell intermediate in a freezing container having a cell cryopreservation solution, and performing a constant temperature stimulation treatment or a variable temperature stimulation treatment for at least more than 1 day; and a product collection step: after completing the activity stimulation step, placing the freezing container in an environment at a thawing temperature for thawing, and then removing the cell cryopreservation solution to obtain the modified stem cell. The modified stem cell can release at least one or more of IL-4, IL-5, IL-13, G-CSF, Fractalkine, and EGF.

Abstract: A metal adhesion layer may be formed on a bottom and a sidewall of a trench prior to formation of a metal plug in the trench. A plasma may be used to modify the phase composition of the metal adhesion layer to increase adhesion between the metal adhesion layer and the metal plug. In particular, the plasma may cause a shift or transformation of the phase composition of the metal adhesion layer to cause the metal adhesion layer to be composed of a (111) dominant phase. The (111) dominant phase of the metal adhesion layer increases adhesion between the metal adhesion layer.

Abstract: A variable aperture module includes a blade assembly, a positioning element, a driving part and pressing structures. The blade assembly includes movable blades disposed around an optical axis to form a light passable hole with an adjustable size. Each movable blade has a positioning hole and a movement hole adjacent thereto. The positioning element includes positioning structures disposed respectively corresponding to the positioning holes. The driving part includes a rotation element disposed corresponding to the movement holes and is rotatable with respect to the positioning element. The pressing structures are disposed respectively corresponding to the movable blades. Each pressing structure is at least disposed into at least one of the positioning hole and the movement hole of the corresponding movable blade. Each pressing structure at least presses against at least one of the corresponding one positioning structure and the rotation element.

Abstract: A forming method of a processing curve in a stamping process is provided. The method includes the following steps. A plurality of processing curves are established, and an optimization target is set for the processing curves according to material characteristics of a workpiece, process requirements and a finished product CAD file. At least two of the processing curves are selected and superimposed to form a basic forming curve, wherein each subsection of the basic forming curve corresponds to a selected processing curve. Whether the selected processing curve in each subsection of the basic forming curve matches the optimization target is determined.

Abstract: The present disclosure relates to an integrated chip. The integrated chip includes an image sensing element disposed within a substrate. A gate structure is disposed along a front-side of the substrate. A back-side of the substrate includes one or more first angled surfaces defining a central diffuser disposed over the image sensing element. The back-side of the substrate further includes second angled surfaces defining a plurality of peripheral diffusers laterally surrounding the central diffuser. The plurality of peripheral diffusers are a smaller size than the central diffuser.

Abstract: A display device includes a display panel. The display panel has a functional display area. The functional display area includes a plurality of display pixels and a plurality of light transmitting regions. The plurality of display pixels are around by the plurality of the light transmitting regions. A boundary between one of the plurality of display pixels and one of the plurality of light transmitting regions comprises an arc segment.

Abstract: A part processing planning method includes the following steps. Firstly, a specific tolerance of a nominal size of a part is obtained. Then, a predetermined tolerance of each of processes is obtained. Then, using a process dimension chain establishing technique, at least one predetermined tolerance associated with the specification tolerance from the predetermined tolerances is obtained. Then, at least one predetermined tolerance associated with the specification tolerance is accumulated to obtain a size cumulative tolerance. Then, whether the size cumulative tolerance meets the specification tolerance is determined. Then, at least one predetermined tolerance associated with the specification tolerance is re-allocated when the cumulative tolerance does not meet the specification tolerance, such that the size cumulative tolerance is within the specification tolerance.

Abstract: A vision inspection and correction method, which uses an image adjustment software/device to separate the eyes of the inspected person on an independent display screen, and the visual mark seen by the same vision is designed to be misaligned; through the guidance and interaction of the inspector and the inspected person, the inspector can adjust the image operation to zoom in or out, shift, focus, diverge, and rotate, etc., so that the inspected person's binocular images can be clearly distinguished and adjusted. Then, the binocular images are aligned, and the inspector will implant the correction parameters during the image adjustment process into 3D projectors, VR (virtual reality), AR (augmented reality device), MR hybrid reality device and other equipment to adjust the binocular digital image parameters, so users have, or can provide to a lens maker, personalized adjustment for comfortable images of both eyes.

Abstract: A vision inspection and correction method, which mainly uses an image adjustment software/device to separate the eyes of the inspected person on an independent display screen, and the visual mark seen by the same vision is designed to be misaligned; through the guidance and interaction of the inspector and the inspected person, the inspector can adjust the image operation to zoom in/out/shift/focus/diverge/rotate, etc., so that the inspected person's binocular images can be clearly distinguished and adjusted.

Abstract: A part processing planning method includes the following steps. Firstly, a specific tolerance of a nominal size of a part is obtained. Then, a predetermined tolerance of each of processes is obtained. Then, using a process dimension chain establishing technique, at least one predetermined tolerance associated with the specification tolerance from the predetermined tolerances is obtained. Then, at least one predetermined tolerance associated with the specification tolerance is accumulated to obtain a size cumulative tolerance. Then, whether the size cumulative tolerance meets the specification tolerance is determined. Then, at least one predetermined tolerance associated with the specification tolerance is re-allocated when the cumulative tolerance does not meet the specification tolerance, such that the size cumulative tolerance is within the specification tolerance.

Abstract: A carrier includes at least one sucking member, a pressure-differentiating device, an optical unit and an image-capturing unit. The at least one sucking member, made of a flexible transparent material, has a plurality of micro holes extending in a first direction by penetrating through two opposing surfaces of the at least one sucking member. The pressure-differentiating device, connected with the at least one sucking member, is to have the at least one sucking member to perform a pressure-differentiated suction upon a workpiece. The optical unit is to capture an image of the workpiece through the at least one sucking member and to refract/reflect the image by an image-forming angle. The image-capturing unit is to capture and further output the image refracted/reflected by the optical unit in a real-time manner.

Abstract: An on-line measuring system, a datum calibrating method, a deviation measuring method and a computer-readable medium are provided. The datum calibrating method includes following steps. A work piece is scanned by a scanning unit to obtain a global point cloud data. A local CAD data of the work piece is obtained according to a predetermined range. A local CAD geometric feature of the local CAD data is obtained. A local point cloud data of the global point cloud data is obtained according to a local range corresponding to the predetermined range. A local scanning geometric feature of the local point cloud data is obtained. The local scanning geometric feature and the local CAD geometric feature are compared to obtain at least one spatial freedom limit. A system basis is obtained according to six spatial freedom limits, if the number of the at least one spatial freedom limit reaches six.

Abstract: An on-line measuring system, a datum calibrating method, a deviation measuring method and a computer-readable medium are provided. The datum calibrating method includes following steps. A work piece is scanned by a scanning unit to obtain a global point cloud data. A local CAD data of the work piece is obtained according to a predetermined range. A local CAD geometric feature of the local CAD data is obtained. A local point cloud data of the global point cloud data is obtained according to a local range corresponding to the predetermined range. A local scanning geometric feature of the local point cloud data is obtained. The local scanning geometric feature and the local CAD geometric feature are compared to obtain at least one spatial freedom limit. A system basis is obtained according to six spatial freedom limits, if the number of the at least one spatial freedom limit reaches six.

Abstract: A surface measuring device includes a rotary platform, a shifting lever, a measuring module, and a control module. The rotary platform carries an object under test and rotates the object under test at a rotating speed. The shifting lever is above the rotary platform. The measuring module disposed on the shifting lever moves to measurement positions on the shifting lever and performs a surface height measurement at a sampling frequency to sampling points on a surface of the object under test when located at one measurement position. The control module selectively adjusts the rotational speed for the rotary platform or the sampling frequency for the measuring module according to the measurement position of the measuring module on the shifting lever in order to fit a distance between the sampling points on at least one part of the surface of the object under test to a sampling rule.

Abstract: A surface measuring device includes a rotary platform, a shifting lever, a measuring module, and a control module. The rotary platform carries an object under test and rotates the object under test at a rotating speed. The shifting lever is above the rotary platform. The measuring module disposed on the shifting lever moves to measurement positions on the shifting lever and performs a surface height measurement at a sampling frequency to sampling points on a surface of the object under test when located at one measurement position. The control module selectively adjusts the rotational speed for the rotary platform or the sampling frequency for the measuring module according to the measurement position of the measuring module on the shifting lever in order to fit a distance between the sampling points on at least one part of the surface of the object under test to a sampling rule.

Abstract: A panel including a substrate, a plurality of wirings and a protection stacked layer is provided. The substrate has a device area, a bonding area and a wiring area connected between the device area and the bonding area. The wirings extend from the device area to the bonding area through the wiring area. The protection stacked layer extends from a side of the wiring area adjacent to the device area towards a side of the bonding area and is located on the wirings.

Abstract: A panel including a substrate, a plurality of wirings and a protection stacked layer is provided. The substrate has a device area, a bonding area and a wiring area connected between the device area and the bonding area. The wirings extend from the device area to the bonding area through the wiring area. The protection stacked layer extends from a side of the wiring area adjacent to the device area towards a side of the bonding area and is located on the wirings.

Abstract: The instant disclosure relates to a manufacturing method of a porous composite film. The manufacturing method includes processing a first porous film and a second porous film and includes the following steps: providing a pressing unit, a film-shaping unit, and a cooling unit; intersecting the first and second porous films at an angle; stacking the first and second porous films in forming a half-finished porous composite film; pressing the half-finished porous composite film by the pressing unit at a temperature T1 and under a tension S1; relieving the pressing force against the half-finished porous composite film thermally by the film-shaping unit at a temperature T2; and maintaining the half-finished porous composite film at a pre-determined tension by the cooling unit at a temperature T3.

Abstract: The instant disclosure relates to a manufacturing method of a porous composite film. The manufacturing method includes processing a first porous film and a second porous film and includes the following steps: providing a pressing unit, a film-shaping unit, and a cooling unit; intersecting the first and second porous films at an angle; stacking the first and second porous films in forming a half-finished porous composite film; pressing the half-finished porous composite film by the pressing unit at a temperature T1 and under a tension S1; relieving the pressing force against the half-finished porous composite film thermally by the film-shaping unit at a temperature T2; and maintaining the half-finished porous composite film at a pre-determined tension by the cooling unit at a temperature T3.